SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d7e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUH_A_CAMA422_0 (CAMPHOR 5-MONOOXYGENASE)	1d7e	PHOTOACTIVE YELLOW PROTEIN (Halorhodospira halophila)	4 / 6	PHE A 92 THR A 70 VAL A 120 VAL A 105	None HC4 A 126 ( 4.6A) None None	1.09A	2zuhA-1d7eA: undetectable	2zuhA-1d7eA: 15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IQQ_A_D16A402_1 (THYMIDYLATE SYNTHASE)	1d7e	PHOTOACTIVE YELLOW PROTEIN (Halorhodospira halophila)	5 / 7	TYR A 42 ILE A 31 ASP A 34 GLY A 37 PHE A 62	HC4 A 126 (-4.2A) None None None HC4 A 126 (-4.7A)	1.47A	4iqqA-1d7eA: undetectable	4iqqA-1d7eA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IQQ_D_D16D402_1 (THYMIDYLATE SYNTHASE)	1d7e	PHOTOACTIVE YELLOW PROTEIN (Halorhodospira halophila)	5 / 8	TYR A 42 ILE A 31 ASP A 34 GLY A 37 PHE A 62	HC4 A 126 (-4.2A) None None None HC4 A 126 (-4.7A)	1.46A	4iqqD-1d7eA: 0.5	4iqqD-1d7eA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_B_SASB804_2 (SEPIAPTERIN REDUCTASE)	1d7e	PHOTOACTIVE YELLOW PROTEIN (Halorhodospira halophila)	3 / 3	LEU A 23 MET A 18 ASP A 34	None	0.78A	4j7xB-1d7eA: undetectable	4j7xB-1d7eA: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X66_A_MTXA402_1 (THYMIDYLATE SYNTHASE)	1d7e	PHOTOACTIVE YELLOW PROTEIN (Halorhodospira halophila)	5 / 12	ILE A 31 ASP A 34 GLY A 37 PHE A 62 ASP A 53	None None None HC4 A 126 (-4.7A) None	1.11A	5x66A-1d7eA: undetectable 5x66B-1d7eA: 0.0	5x66A-1d7eA: 20.45 5x66B-1d7eA: 20.45

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZUH_A_CAMA422_0","CAMPHOR 5-MONOOXYGENASE","1d7e","PHOTOACTIVE YELLOW PROTEIN","Halorhodospira halophila",4,"PHE A  92;THR A  70;VAL A 120;VAL A 105","None;HC4 A 126 ( 4.6A);None;None","1.09A","2zuhA-1d7eA:undetectable","2zuhA-1d7eA:15.11"],["4IQQ_A_D16A402_1","THYMIDYLATE SYNTHASE","1d7e","PHOTOACTIVE YELLOW PROTEIN","Halorhodospira halophila",5,"TYR A  42;ILE A  31;ASP A  34;GLY A  37;PHE A  62","HC4 A 126 (-4.2A);None;None;None;HC4 A 126 (-4.7A)","1.47A","4iqqA-1d7eA:undetectable","4iqqA-1d7eA:18.21"],["4IQQ_D_D16D402_1","THYMIDYLATE SYNTHASE","1d7e","PHOTOACTIVE YELLOW PROTEIN","Halorhodospira halophila",5,"TYR A  42;ILE A  31;ASP A  34;GLY A  37;PHE A  62","HC4 A 126 (-4.2A);None;None;None;HC4 A 126 (-4.7A)","1.46A","4iqqD-1d7eA:0.5","4iqqD-1d7eA:18.21"],["4J7X_B_SASB804_2","SEPIAPTERIN REDUCTASE","1d7e","PHOTOACTIVE YELLOW PROTEIN","Halorhodospira halophila",3,"LEU A  23;MET A  18;ASP A  34","None","0.78A","4j7xB-1d7eA:undetectable","4j7xB-1d7eA:19.10"],["5X66_A_MTXA402_1","THYMIDYLATE SYNTHASE;THYMIDYLATE SYNTHASE","1d7e","PHOTOACTIVE YELLOW PROTEIN","Halorhodospira halophila",5,"ILE A  31;ASP A  34;GLY A  37;PHE A  62;ASP A  53","None;None;None;HC4 A 126 (-4.7A);None","1.11A","5x66A-1d7eA:undetectable;5x66B-1d7eA:0.0","5x66A-1d7eA:20.45;5x66B-1d7eA:20.45"]]