SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d9s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MNE_A_DEXA784_1 (GLUCOCORTICOID RECEPTOR)	1d9s	CYCLIN-DEPENDENT KINASE 4 INHIBITOR B (Mus musculus)	5 / 12	MET A 48 GLY A 17 GLN A 18 LEU A 57 THR A 87	None	1.32A	3mneA-1d9sA: undetectable	3mneA-1d9sA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WSJ_A_MK1A201_1 (PROTEASE)	1d9s	CYCLIN-DEPENDENT KINASE 4 INHIBITOR B (Mus musculus)	5 / 9	LEU A 85 ALA A 79 ASP A 78 LEU A 111 ILE A 120	None	1.29A	3wsjA-1d9sA: undetectable	3wsjA-1d9sA: 26.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AX8_A_SAMA1474_1 (WBDD)	1d9s	CYCLIN-DEPENDENT KINASE 4 INHIBITOR B (Mus musculus)	4 / 6	ARG A 23 ASP A 86 GLU A 82 LEU A 56	None	1.24A	4ax8A-1d9sA: 0.0	4ax8A-1d9sA: 15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_A_SAMA401_1 (METHYLTRANSFERASE NSUN4)	1d9s	CYCLIN-DEPENDENT KINASE 4 INHIBITOR B (Mus musculus)	3 / 3	ASP A 78 ARG A 81 ASP A 68	None	0.75A	4fp9A-1d9sA: undetectable	4fp9A-1d9sA: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_C_SAMC401_1 (METHYLTRANSFERASE NSUN4)	1d9s	CYCLIN-DEPENDENT KINASE 4 INHIBITOR B (Mus musculus)	3 / 3	ASP A 78 ARG A 81 ASP A 68	None	0.75A	4fp9C-1d9sA: undetectable	4fp9C-1d9sA: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_F_SAMF401_1 (METHYLTRANSFERASE NSUN4)	1d9s	CYCLIN-DEPENDENT KINASE 4 INHIBITOR B (Mus musculus)	3 / 3	ASP A 78 ARG A 81 ASP A 68	None	0.75A	4fp9F-1d9sA: undetectable	4fp9F-1d9sA: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E4D_B_BEZB202_0 (HYDROXYNITRILE LYASE)	1d9s	CYCLIN-DEPENDENT KINASE 4 INHIBITOR B (Mus musculus)	4 / 7	VAL A 90 THR A 87 LEU A 59 MET A 46	None	0.95A	5e4dA-1d9sA: undetectable 5e4dB-1d9sA: undetectable	5e4dA-1d9sA: 17.92 5e4dB-1d9sA: 17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NJ9_K_SAMK500_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	1d9s	CYCLIN-DEPENDENT KINASE 4 INHIBITOR B (Mus musculus)	3 / 3	THR A 12 GLU A 63 ASN A 36	None	0.87A	6nj9K-1d9sA: undetectable	6nj9K-1d9sA: 17.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3MNE_A_DEXA784_1","GLUCOCORTICOID RECEPTOR","1d9s","CYCLIN-DEPENDENT KINASE 4 INHIBITOR B","Mus musculus",5,"MET A  48;GLY A  17;GLN A  18;LEU A  57;THR A  87","None","1.32A","3mneA-1d9sA:undetectable","3mneA-1d9sA:20.23"],["3WSJ_A_MK1A201_1","PROTEASE","1d9s","CYCLIN-DEPENDENT KINASE 4 INHIBITOR B","Mus musculus",5,"LEU A  85;ALA A  79;ASP A  78;LEU A 111;ILE A 120","None","1.29A","3wsjA-1d9sA:undetectable","3wsjA-1d9sA:26.76"],["4AX8_A_SAMA1474_1","WBDD","1d9s","CYCLIN-DEPENDENT KINASE 4 INHIBITOR B","Mus musculus",4,"ARG A  23;ASP A  86;GLU A  82;LEU A  56","None","1.24A","4ax8A-1d9sA:0.0","4ax8A-1d9sA:15.32"],["4FP9_A_SAMA401_1","METHYLTRANSFERASE NSUN4","1d9s","CYCLIN-DEPENDENT KINASE 4 INHIBITOR B","Mus musculus",3,"ASP A  78;ARG A  81;ASP A  68","None","0.75A","4fp9A-1d9sA:undetectable","4fp9A-1d9sA:17.43"],["4FP9_C_SAMC401_1","METHYLTRANSFERASE NSUN4","1d9s","CYCLIN-DEPENDENT KINASE 4 INHIBITOR B","Mus musculus",3,"ASP A  78;ARG A  81;ASP A  68","None","0.75A","4fp9C-1d9sA:undetectable","4fp9C-1d9sA:17.43"],["4FP9_F_SAMF401_1","METHYLTRANSFERASE NSUN4","1d9s","CYCLIN-DEPENDENT KINASE 4 INHIBITOR B","Mus musculus",3,"ASP A  78;ARG A  81;ASP A  68","None","0.75A","4fp9F-1d9sA:undetectable","4fp9F-1d9sA:17.43"],["5E4D_B_BEZB202_0","HYDROXYNITRILE LYASE","1d9s","CYCLIN-DEPENDENT KINASE 4 INHIBITOR B","Mus musculus",4,"VAL A  90;THR A  87;LEU A  59;MET A  46","None","0.95A","5e4dA-1d9sA:undetectable;5e4dB-1d9sA:undetectable","5e4dA-1d9sA:17.92;5e4dB-1d9sA:17.92"],["6NJ9_K_SAMK500_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","1d9s","CYCLIN-DEPENDENT KINASE 4 INHIBITOR B","Mus musculus",3,"THR A  12;GLU A  63;ASN A  36","None","0.87A","6nj9K-1d9sA:undetectable","6nj9K-1d9sA:17.03"]]