SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d9z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 6 THR A  48
GLY A  39
THR A  43
ILE A 411
 None
 0.82A 1gtnD-1d9zA:
undetectable
1gtnE-1d9zA:
0.0		 1gtnD-1d9zA:
7.86
1gtnE-1d9zA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 8 VAL A  56
VAL A 337
TYR A 391
LEU A 334
 None
 0.91A 1igxA-1d9zA:
undetectable		 1igxA-1d9zA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		3 / 3 ARG A 489
ARG A 484
ARG A 593
 None
 0.99A 1l7fA-1d9zA:
undetectable		 1l7fA-1d9zA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		3 / 3 ARG A 489
ARG A 484
ARG A 593
 None
 0.98A 1l7hA-1d9zA:
0.0		 1l7hA-1d9zA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 12 GLY A  44
GLY A  42
ILE A 411
LEU A 401
THR A  36
 ATP  A 700 (-3.0A)
ATP  A 700 (-3.4A)
None
None
None
 1.07A 1p91B-1d9zA:
2.3		 1p91B-1d9zA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 8 GLY A  39
THR A  43
ILE A 411
THR A  48
 None
 0.80A 1utdB-1d9zA:
0.0
1utdC-1d9zA:
0.0		 1utdB-1d9zA:
7.86
1utdC-1d9zA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 8 GLY A  39
THR A  43
ILE A 411
THR A  48
 None
 0.81A 1utdF-1d9zA:
0.0
1utdG-1d9zA:
0.0		 1utdF-1d9zA:
7.86
1utdG-1d9zA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 8 GLY A  39
THR A  43
ILE A 411
THR A  48
 None
 0.81A 1utdJ-1d9zA:
0.0
1utdK-1d9zA:
0.0		 1utdJ-1d9zA:
7.86
1utdK-1d9zA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 5 PRO A 376
GLY A 353
ASN A 352
GLY A 349
 None
 1.04A 1zlqA-1d9zA:
0.0		 1zlqA-1d9zA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 5 ASP A 207
GLY A 217
ALA A 242
ILE A 243
 None
 0.90A 2aofA-1d9zA:
undetectable		 2aofA-1d9zA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 5 ASP A 207
GLY A 217
ALA A 242
ILE A 243
 None
 0.81A 2aohB-1d9zA:
0.0		 2aohB-1d9zA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 5 SER A 141
VAL A  90
VAL A 142
SER A  91
 None
 1.32A 2j9cA-1d9zA:
0.0
2j9cB-1d9zA:
0.0
2j9cC-1d9zA:
0.0		 2j9cA-1d9zA:
10.96
2j9cB-1d9zA:
10.96
2j9cC-1d9zA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		3 / 3 LYS A 225
ARG A 162
VAL A 241
 None
 0.90A 2r2vC-1d9zA:
0.0
2r2vD-1d9zA:
0.0		 2r2vC-1d9zA:
4.52
2r2vD-1d9zA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 12 LEU A  24
LEU A  38
GLY A  39
ARG A 569
THR A  48
 None
 1.32A 2yhdA-1d9zA:
undetectable		 2yhdA-1d9zA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 8 GLY A 416
ILE A 538
VAL A 514
THR A  41
 None
None
None
ATP  A 700 (-3.5A)
 0.89A 2yoeB-1d9zA:
3.0
2yoeC-1d9zA:
3.1		 2yoeB-1d9zA:
19.64
2yoeC-1d9zA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 12 PHE A  81
LEU A   7
ALA A  54
VAL A  62
THR A  60
 None
 1.03A 3cwkA-1d9zA:
0.0		 3cwkA-1d9zA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 9 GLY A  27
VAL A  32
ILE A 390
VAL A  52
VAL A  56
 None
 1.46A 3fhjD-1d9zA:
undetectable		 3fhjD-1d9zA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 9 GLY A  27
VAL A  32
ILE A 390
VAL A  52
VAL A  56
 None
 1.46A 3fhjF-1d9zA:
undetectable		 3fhjF-1d9zA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 9 GLY A  27
VAL A  32
ILE A 390
VAL A  52
VAL A  56
 None
 1.46A 3fi0D-1d9zA:
undetectable		 3fi0D-1d9zA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 9 GLY A  27
VAL A  32
ILE A 390
VAL A  52
VAL A  56
 None
 1.45A 3fi0H-1d9zA:
undetectable		 3fi0H-1d9zA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 8 GLY A  27
VAL A  32
ILE A 390
VAL A  52
VAL A  56
 None
 1.44A 3fi0I-1d9zA:
undetectable		 3fi0I-1d9zA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 9 GLY A  27
VAL A  32
ILE A 390
VAL A  52
VAL A  56
 None
 1.46A 3fi0K-1d9zA:
undetectable		 3fi0K-1d9zA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 9 GLY A  27
VAL A  32
ILE A 390
VAL A  52
VAL A  56
 None
 1.47A 3fi0R-1d9zA:
undetectable		 3fi0R-1d9zA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 4 ARG A 492
ASP A 419
GLY A 416
THR A 587
 None
 1.46A 3k4vB-1d9zA:
0.0		 3k4vB-1d9zA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 5 GLY A   3
ASP A 135
ARG A 134
GLN A  55
 None
 1.35A 3qx3A-1d9zA:
2.1		 3qx3A-1d9zA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 5 GLY A   3
ASP A 135
ARG A 134
GLN A  55
 None
 1.32A 3qx3B-1d9zA:
2.6		 3qx3B-1d9zA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 5 LEU A 148
GLY A 147
PHE A 249
ARG A 123
 None
 1.02A 3smtA-1d9zA:
0.0		 3smtA-1d9zA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		3 / 3 ASP A 460
LEU A 475
VAL A 498
 None
 0.67A 4jecB-1d9zA:
undetectable		 4jecB-1d9zA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 12 PHE A 379
ASN A 387
LEU A  61
VAL A 337
ILE A  63
 None
 1.25A 4k39A-1d9zA:
undetectable		 4k39A-1d9zA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		3 / 3 HIS A  34
VAL A  52
LEU A  28
 None
 0.72A 4m2vA-1d9zA:
0.0		 4m2vA-1d9zA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 5 GLY A 217
GLU A 239
HIS A 240
ASP A 228
 None
 1.18A 5c0oH-1d9zA:
4.7		 5c0oH-1d9zA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 7 VAL A  52
LEU A 334
VAL A  62
THR A  60
 None
 1.00A 5e4dA-1d9zA:
0.0
5e4dB-1d9zA:
0.0		 5e4dA-1d9zA:
14.81
5e4dB-1d9zA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 6 HIS A 248
GLU A 208
ALA A 129
TYR A  88
 None
 0.96A 5igiA-1d9zA:
undetectable		 5igiA-1d9zA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		5 / 9 ALA A  54
VAL A  56
LEU A  28
ILE A 390
ILE A 336
 None
 1.00A 5nunA-1d9zA:
0.0		 5nunA-1d9zA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 6 LEU A 172
LYS A 225
GLU A 226
LEU A 161
 None
 1.44A 5xooA-1d9zA:
0.0		 5xooA-1d9zA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 7 ILE A 422
PRO A 420
ILE A 519
THR A 451
 None
 0.77A 6cduF-1d9zA:
2.8
6cduG-1d9zA:
3.0		 6cduF-1d9zA:
19.51
6cduG-1d9zA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		4 / 8 ILE A 422
PRO A 420
ILE A 519
THR A 451
 None
 0.76A 6cduG-1d9zA:
3.0
6cduH-1d9zA:
2.9		 6cduG-1d9zA:
19.51
6cduH-1d9zA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1d9z EXCINUCLEASE UVRABC
COMPONENT UVRB
([Bacillus]
caldotenax) 		3 / 3 LYS A  67
SER A 143
SER A  91
 None
 1.13A 6gbfA-1d9zA:
0.0		 6gbfA-1d9zA:
22.43