SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dbi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 ALA A 205
THR A  18
ALA A  94
ALA A 237
ILE A 253
 None
 1.21A 2nyrA-1dbiA:
undetectable		 2nyrA-1dbiA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		4 / 5 LEU A 133
ASP A 138
ALA A 160
ILE A 116
 None
 1.08A 2qhfA-1dbiA:
0.0		 2qhfA-1dbiA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		6 / 12 ALA A 205
PRO A 206
VAL A 185
ILE A 260
ASP A 258
PHE A 267
 None
 1.22A 2v95A-1dbiA:
0.0		 2v95A-1dbiA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 9 ALA A 160
ALA A 162
SER A 195
SER A 229
ALA A 228
 None
 1.27A 2vh3A-1dbiA:
undetectable		 2vh3A-1dbiA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		3 / 3 ASP A  65
ASP A  61
ASP A  43
 CA  A 703 (-4.6A)
None
None
 0.74A 3douA-1dbiA:
undetectable		 3douA-1dbiA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 GLY A  14
ASN A  17
ILE A  90
GLY A  78
HIS A  75
 None
 1.15A 3eeyA-1dbiA:
undetectable		 3eeyA-1dbiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 GLY A  14
ASN A  17
ILE A  90
GLY A  78
HIS A  75
 None
 1.14A 3eeyB-1dbiA:
undetectable		 3eeyB-1dbiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 GLY A  14
ASN A  17
ILE A  90
GLY A  78
HIS A  75
 None
 1.14A 3eeyC-1dbiA:
2.1		 3eeyC-1dbiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 GLY A  14
ASN A  17
ILE A  90
GLY A  78
HIS A  75
 None
 1.15A 3eeyD-1dbiA:
undetectable		 3eeyD-1dbiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 GLY A  14
ASN A  17
ILE A  90
GLY A  78
HIS A  75
 None
 1.13A 3eeyE-1dbiA:
undetectable		 3eeyE-1dbiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 GLY A  14
ASN A  17
ILE A  90
GLY A  78
HIS A  75
 None
 1.13A 3eeyH-1dbiA:
undetectable		 3eeyH-1dbiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 GLY A  14
ASN A  17
ILE A  90
GLY A  78
HIS A  75
 None
 1.13A 3eeyI-1dbiA:
undetectable		 3eeyI-1dbiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 GLY A  14
ASN A  17
ILE A  90
GLY A  78
HIS A  75
 None
 1.12A 3eeyJ-1dbiA:
undetectable		 3eeyJ-1dbiA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 ALA A 236
ALA A 233
ALA A 237
VAL A 148
ILE A 120
 None
 0.97A 3h0aA-1dbiA:
undetectable		 3h0aA-1dbiA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		4 / 8 GLY A 183
ILE A 210
MET A 222
PHE A 194
 None
 0.69A 3ko0B-1dbiA:
undetectable
3ko0J-1dbiA:
undetectable		 3ko0B-1dbiA:
15.02
3ko0J-1dbiA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		4 / 8 GLY A 183
ILE A 210
MET A 222
PHE A 194
 None
 0.70A 3ko0K-1dbiA:
undetectable
3ko0S-1dbiA:
undetectable		 3ko0K-1dbiA:
15.02
3ko0S-1dbiA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 10 ILE A  90
ASP A  48
VAL A 211
ILE A 210
ILE A  79
 None
CA  A 701 (-2.2A)
None
None
None
 1.42A 3kpbD-1dbiA:
undetectable		 3kpbD-1dbiA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 10 SER A 229
ALA A 205
ILE A 210
ALA A  80
ILE A  79
 None
 0.98A 4lbgA-1dbiA:
4.4		 4lbgA-1dbiA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 9 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.15A 4mm5A-1dbiA:
0.0		 4mm5A-1dbiA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.04A 4mm8A-1dbiA:
0.1		 4mm8A-1dbiA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 11 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.09A 4mm9A-1dbiA:
0.0		 4mm9A-1dbiA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 9 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.07A 4mmbA-1dbiA:
0.0		 4mmbA-1dbiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 10 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.03A 4mmdA-1dbiA:
0.1		 4mmdA-1dbiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.01A 4mmdB-1dbiA:
0.2		 4mmdB-1dbiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 9 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.04A 4mmeA-1dbiA:
undetectable		 4mmeA-1dbiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 9 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.01A 4mmeB-1dbiA:
undetectable		 4mmeB-1dbiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 9 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.03A 4mmfA-1dbiA:
0.2		 4mmfA-1dbiA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 9 ASP A  48
VAL A 211
ALA A 220
TYR A 219
GLY A  92
 CA  A 701 (-2.2A)
None
None
None
None
 1.02A 4mmfB-1dbiA:
undetectable		 4mmfB-1dbiA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		4 / 8 ALA A 151
ALA A 123
ALA A 119
ALA A 117
 None
 0.78A 4twdF-1dbiA:
0.0
4twdG-1dbiA:
0.0
4twdH-1dbiA:
0.0
4twdI-1dbiA:
0.0
4twdJ-1dbiA:
0.0		 4twdF-1dbiA:
23.19
4twdG-1dbiA:
23.19
4twdH-1dbiA:
23.19
4twdI-1dbiA:
23.19
4twdJ-1dbiA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		4 / 6 TYR A 219
HIS A  46
ARG A 218
ASN A 217
 None
 1.18A 4zbqA-1dbiA:
undetectable		 4zbqA-1dbiA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		4 / 8 LEU A 235
ASN A 276
ALA A 277
GLU A 254
 None
 0.87A 4zbqA-1dbiA:
undetectable		 4zbqA-1dbiA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		3 / 3 ALA A 119
TYR A 122
PRO A  66
 None
 0.72A 4zdyA-1dbiA:
0.0		 4zdyA-1dbiA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		4 / 7 ASP A   5
ILE A  90
GLY A  78
THR A  84
 CA  A 701 (-3.2A)
None
None
None
 1.05A 4zxiA-1dbiA:
2.6		 4zxiA-1dbiA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		4 / 7 TRP A  24
PRO A  95
THR A  97
SER A 241
 None
 1.38A 5b6iA-1dbiA:
5.8		 5b6iA-1dbiA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 11 THR A  74
ALA A  77
GLY A  78
ALA A  82
ASP A   5
 None
None
None
CA  A 701 ( 4.9A)
CA  A 701 (-3.2A)
 1.33A 5bxnV-1dbiA:
undetectable
5bxnW-1dbiA:
undetectable		 5bxnV-1dbiA:
22.45
5bxnW-1dbiA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8T_B_SAMB605_0
(GUANINE-N7
METHYLTRANSFERASE)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 11 GLY A  89
ASP A   5
ALA A  91
TYR A  11
VAL A 211
 CA  A 701 ( 4.4A)
CA  A 701 (-3.2A)
None
None
None
 1.37A 5c8tB-1dbiA:
1.7		 5c8tB-1dbiA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		4 / 6 TYR A 122
ILE A 131
VAL A 102
ALA A  36
 None
 0.83A 5cu6A-1dbiA:
undetectable		 5cu6A-1dbiA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 HIS A  75
GLY A  73
HIS A 231
ALA A 233
SER A 195
 None
 1.10A 5igyA-1dbiA:
0.0		 5igyA-1dbiA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 THR A  74
ALA A  77
GLY A  78
ALA A  82
ASP A   5
 None
None
None
CA  A 701 ( 4.9A)
CA  A 701 (-3.2A)
 1.35A 5l5zH-1dbiA:
undetectable
5l5zI-1dbiA:
undetectable		 5l5zH-1dbiA:
22.45
5l5zI-1dbiA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1dbi AK.1 SERINE PROTEASE
(Bacillus
sp.
Ak1) 		5 / 12 THR A  74
ALA A  77
GLY A  78
ALA A  82
ASP A   5
 None
None
None
CA  A 701 ( 4.9A)
CA  A 701 (-3.2A)
 1.35A 5l5zV-1dbiA:
undetectable
5l5zW-1dbiA:
undetectable		 5l5zV-1dbiA:
22.45
5l5zW-1dbiA:
19.66