SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dbv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 7 ASN O 313
TYR O 317
ASN O 152
TYR O 311
 NAD  O 336 (-4.2A)
NAD  O 336 (-3.7A)
None
None
 0.92A 1dssG-1dbvO:
50.5		 1dssG-1dbvO:
53.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		7 / 7 SER O 148
THR O 150
ASN O 152
CYH O 153
TYR O 311
ASN O 313
TYR O 317
 SO4  O 339 (-2.9A)
SO4  O 339 ( 4.5A)
None
None
None
NAD  O 336 (-4.2A)
NAD  O 336 (-3.7A)
 0.24A 1dssG-1dbvO:
50.5		 1dssG-1dbvO:
53.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 8 ASN O 313
TYR O 317
ASN O 152
TYR O 311
 NAD  O 336 (-4.2A)
NAD  O 336 (-3.7A)
None
None
 0.91A 1dssR-1dbvO:
50.4		 1dssR-1dbvO:
53.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		8 / 8 SER O 148
THR O 150
ASN O 152
CYH O 153
HIS O 176
TYR O 311
ASN O 313
TYR O 317
 SO4  O 339 (-2.9A)
SO4  O 339 ( 4.5A)
None
None
None
None
NAD  O 336 (-4.2A)
NAD  O 336 (-3.7A)
 0.35A 1dssR-1dbvO:
50.4		 1dssR-1dbvO:
53.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 7 THR O 179
GLU O 314
SER O 238
VAL O 240
 SO4  O 338 (-3.5A)
None
None
None
 1.01A 1tv8A-1dbvO:
undetectable		 1tv8A-1dbvO:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 7 THR O 179
GLU O 314
SER O 238
VAL O 240
 SO4  O 338 (-3.5A)
None
None
None
 1.09A 1tv8B-1dbvO:
undetectable		 1tv8B-1dbvO:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 8 THR O 179
GLU O 314
SER O 238
VAL O 240
 SO4  O 338 (-3.5A)
None
None
None
 1.05A 2fb2A-1dbvO:
undetectable		 2fb2A-1dbvO:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 5 LEU O 242
LEU O 259
CYH O 153
THR O 150
 None
None
None
SO4  O 339 ( 4.5A)
 1.29A 2oaxD-1dbvO:
0.0		 2oaxD-1dbvO:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 12 GLY O   4
ALA O 111
LEU O  82
VAL O   1
VAL O  93
 None
 1.06A 2yvlA-1dbvO:
4.7		 2yvlA-1dbvO:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 12 GLY O   4
ALA O 111
LEU O  82
VAL O   1
VAL O  93
 None
 1.07A 2yvlB-1dbvO:
4.3		 2yvlB-1dbvO:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 12 GLY O   4
ALA O 111
LEU O  82
VAL O   1
VAL O  93
 None
 1.05A 2yvlD-1dbvO:
4.7		 2yvlD-1dbvO:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU O 109
ALA O 105
HIS O 141
LEU O 333
ALA O 113
 None
 1.12A 3dfrA-1dbvO:
undetectable		 3dfrA-1dbvO:
20.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 8 ASN O 313
TYR O 317
ASN O 152
TYR O 311
 NAD  O 336 (-4.2A)
NAD  O 336 (-3.7A)
None
None
 0.94A 3dmtC-1dbvO:
48.5		 3dmtC-1dbvO:
51.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		8 / 8 SER O 148
THR O 150
ASN O 152
CYH O 153
HIS O 176
TYR O 311
ASN O 313
TYR O 317
 SO4  O 339 (-2.9A)
SO4  O 339 ( 4.5A)
None
None
None
None
NAD  O 336 (-4.2A)
NAD  O 336 (-3.7A)
 0.31A 3dmtC-1dbvO:
48.5		 3dmtC-1dbvO:
51.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 7 THR O 291
SER O 296
VAL O 308
VAL O 239
 None
 0.68A 3em0B-1dbvO:
undetectable		 3em0B-1dbvO:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 8 GLY O 112
ALA O 113
ASP O  90
GLY O   4
VAL O 143
 None
 1.31A 3em6A-1dbvO:
undetectable		 3em6A-1dbvO:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 7 LEU O 333
ILE O 144
VAL O 321
LEU O 324
 None
 0.60A 3r9vA-1dbvO:
0.0
3r9vB-1dbvO:
0.0		 3r9vA-1dbvO:
22.69
3r9vB-1dbvO:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		3 / 3 ASN O 236
ASP O 312
ASN O 313
 None
None
NAD  O 336 (-4.2A)
 0.72A 4agaA-1dbvO:
undetectable		 4agaA-1dbvO:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 8 ASN O 152
LEU O 324
ASN O 146
ILE O 144
 None
 1.07A 4k0bA-1dbvO:
0.0		 4k0bA-1dbvO:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 8 ASN O 152
LEU O 324
ASN O 146
ILE O 144
 None
 1.04A 4l7iA-1dbvO:
0.0		 4l7iA-1dbvO:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 12 PHE O 157
VAL O 160
THR O 208
SER O 148
GLY O 209
 None
None
SO4  O 339 (-4.1A)
SO4  O 339 (-2.9A)
SO4  O 339 (-4.1A)
 1.47A 4olfA-1dbvO:
4.3		 4olfA-1dbvO:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 11 SER O 148
LEU O 154
PRO O 156
VAL O 129
THR O 127
 SO4  O 339 (-2.9A)
None
None
None
None
 1.14A 4uuuB-1dbvO:
undetectable		 4uuuB-1dbvO:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 10 LEU O 221
LEU O 225
THR O 151
LEU O 154
LEU O 218
 None
 1.03A 4z91A-1dbvO:
0.0
4z91B-1dbvO:
0.0
4z91C-1dbvO:
0.0
4z91D-1dbvO:
0.0
4z91E-1dbvO:
0.0		 4z91A-1dbvO:
21.49
4z91B-1dbvO:
21.49
4z91C-1dbvO:
21.49
4z91D-1dbvO:
21.49
4z91E-1dbvO:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 11 VAL O   1
VAL O   3
ILE O 144
TYR O 137
LEU O 333
 None
 1.00A 5e4dB-1dbvO:
0.0		 5e4dB-1dbvO:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		3 / 3 THR O 151
ALA O 147
ASN O 152
 None
 0.60A 5ersA-1dbvO:
undetectable		 5ersA-1dbvO:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU O 267
PHE O 157
VAL O 160
THR O 208
SER O 148
 None
None
None
SO4  O 339 (-4.1A)
SO4  O 339 (-2.9A)
 1.27A 5xiqA-1dbvO:
4.8		 5xiqA-1dbvO:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU O 267
PHE O 157
VAL O 160
THR O 208
SER O 148
 None
None
None
SO4  O 339 (-4.1A)
SO4  O 339 (-2.9A)
 1.19A 5xiqB-1dbvO:
4.8		 5xiqB-1dbvO:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Geobacillus
stearothermophil
us) 		4 / 6 ALA O 272
SER O 289
GLY O 316
THR O 315
 None
 0.88A 6f8cA-1dbvO:
0.0		 6f8cA-1dbvO:
13.97