SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 1dby CHLOROPLAST
THIOREDOXIN M CH2
(Chlamydomonas
reinhardtii) 		5 / 10 LEU A  57
ILE A  37
GLY A  91
ILE A  90
VAL A  24
 None
 1.14A 1d4yA-1dbyA:
undetectable		 1d4yA-1dbyA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1dby CHLOROPLAST
THIOREDOXIN M CH2
(Chlamydomonas
reinhardtii) 		5 / 12 VAL A  41
ILE A  89
THR A  76
VAL A 102
LEU A  52
 None
 1.05A 2jn3A-1dbyA:
0.0		 2jn3A-1dbyA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 1dby CHLOROPLAST
THIOREDOXIN M CH2
(Chlamydomonas
reinhardtii) 		5 / 9 LEU A  57
ILE A  37
GLY A  91
ILE A  90
VAL A  24
 None
 0.94A 2r5qA-1dbyA:
undetectable		 2r5qA-1dbyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 1dby CHLOROPLAST
THIOREDOXIN M CH2
(Chlamydomonas
reinhardtii) 		5 / 9 LEU A  57
ILE A  37
GLY A  91
ILE A  90
VAL A  24
 None
 0.94A 2r5qC-1dbyA:
undetectable		 2r5qC-1dbyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 1dby CHLOROPLAST
THIOREDOXIN M CH2
(Chlamydomonas
reinhardtii) 		4 / 8 VAL A  14
VAL A  65
TYR A  69
VAL A  24
 None
 0.99A 2y05A-1dbyA:
undetectable
2y05B-1dbyA:
undetectable		 2y05A-1dbyA:
16.88
2y05B-1dbyA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 1dby CHLOROPLAST
THIOREDOXIN M CH2
(Chlamydomonas
reinhardtii) 		5 / 10 LEU A  57
ILE A  37
GLY A  91
ILE A  90
VAL A  24
 None
 0.99A 5kr1A-1dbyA:
undetectable		 5kr1A-1dbyA:
23.85