SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 1dc9 INTESTINAL FATTY
ACID BINDING PROTEIN
(Rattus
norvegicus) 		6 / 12 GLU A  51
TYR A  70
THR A  76
LEU A  78
LEU A 102
TYR A 117
 None
 1.06A 2mjiA-1dc9A:
15.1		 2mjiA-1dc9A:
80.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 1dc9 INTESTINAL FATTY
ACID BINDING PROTEIN
(Rattus
norvegicus) 		5 / 12 TYR A  14
MET A  21
GLU A  51
LEU A 102
TYR A 117
 None
 1.17A 2mjiA-1dc9A:
15.1		 2mjiA-1dc9A:
80.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 1dc9 INTESTINAL FATTY
ACID BINDING PROTEIN
(Rattus
norvegicus) 		5 / 12 TYR A 117
PHE A  17
LEU A  72
LEU A 102
TYR A  14
 None
 1.18A 4j03A-1dc9A:
undetectable		 4j03A-1dc9A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dc9 INTESTINAL FATTY
ACID BINDING PROTEIN
(Rattus
norvegicus) 		4 / 7 ARG A  95
VAL A 122
PHE A  17
GLU A  19
 None
 1.25A 4jseA-1dc9A:
undetectable
4jseB-1dc9A:
undetectable		 4jseA-1dc9A:
15.17
4jseB-1dc9A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1dc9 INTESTINAL FATTY
ACID BINDING PROTEIN
(Rattus
norvegicus) 		4 / 7 PHE A  17
GLU A  19
ARG A  95
VAL A 122
 None
 1.23A 4jseA-1dc9A:
undetectable
4jseB-1dc9A:
0.0		 4jseA-1dc9A:
15.17
4jseB-1dc9A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 1dc9 INTESTINAL FATTY
ACID BINDING PROTEIN
(Rattus
norvegicus) 		3 / 3 VAL A  96
GLY A  99
LYS A  94
 None
 0.73A 4k50A-1dc9A:
undetectable		 4k50A-1dc9A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 1dc9 INTESTINAL FATTY
ACID BINDING PROTEIN
(Rattus
norvegicus) 		3 / 3 VAL A  96
GLY A  99
LYS A  94
 None
 0.69A 4k50E-1dc9A:
undetectable		 4k50E-1dc9A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 1dc9 INTESTINAL FATTY
ACID BINDING PROTEIN
(Rattus
norvegicus) 		3 / 3 VAL A  96
GLY A  99
LYS A  94
 None
 0.74A 4k50I-1dc9A:
undetectable		 4k50I-1dc9A:
15.56