SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dct'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 11 PRO A 172
TYR A 169
ASP A 146
LEU A 142
TYR A 147
 None
 1.34A 1c3sA-1dctA:
2.4		 1c3sA-1dctA:
22.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		6 / 8 PHE A   7
GLU A  29
ASP A  50
ILE A  51
PRO A  70
LEU A  90
 None
 0.76A 1hmyA-1dctA:
27.1		 1hmyA-1dctA:
33.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 11 GLN A  18
GLY A  12
GLY A  16
ILE A  24
GLY A   9
 None
 1.12A 1jg3A-1dctA:
4.8		 1jg3A-1dctA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 11 GLN A  18
GLY A  12
GLY A  16
ILE A  24
GLY A   9
 None
 1.11A 1jg3B-1dctA:
6.1		 1jg3B-1dctA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 GLY A   9
ASP A  31
ASP A  50
ILE A  51
PRO A  70
 None
 0.74A 1qaoA-1dctA:
8.7		 1qaoA-1dctA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 GLY A  11
GLY A  12
ASP A  31
ASP A  50
PRO A  70
 None
 0.55A 1sqfA-1dctA:
9.5		 1sqfA-1dctA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_A_CIOA603_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 LEU A  90
ILE A  97
PHE A  59
SER A   5
PHE A   7
 None
 1.18A 1xomA-1dctA:
undetectable		 1xomA-1dctA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_B_CIOB601_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 LEU A  90
ILE A  97
PHE A  59
SER A   5
PHE A   7
 None
 1.17A 1xomB-1dctA:
undetectable		 1xomB-1dctA:
19.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		7 / 12 PHE A   7
GLY A   9
GLY A  12
ASN A  28
ASP A  31
ASP A  50
ILE A  51
 None
 0.70A 2hmyB-1dctA:
27.2		 2hmyB-1dctA:
33.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		8 / 12 PHE A   7
GLY A   9
GLY A  12
ASN A  28
ASP A  31
ILE A  51
PRO A  70
LEU A  90
 None
 0.67A 2hmyB-1dctA:
27.2		 2hmyB-1dctA:
33.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		7 / 12 PHE A   7
GLY A   9
GLY A  12
ASN A  28
ASP A  50
ILE A  51
VAL A 308
 None
 0.86A 2hmyB-1dctA:
27.2		 2hmyB-1dctA:
33.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		8 / 12 PHE A   7
GLY A   9
GLY A  12
ASN A  28
ILE A  51
PRO A  70
LEU A  90
VAL A 308
 None
 0.86A 2hmyB-1dctA:
27.2		 2hmyB-1dctA:
33.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 PHE A   7
GLY A  11
ILE A  51
PRO A  70
LEU A  90
 None
 0.88A 2hmyB-1dctA:
27.2		 2hmyB-1dctA:
33.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 11 LEU A 142
VAL A 149
GLN A 151
ILE A 316
LEU A  13
 None
 1.22A 2qeiA-1dctA:
undetectable		 2qeiA-1dctA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		9 / 12 PHE A   7
GLY A   9
GLY A  12
LEU A  13
PRO A  70
LEU A  90
ASN A 306
ALA A 307
VAL A 308
 None
 0.74A 3av6A-1dctA:
17.9		 3av6A-1dctA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		6 / 12 PHE A   7
GLY A  11
LEU A  13
PRO A  70
LEU A  90
ASN A 306
 None
 1.28A 3av6A-1dctA:
17.9		 3av6A-1dctA:
13.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		6 / 12 PHE A   7
GLY A  11
ILE A  51
PRO A  70
LEU A  90
ASN A 306
 None
 1.18A 3eeoA-1dctA:
32.7		 3eeoA-1dctA:
33.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		9 / 12 PHE A   7
GLY A  12
ASN A  28
ASP A  31
ASP A  50
ILE A  51
PRO A  70
LEU A  90
ASN A 306
 None
 0.90A 3eeoA-1dctA:
32.7		 3eeoA-1dctA:
33.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		4 / 6 ILE A  95
TYR A 135
LYS A 102
ILE A  97
 None
 1.13A 3eteA-1dctA:
3.7
3eteE-1dctA:
3.8		 3eteA-1dctA:
22.52
3eteE-1dctA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		4 / 7 LYS A 102
ILE A  97
ILE A  95
TYR A 135
 None
 1.13A 3eteD-1dctA:
3.7
3eteF-1dctA:
4.0		 3eteD-1dctA:
22.52
3eteF-1dctA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 GLY A  16
ALA A 317
THR A 319
ILE A 159
ILE A 139
 None
 1.14A 3ld6A-1dctA:
0.0		 3ld6A-1dctA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		4 / 7 ASN A 226
TYR A 272
ARG A 273
ALA A 251
 None
 1.01A 3twpC-1dctA:
3.5		 3twpC-1dctA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 11 GLY A   9
ASP A  31
ASP A  50
PRO A  70
LEU A  90
 None
 0.99A 3v8vB-1dctA:
8.3		 3v8vB-1dctA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 11 ALA A 313
LEU A  13
PHE A  17
TYR A 169
ILE A 140
 None
 1.15A 4claA-1dctA:
0.4		 4claA-1dctA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 GLY A  11
GLY A  12
ASN A  28
ASP A  50
PRO A  70
 None
 0.86A 4fp9D-1dctA:
8.2		 4fp9D-1dctA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 GLY A  11
GLY A  12
ASN A  28
ASP A  50
PRO A  70
 None
 0.85A 4fzvA-1dctA:
8.5		 4fzvA-1dctA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		3 / 3 GLU A  29
ASP A  31
ASP A  50
 None
 0.44A 4gc9A-1dctA:
6.2		 4gc9A-1dctA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		4 / 8 ASP A  14
ALA A  44
TYR A  38
SER A   8
 None
 1.05A 4l7iB-1dctA:
undetectable		 4l7iB-1dctA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		4 / 7 SER A   5
GLY A  11
ALA A  10
SER A  33
 None
 0.90A 4r1zB-1dctA:
undetectable		 4r1zB-1dctA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 ALA A  27
GLY A  11
ALA A 108
GLY A  68
TYR A  94
 None
 1.12A 4r29B-1dctA:
1.1		 4r29B-1dctA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 ASP A  50
PRO A  70
PHE A   7
GLY A   9
GLU A  29
 None
 0.66A 5hfjD-1dctA:
2.5		 5hfjD-1dctA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 11 PHE A   7
GLY A   9
GLU A  29
ASP A  50
PRO A  70
 None
 0.90A 5hjiA-1dctA:
4.6		 5hjiA-1dctA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 ASP A  50
ILE A  51
PRO A  70
LEU A  90
PHE A   7
 None
 1.01A 5il1A-1dctA:
0.9		 5il1A-1dctA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		5 / 12 ASP A  50
ILE A  51
PRO A  70
LEU A  90
PHE A   7
 None
 1.00A 5k7uA-1dctA:
5.2		 5k7uA-1dctA:
22.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 1dct PROTEIN
(MODIFICATION
METHYLASE HAEIII)
(Haemophilus
influenzae) 		9 / 12 PHE A   7
GLY A   9
GLY A  12
ASN A  28
ASP A  31
ASP A  50
ILE A  51
ASN A 306
VAL A 308
 None
 0.81A 6mhtA-1dctA:
29.5		 6mhtA-1dctA:
33.24