SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dcz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1dcz TRANSCARBOXYLASE
1.3S SUBUNIT
(Propionibacteriu
m
freudenreichii) 		5 / 7 VAL A 102
ILE A 120
ALA A  96
VAL A  76
GLY A 123
 None
 1.24A 2xrzB-1dczA:
undetectable		 2xrzB-1dczA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1dcz TRANSCARBOXYLASE
1.3S SUBUNIT
(Propionibacteriu
m
freudenreichii) 		5 / 8 VAL A 107
LEU A 119
ILE A  68
VAL A  65
LEU A  85
 None
 1.28A 3kp6A-1dczA:
undetectable
3kp6B-1dczA:
undetectable		 3kp6A-1dczA:
23.73
3kp6B-1dczA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 1dcz TRANSCARBOXYLASE
1.3S SUBUNIT
(Propionibacteriu
m
freudenreichii) 		6 / 11 THR A  92
ALA A  87
LEU A  85
THR A  64
VAL A 113
LEU A  83
 None
 1.47A 4g1bB-1dczA:
undetectable		 4g1bB-1dczA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1dcz TRANSCARBOXYLASE
1.3S SUBUNIT
(Propionibacteriu
m
freudenreichii) 		5 / 10 THR A  75
LEU A  69
ALA A  96
ILE A 122
GLU A  93
 None
 1.42A 4pe5A-1dczA:
undetectable
4pe5B-1dczA:
undetectable		 4pe5A-1dczA:
7.24
4pe5B-1dczA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_C_QELC939_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1dcz TRANSCARBOXYLASE
1.3S SUBUNIT
(Propionibacteriu
m
freudenreichii) 		5 / 10 THR A  75
LEU A  69
ALA A  96
ILE A 122
GLU A  93
 None
 1.46A 4pe5C-1dczA:
undetectable
4pe5D-1dczA:
undetectable		 4pe5C-1dczA:
7.24
4pe5D-1dczA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1dcz TRANSCARBOXYLASE
1.3S SUBUNIT
(Propionibacteriu
m
freudenreichii) 		5 / 11 THR A  75
LEU A  69
ALA A  96
ILE A 122
GLU A  93
 None
 1.49A 5ewjA-1dczA:
undetectable
5ewjB-1dczA:
undetectable		 5ewjA-1dczA:
14.40
5ewjB-1dczA:
13.26