SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ddb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1ddb PROTEIN (BID)
(Mus
musculus) 		3 / 3 HIS A 162
ASP A  98
ASN A 100
 None
 0.77A 1wg8B-1ddbA:
undetectable		 1wg8B-1ddbA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 1ddb PROTEIN (BID)
(Mus
musculus) 		3 / 3 LEU A 127
HIS A 172
LYS A 123
 None
 1.02A 1y7iA-1ddbA:
undetectable		 1y7iA-1ddbA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_B_SPMB1433_1
(NITROALKANE OXIDASE)		 1ddb PROTEIN (BID)
(Mus
musculus) 		5 / 11 GLU A  34
VAL A 170
ALA A 160
LEU A  25
VAL A  21
 None
 1.49A 2c12B-1ddbA:
0.0		 2c12B-1ddbA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_D_SPMD1434_1
(NITROALKANE OXIDASE)		 1ddb PROTEIN (BID)
(Mus
musculus) 		5 / 10 GLU A  34
VAL A 170
ALA A 160
LEU A  25
VAL A  21
 None
 1.49A 2c12D-1ddbA:
0.0		 2c12D-1ddbA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 1ddb PROTEIN (BID)
(Mus
musculus) 		4 / 6 THR A 152
PHE A  24
LEU A  90
ASP A  95
 None
 0.80A 2wm3A-1ddbA:
undetectable		 2wm3A-1ddbA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 1ddb PROTEIN (BID)
(Mus
musculus) 		5 / 12 SER A  28
LEU A  25
THR A  31
ALA A 156
THR A 174
 None
 1.12A 3a35A-1ddbA:
undetectable		 3a35A-1ddbA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 1ddb PROTEIN (BID)
(Mus
musculus) 		5 / 12 SER A  28
LEU A  25
THR A  31
ALA A 156
THR A 174
 None
 1.15A 3a35B-1ddbA:
undetectable		 3a35B-1ddbA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 1ddb PROTEIN (BID)
(Mus
musculus) 		5 / 12 SER A  28
LEU A  25
THR A  31
ALA A 156
THR A 174
 None
 1.13A 3a3bA-1ddbA:
undetectable		 3a3bA-1ddbA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1ddb PROTEIN (BID)
(Mus
musculus) 		4 / 4 LEU A  38
ALA A 160
VAL A 159
PRO A 164
 None
 1.15A 3gv1B-1ddbA:
undetectable		 3gv1B-1ddbA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 1ddb PROTEIN (BID)
(Mus
musculus) 		4 / 6 LEU A  38
GLN A  33
LEU A  35
GLU A  34
 None
 1.08A 3h5gB-1ddbA:
undetectable
3h5gC-1ddbA:
undetectable		 3h5gB-1ddbA:
10.26
3h5gC-1ddbA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1ddb PROTEIN (BID)
(Mus
musculus) 		6 / 12 GLU A  41
ASP A  18
GLU A  36
GLY A  23
ALA A  87
ILE A 178
 None
 1.49A 4xe5A-1ddbA:
undetectable		 4xe5A-1ddbA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ddb PROTEIN (BID)
(Mus
musculus) 		4 / 7 GLU A  81
ILE A  16
LEU A 149
ILE A  86
 None
 0.92A 4xumA-1ddbA:
undetectable		 4xumA-1ddbA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1ddb PROTEIN (BID)
(Mus
musculus) 		3 / 3 ALA A 137
GLN A 108
THR A 104
 None
 0.72A 5n0oA-1ddbA:
0.0		 5n0oA-1ddbA:
20.50