SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ddh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		3 / 3 ASP A 102
LEU A 110
HIS A 263
 None
 0.78A 1qknA-1ddhA:
0.0		 1qknA-1ddhA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		4 / 5 TYR A 113
SER A   4
ARG A   6
HIS A 263
 None
 1.50A 1s19A-1ddhA:
0.0		 1s19A-1ddhA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		3 / 3 TRP A 167
GLU A  63
TYR A  59
 None
 0.98A 2a3aA-1ddhA:
undetectable		 2a3aA-1ddhA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		3 / 3 TRP A  97
ALA A  11
VAL A   9
 None
 0.74A 2izqA-1ddhA:
undetectable
2izqB-1ddhA:
undetectable		 2izqA-1ddhA:
4.14
2izqB-1ddhA:
4.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		5 / 12 GLU A  63
ARG A  66
ILE A  52
VAL A  34
GLU A  24
 None
 1.48A 2qeoA-1ddhA:
0.0		 2qeoA-1ddhA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		4 / 7 GLU A  24
TYR A 159
PHE A  74
TYR A  22
 None
 1.33A 3ku9B-1ddhA:
undetectable		 3ku9B-1ddhA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		3 / 3 ALA A  11
VAL A   9
TRP A  97
 None
 0.73A 3l8lA-1ddhA:
undetectable
3l8lB-1ddhA:
undetectable		 3l8lA-1ddhA:
4.14
3l8lB-1ddhA:
4.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		3 / 3 ALA A  11
VAL A   9
TRP A  97
 None
 0.82A 3l8lC-1ddhA:
undetectable
3l8lD-1ddhA:
undetectable		 3l8lC-1ddhA:
4.14
3l8lD-1ddhA:
4.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR A 171
TYR A   7
GLU A 166
 None
 0.23A 3pfgA-1ddhA:
undetectable		 3pfgA-1ddhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT2_A_ASDA1490_1
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		5 / 10 GLU A 166
VAL A 103
TYR A 159
PHE A  33
TYR A   7
 None
 1.50A 4at2A-1ddhA:
0.0		 4at2A-1ddhA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 1ddh MHC CLASS I H-2DD
HEAVY CHAIN
(Mus
musculus) 		4 / 8 SER A  73
ASP A  77
PHE A 116
ASN A  70
 None
 1.12A 5l1fA-1ddhA:
undetectable
5l1fB-1ddhA:
undetectable		 5l1fA-1ddhA:
14.95
5l1fB-1ddhA:
14.95