SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ddl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_B_MTXB609_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	1ddl	DESMODIUM YELLOW MOTTLE VIRUS (Desmodium yellow mottle virus)	5 / 12	ALA A 69 LEU A 71 LEU A 59 SER A 57 THR A 150	None	1.22A	2oipB-1ddlA: undetectable	2oipB-1ddlA: 15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	1ddl	DESMODIUM YELLOW MOTTLE VIRUS (Desmodium yellow mottle virus)	5 / 12	ALA A 69 LEU A 71 LEU A 59 SER A 57 THR A 150	None	1.08A	2oipC-1ddlA: undetectable	2oipC-1ddlA: 15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_D_MTXD617_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	1ddl	DESMODIUM YELLOW MOTTLE VIRUS (Desmodium yellow mottle virus)	5 / 12	ALA A 69 LEU A 71 LEU A 59 SER A 57 THR A 150	None	1.19A	2oipD-1ddlA: undetectable	2oipD-1ddlA: 15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_E_MTXE621_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	1ddl	DESMODIUM YELLOW MOTTLE VIRUS (Desmodium yellow mottle virus)	5 / 12	ALA A 69 LEU A 71 LEU A 59 SER A 57 THR A 150	None	1.13A	2oipE-1ddlA: undetectable	2oipE-1ddlA: 15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_A_MTXA605_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	1ddl	DESMODIUM YELLOW MOTTLE VIRUS (Desmodium yellow mottle virus)	5 / 12	ALA A 69 LEU A 71 LEU A 59 SER A 57 THR A 150	None	1.21A	3hj3A-1ddlA: undetectable	3hj3A-1ddlA: 15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_D_MTXD615_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	1ddl	DESMODIUM YELLOW MOTTLE VIRUS (Desmodium yellow mottle virus)	5 / 12	ALA A 69 LEU A 71 LEU A 59 SER A 57 THR A 150	None	1.09A	3hj3D-1ddlA: undetectable	3hj3D-1ddlA: 15.68

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OIP_B_MTXB609_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","1ddl","DESMODIUM YELLOW MOTTLE VIRUS","Desmodium yellow mottle virus",5,"ALA A  69;LEU A  71;LEU A  59;SER A  57;THR A 150","None","1.22A","2oipB-1ddlA:undetectable","2oipB-1ddlA:15.93"],["2OIP_C_MTXC613_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","1ddl","DESMODIUM YELLOW MOTTLE VIRUS","Desmodium yellow mottle virus",5,"ALA A  69;LEU A  71;LEU A  59;SER A  57;THR A 150","None","1.08A","2oipC-1ddlA:undetectable","2oipC-1ddlA:15.93"],["2OIP_D_MTXD617_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","1ddl","DESMODIUM YELLOW MOTTLE VIRUS","Desmodium yellow mottle virus",5,"ALA A  69;LEU A  71;LEU A  59;SER A  57;THR A 150","None","1.19A","2oipD-1ddlA:undetectable","2oipD-1ddlA:15.93"],["2OIP_E_MTXE621_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","1ddl","DESMODIUM YELLOW MOTTLE VIRUS","Desmodium yellow mottle virus",5,"ALA A  69;LEU A  71;LEU A  59;SER A  57;THR A 150","None","1.13A","2oipE-1ddlA:undetectable","2oipE-1ddlA:15.93"],["3HJ3_A_MTXA605_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","1ddl","DESMODIUM YELLOW MOTTLE VIRUS","Desmodium yellow mottle virus",5,"ALA A  69;LEU A  71;LEU A  59;SER A  57;THR A 150","None","1.21A","3hj3A-1ddlA:undetectable","3hj3A-1ddlA:15.68"],["3HJ3_D_MTXD615_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","1ddl","DESMODIUM YELLOW MOTTLE VIRUS","Desmodium yellow mottle virus",5,"ALA A  69;LEU A  71;LEU A  59;SER A  57;THR A 150","None","1.09A","3hj3D-1ddlA:undetectable","3hj3D-1ddlA:15.68"]]