SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ddm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1ddm NUMB PROTEIN
(Drosophila
melanogaster) 		3 / 3 GLY A 159
ASP A 153
SER A 161
 None
 0.63A 2qhfA-1ddmA:
0.0		 2qhfA-1ddmA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 1ddm NUMB PROTEIN
(Drosophila
melanogaster) 		4 / 9 ILE A 144
ALA A 190
VAL A 191
CYH A 150
 None
 1.01A 2vufB-1ddmA:
undetectable		 2vufB-1ddmA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ddm NUMB PROTEIN
(Drosophila
melanogaster) 		4 / 5 LEU A 109
GLY A 176
ILE A 139
VAL A 140
 None
 0.89A 3wriA-1ddmA:
undetectable		 3wriA-1ddmA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ddm NUMB PROTEIN
(Drosophila
melanogaster) 		4 / 5 LEU A 109
GLY A 176
ILE A 139
VAL A 140
 None
 0.89A 3wriB-1ddmA:
undetectable		 3wriB-1ddmA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1ddm NUMB PROTEIN
(Drosophila
melanogaster) 		3 / 3 LEU A 178
ALA A 179
LEU A 106
 None
 0.53A 5uunB-1ddmA:
0.0		 5uunB-1ddmA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1ddm NUMB PROTEIN
(Drosophila
melanogaster) 		4 / 8 LEU A 128
LEU A 178
GLY A 159
TYR A 162
 None
 0.91A 6ce2A-1ddmA:
undetectable		 6ce2A-1ddmA:
20.57