SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ddv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICU_D_NIOD223_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1ddv	GLGF-DOMAIN PROTEIN HOMER (Rattus norvegicus)	4 / 5	GLY A 89 SER A 71 THR A 70 PHE A 74	None	1.14A	1icuC-1ddvA: 0.0 1icuD-1ddvA: 0.0	1icuC-1ddvA: 18.48 1icuD-1ddvA: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICV_B_NIOB702_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1ddv	GLGF-DOMAIN PROTEIN HOMER (Rattus norvegicus)	4 / 5	GLY A 89 SER A 71 THR A 70 PHE A 74	None	1.19A	1icvA-1ddvA: 0.0 1icvB-1ddvA: 0.0	1icvA-1ddvA: 18.48 1icvB-1ddvA: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_B_BEZB525_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1ddv	GLGF-DOMAIN PROTEIN HOMER (Rattus norvegicus)	4 / 5	GLY A 89 SER A 71 THR A 70 PHE A 74	None	1.22A	1kqbA-1ddvA: 0.0 1kqbB-1ddvA: 0.0	1kqbA-1ddvA: 17.70 1kqbB-1ddvA: 17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TZF_B_08DB280_1 (7,8-DIHYDROPTEROATE SYNTHASE)	1ddv	GLGF-DOMAIN PROTEIN HOMER (Rattus norvegicus)	4 / 8	THR A 9 ARG A 10 GLY A 89 PHE A 90	None	1.08A	3tzfB-1ddvA: undetectable	3tzfB-1ddvA: 17.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICU_D_NIOD223_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1ddv","GLGF-DOMAIN PROTEIN HOMER","Rattus norvegicus",4,"GLY A  89;SER A  71;THR A  70;PHE A  74","None","1.14A","1icuC-1ddvA:0.0;1icuD-1ddvA:0.0","1icuC-1ddvA:18.48;1icuD-1ddvA:18.48"],["1ICV_B_NIOB702_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1ddv","GLGF-DOMAIN PROTEIN HOMER","Rattus norvegicus",4,"GLY A  89;SER A  71;THR A  70;PHE A  74","None","1.19A","1icvA-1ddvA:0.0;1icvB-1ddvA:0.0","1icvA-1ddvA:18.48;1icvB-1ddvA:18.48"],["1KQB_B_BEZB525_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1ddv","GLGF-DOMAIN PROTEIN HOMER","Rattus norvegicus",4,"GLY A  89;SER A  71;THR A  70;PHE A  74","None","1.22A","1kqbA-1ddvA:0.0;1kqbB-1ddvA:0.0","1kqbA-1ddvA:17.70;1kqbB-1ddvA:17.70"],["3TZF_B_08DB280_1","7,8-DIHYDROPTEROATE SYNTHASE","1ddv","GLGF-DOMAIN PROTEIN HOMER","Rattus norvegicus",4,"THR A   9;ARG A  10;GLY A  89;PHE A  90","None","1.08A","3tzfB-1ddvA:undetectable","3tzfB-1ddvA:17.95"]]