SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ddz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		6 / 8 CYH A 149
HIS A 205
CYH A 208
GLY A 209
GLY A 210
TYR A 444
 ZN  A   1 (-2.4A)
ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
ZN  A   1 (-4.7A)
None
None
 0.28A 1ekjA-1ddzA:
19.0
1ekjB-1ddzA:
18.5		 1ekjA-1ddzA:
19.38
1ekjB-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		6 / 8 CYH A 403
HIS A 459
CYH A 462
GLY A 463
GLY A 464
TYR A 190
 ZN  A   2 (-2.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-2.2A)
None
None
None
 0.43A 1ekjA-1ddzA:
19.0
1ekjB-1ddzA:
18.5		 1ekjA-1ddzA:
19.38
1ekjB-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 8 TYR A 190
CYH A 403
HIS A 459
CYH A 462
GLY A 463
 None
ZN  A   2 (-2.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-2.2A)
None
 0.35A 1ekjA-1ddzA:
19.0
1ekjB-1ddzA:
18.5		 1ekjA-1ddzA:
19.38
1ekjB-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 8 TYR A 190
CYH A 403
HIS A 459
CYH A 462
GLY A 464
 None
ZN  A   2 (-2.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-2.2A)
None
 0.98A 1ekjA-1ddzA:
19.0
1ekjB-1ddzA:
18.5		 1ekjA-1ddzA:
19.38
1ekjB-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 8 TYR A 444
CYH A 149
HIS A 205
CYH A 208
GLY A 209
 None
ZN  A   1 (-2.4A)
ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
ZN  A   1 (-4.7A)
 0.34A 1ekjA-1ddzA:
19.0
1ekjB-1ddzA:
18.5		 1ekjA-1ddzA:
19.38
1ekjB-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 8 TYR A 444
CYH A 149
HIS A 205
CYH A 208
GLY A 210
 None
ZN  A   1 (-2.4A)
ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
None
 1.07A 1ekjA-1ddzA:
19.0
1ekjB-1ddzA:
18.5		 1ekjA-1ddzA:
19.38
1ekjB-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 7 CYH A 149
HIS A 205
GLY A 209
GLY A 210
TYR A 444
 ZN  A   1 (-2.4A)
ZN  A   1 (-3.2A)
ZN  A   1 (-4.7A)
None
None
 0.36A 1ekjE-1ddzA:
18.7
1ekjF-1ddzA:
18.6		 1ekjE-1ddzA:
19.38
1ekjF-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		4 / 7 CYH A 403
ASP A 405
HIS A 459
GLY A 464
 ZN  A   2 (-2.3A)
ZN  A   2 (-2.8A)
ZN  A   2 (-3.2A)
None
 0.96A 1ekjE-1ddzA:
18.7
1ekjF-1ddzA:
18.6		 1ekjE-1ddzA:
19.38
1ekjF-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 7 CYH A 403
HIS A 459
GLY A 463
GLY A 464
TYR A 190
 ZN  A   2 (-2.3A)
ZN  A   2 (-3.2A)
None
None
None
 0.55A 1ekjE-1ddzA:
18.7
1ekjF-1ddzA:
18.6		 1ekjE-1ddzA:
19.38
1ekjF-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 8 PHE A 168
TYR A 190
CYH A 403
GLY A 463
GLY A 464
 None
None
ZN  A   2 (-2.3A)
None
None
 0.69A 1ekjE-1ddzA:
18.7
1ekjF-1ddzA:
18.6		 1ekjE-1ddzA:
19.38
1ekjF-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 8 PHE A 422
TYR A 444
CYH A 149
GLY A 209
GLY A 210
 None
None
ZN  A   1 (-2.4A)
ZN  A   1 (-4.7A)
None
 0.55A 1ekjE-1ddzA:
18.7
1ekjF-1ddzA:
18.6		 1ekjE-1ddzA:
19.38
1ekjF-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		6 / 8 CYH A 149
HIS A 205
CYH A 208
GLY A 209
GLY A 210
TYR A 444
 ZN  A   1 (-2.4A)
ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
ZN  A   1 (-4.7A)
None
None
 0.36A 1ekjG-1ddzA:
18.6
1ekjH-1ddzA:
19.0		 1ekjG-1ddzA:
19.38
1ekjH-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		6 / 8 CYH A 403
HIS A 459
CYH A 462
GLY A 463
GLY A 464
TYR A 190
 ZN  A   2 (-2.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-2.2A)
None
None
None
 0.51A 1ekjG-1ddzA:
18.6
1ekjH-1ddzA:
19.0		 1ekjG-1ddzA:
19.38
1ekjH-1ddzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 8 ALA A 410
GLY A 402
ILE A 401
ILE A 114
ILE A 414
 None
 1.46A 1hshD-1ddzA:
0.0		 1hshD-1ddzA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		4 / 7 LEU A 222
LEU A 227
TYR A 448
GLN A 443
 None
 0.97A 1kt3A-1ddzA:
0.0		 1kt3A-1ddzA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		4 / 8 TYR A 444
PHE A 422
ALA A 174
HIS A 205
 None
None
None
ZN  A   1 (-3.2A)
 1.09A 1x8vA-1ddzA:
0.0		 1x8vA-1ddzA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		3 / 3 ILE A 432
ILE A 182
LEU A 399
 None
 0.53A 2prgA-1ddzA:
0.0		 2prgA-1ddzA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		3 / 3 SER A 152
GLY A 148
GLY A 204
 None
 0.52A 3bogA-1ddzA:
0.0
3bogC-1ddzA:
undetectable		 3bogA-1ddzA:
undetectable
3bogC-1ddzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		4 / 8 ASN A 172
HIS A 170
ASN A 426
ILE A 401
 None
 1.09A 3kp6A-1ddzA:
0.0
3kp6B-1ddzA:
0.0		 3kp6A-1ddzA:
16.12
3kp6B-1ddzA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		4 / 8 ASN A 426
HIS A 424
ASN A 172
ILE A 147
 None
 1.10A 3kp6A-1ddzA:
0.0
3kp6B-1ddzA:
0.0		 3kp6A-1ddzA:
16.12
3kp6B-1ddzA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 9 ILE A 413
GLY A 402
ILE A 401
ILE A 114
ILE A 414
 None
 0.91A 3s43A-1ddzA:
undetectable		 3s43A-1ddzA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 CYH A 149
HIS A 205
CYH A 208
GLY A 209
ALA A 213
 ZN  A   1 (-2.4A)
ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
ZN  A   1 (-4.7A)
None
 0.31A 3ucjA-1ddzA:
23.4		 3ucjA-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 CYH A 149
HIS A 205
CYH A 208
GLY A 210
ALA A 214
 ZN  A   1 (-2.4A)
ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
None
None
 1.17A 3ucjA-1ddzA:
23.4		 3ucjA-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 CYH A 403
ASP A 405
HIS A 459
GLY A 464
ALA A 468
 ZN  A   2 (-2.3A)
ZN  A   2 (-2.8A)
ZN  A   2 (-3.2A)
None
None
 1.19A 3ucjA-1ddzA:
23.4		 3ucjA-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 CYH A 403
HIS A 459
CYH A 462
GLY A 463
ALA A 467
 ZN  A   2 (-2.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-2.2A)
None
None
 0.38A 3ucjA-1ddzA:
23.4		 3ucjA-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 CYH A 403
HIS A 459
CYH A 462
GLY A 464
ALA A 468
 ZN  A   2 (-2.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-2.2A)
None
None
 1.11A 3ucjA-1ddzA:
23.4		 3ucjA-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 HIS A 205
CYH A 208
GLY A 209
ALA A 211
ALA A 213
 ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
ZN  A   1 (-4.7A)
None
None
 1.23A 3ucjA-1ddzA:
23.4		 3ucjA-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 HIS A 205
CYH A 208
GLY A 210
ALA A 211
ALA A 214
 ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
None
None
None
 1.20A 3ucjA-1ddzA:
23.4		 3ucjA-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 CYH A 149
HIS A 205
CYH A 208
GLY A 209
ALA A 213
 ZN  A   1 (-2.4A)
ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
ZN  A   1 (-4.7A)
None
 0.34A 3ucjB-1ddzA:
24.2		 3ucjB-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 CYH A 149
HIS A 205
CYH A 208
GLY A 210
ALA A 214
 ZN  A   1 (-2.4A)
ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
None
None
 1.18A 3ucjB-1ddzA:
24.2		 3ucjB-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 CYH A 403
HIS A 459
CYH A 462
GLY A 463
ALA A 467
 ZN  A   2 (-2.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-2.2A)
None
None
 0.40A 3ucjB-1ddzA:
24.2		 3ucjB-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 CYH A 403
HIS A 459
CYH A 462
GLY A 464
ALA A 468
 ZN  A   2 (-2.3A)
ZN  A   2 (-3.2A)
ZN  A   2 (-2.2A)
None
None
 1.13A 3ucjB-1ddzA:
24.2		 3ucjB-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 HIS A 205
CYH A 208
GLY A 209
ALA A 211
ALA A 213
 ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
ZN  A   1 (-4.7A)
None
None
 1.21A 3ucjB-1ddzA:
24.2		 3ucjB-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 HIS A 205
CYH A 208
GLY A 210
ALA A 211
ALA A 214
 ZN  A   1 (-3.2A)
ZN  A   1 (-2.3A)
None
None
None
 1.18A 3ucjB-1ddzA:
24.2		 3ucjB-1ddzA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 8 VAL A 197
TYR A 194
ILE A 477
GLN A 189
THR A 269
 None
 1.20A 4ma7A-1ddzA:
undetectable		 4ma7A-1ddzA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 12 LEU A 481
ALA A 404
SER A 406
PRO A 142
LEU A 195
 None
 1.42A 5nd2B-1ddzA:
undetectable		 5nd2B-1ddzA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 GLY A 402
VAL A 455
CYH A 457
VAL A 421
LEU A 550
 None
 0.83A 6czmA-1ddzA:
0.3
6czmC-1ddzA:
undetectable		 6czmA-1ddzA:
20.94
6czmC-1ddzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 9 VAL A 368
VAL A 167
LEU A 296
GLY A 148
CYH A 203
 None
 1.26A 6czmD-1ddzA:
0.0
6czmE-1ddzA:
0.0		 6czmD-1ddzA:
20.94
6czmE-1ddzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 9 VAL A 421
LEU A 550
GLY A 402
VAL A 455
CYH A 457
 None
 0.94A 6czmD-1ddzA:
0.0
6czmE-1ddzA:
0.0		 6czmD-1ddzA:
20.94
6czmE-1ddzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1ddz CARBONIC ANHYDRASE
(Porphyridium
purpureum) 		5 / 10 VAL A 421
LEU A 550
GLY A 402
VAL A 455
CYH A 457
 None
 0.90A 6czmE-1ddzA:
0.0
6czmF-1ddzA:
0.0		 6czmE-1ddzA:
20.94
6czmF-1ddzA:
20.94