SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1de3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 1de3 RIBONUCLEASE
ALPHA-SARCIN
(Aspergillus
giganteus) 		4 / 4 PHE A  71
LYS A  70
ILE A 135
THR A 125
 None
 1.31A 3ia4B-1de3A:
undetectable		 3ia4B-1de3A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1de3 RIBONUCLEASE
ALPHA-SARCIN
(Aspergillus
giganteus) 		4 / 6 VAL A 122
LEU A  94
LEU A  95
HIS A  50
 None
 0.92A 6e43A-1de3A:
undetectable		 6e43A-1de3A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1de3 RIBONUCLEASE
ALPHA-SARCIN
(Aspergillus
giganteus) 		4 / 6 VAL A 122
LEU A  94
LEU A  95
HIS A  50
 None
 0.97A 6e43B-1de3A:
undetectable		 6e43B-1de3A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1de3 RIBONUCLEASE
ALPHA-SARCIN
(Aspergillus
giganteus) 		4 / 6 VAL A 122
LEU A  94
LEU A  95
HIS A  50
 None
 0.96A 6e43C-1de3A:
0.0		 6e43C-1de3A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1de3 RIBONUCLEASE
ALPHA-SARCIN
(Aspergillus
giganteus) 		4 / 6 VAL A 122
LEU A  94
LEU A  95
HIS A  50
 None
 0.97A 6e43D-1de3A:
0.0		 6e43D-1de3A:
15.56