SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1de4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.67A 1usqB-1de4A:
0.2		 1usqB-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.65A 1usqC-1de4A:
0.2		 1usqC-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.66A 1usqD-1de4A:
0.2		 1usqD-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.69A 1usqE-1de4A:
0.0		 1usqE-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.66A 1usqF-1de4A:
0.0		 1usqF-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.62A 2jkjA-1de4A:
0.2		 2jkjA-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.63A 2jkjB-1de4A:
0.2		 2jkjB-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.62A 2jkjC-1de4A:
0.0		 2jkjC-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.62A 2jkjE-1de4A:
undetectable		 2jkjE-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.65A 2jklA-1de4A:
0.2		 2jklA-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.64A 2jklB-1de4A:
0.0		 2jklB-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.65A 2jklC-1de4A:
undetectable		 2jklC-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.65A 2jklD-1de4A:
0.2		 2jklD-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.65A 2jklE-1de4A:
0.0		 2jklE-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.65A 2jklF-1de4A:
0.0		 2jklF-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		5 / 12 PHE A  12
LEU A 100
LEU A   8
ALA A  27
VAL A  37
 None
 1.25A 3cwkA-1de4A:
0.2		 3cwkA-1de4A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		4 / 7 PHE A  76
VAL A  98
LEU A 124
TRP A 147
 None
 0.91A 3hs6B-1de4A:
0.0		 3hs6B-1de4A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1de4 HEMOCHROMATOSIS
PROTEIN
(Homo
sapiens) 		3 / 3 THR A  82
MET A  84
HIS A  87
 None
 1.01A 5uunA-1de4A:
0.0		 5uunA-1de4A:
19.35