SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1del'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		5 / 10 ILE A 143
VAL A  99
GLY A  98
LEU A  90
TYR A 151
 None
 1.29A 1s1uA-1delA:
undetectable		 1s1uA-1delA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		5 / 12 ILE A  82
PHE A  61
ALA A  48
PHE A  47
LEU A  74
 None
 1.14A 2qb4A-1delA:
undetectable		 2qb4A-1delA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		5 / 11 ILE A  82
PHE A  61
ALA A  48
PHE A  47
LEU A  74
 None
 1.08A 2qjuA-1delA:
0.1		 2qjuA-1delA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		5 / 12 LEU A  40
ILE A  36
VAL A  79
HIS A 206
ARG A 133
 None
 1.28A 2qo4A-1delA:
0.0		 2qo4A-1delA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		5 / 12 LEU A  40
ILE A  36
VAL A  79
HIS A 206
ARG A 133
 None
 1.28A 2qo6A-1delA:
0.0		 2qo6A-1delA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		5 / 10 VAL A  79
ILE A 122
LEU A  90
LEU A 142
GLY A 139
 None
None
None
None
DGP  A 301 (-3.4A)
 1.10A 2xf3A-1delA:
0.0		 2xf3A-1delA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		4 / 6 LEU A 238
ILE A 234
MET A  22
VAL A 153
 None
 1.03A 2ygoA-1delA:
undetectable		 2ygoA-1delA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		3 / 3 SER A 202
GLY A 211
GLY A   8
 None
 0.54A 3bogA-1delA:
0.0
3bogC-1delA:
undetectable		 3bogA-1delA:
undetectable
3bogC-1delA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		4 / 8 ILE A 143
ASP A 148
ILE A  96
GLY A  92
 None
 0.76A 4acbC-1delA:
2.2		 4acbC-1delA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		4 / 8 LYS A  37
ARG A 132
ARG A  68
ASP A  15
 DGP  A 301 (-2.7A)
DGP  A 301 (-3.6A)
DGP  A 301 (-3.3A)
None
 1.37A 4kr4C-1delA:
0.0		 4kr4C-1delA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		4 / 7 LEU A   6
THR A 191
THR A 237
LEU A 238
 None
 0.80A 4z91F-1delA:
0.0
4z91G-1delA:
0.0
4z91H-1delA:
0.0
4z91I-1delA:
0.0
4z91J-1delA:
0.0		 4z91F-1delA:
20.62
4z91G-1delA:
20.62
4z91H-1delA:
20.62
4z91I-1delA:
20.62
4z91J-1delA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1del DEOXYNUCLEOSIDE
MONOPHOSPHATE KINASE
(Escherichia
virus
T4) 		4 / 9 ILE A  96
LYS A 117
ILE A 118
ILE A 122
 None
 0.75A 5vkqB-1delA:
0.0
5vkqC-1delA:
0.0		 5vkqB-1delA:
10.19
5vkqC-1delA:
10.19