SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1di4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1di4 LYSOZYME C
(Homo
sapiens) 		4 / 7 LEU A  25
LEU A   8
LEU A  15
GLY A  16
 None
 0.88A 1n13D-1di4A:
0.0
1n13E-1di4A:
undetectable		 1n13D-1di4A:
18.66
1n13E-1di4A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1di4 LYSOZYME C
(Homo
sapiens) 		4 / 8 LEU A   8
LEU A  15
GLY A  16
MET A  29
 None
 0.81A 1n13A-1di4A:
undetectable
1n13F-1di4A:
undetectable		 1n13A-1di4A:
17.65
1n13F-1di4A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1di4 LYSOZYME C
(Homo
sapiens) 		4 / 7 LEU A   8
LEU A  15
GLY A  16
MET A  29
 None
 0.80A 1n13G-1di4A:
undetectable
1n13J-1di4A:
0.0		 1n13G-1di4A:
17.65
1n13J-1di4A:
18.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N4F_A_ASRA141_0
(LYSOZYME C)		 1di4 LYSOZYME C
(Homo
sapiens) 		5 / 6 ASN A  66
ASP A  67
GLY A  68
THR A  70
PRO A  71
 None
 0.70A 1n4fA-1di4A:
25.1		 1n4fA-1di4A:
60.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1di4 LYSOZYME C
(Homo
sapiens) 		4 / 8 MET A  29
LEU A   8
LEU A  15
GLY A  16
 None
 0.85A 2qqcH-1di4A:
undetectable
2qqcK-1di4A:
undetectable		 2qqcH-1di4A:
19.40
2qqcK-1di4A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 1di4 LYSOZYME C
(Homo
sapiens) 		4 / 6 THR A  11
GLU A   7
MET A  29
ILE A  56
 None
 0.99A 2w98B-1di4A:
undetectable		 2w98B-1di4A:
18.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 1di4 LYSOZYME C
(Homo
sapiens) 		3 / 3 ASN A  46
ASP A  53
ASN A  60
 None
 0.68A 4agaA-1di4A:
25.2		 4agaA-1di4A:
60.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4II8_A_010A210_0
(LYSOZYME C)		 1di4 LYSOZYME C
(Homo
sapiens) 		6 / 7 GLU A  35
ASP A  53
GLN A  58
ASN A  60
TRP A  64
TRP A 109
 None
 0.62A 4ii8A-1di4A:
25.1		 4ii8A-1di4A:
60.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DL9_A_ACTA214_0
(LYSOZYME C)		 1di4 LYSOZYME C
(Homo
sapiens) 		5 / 5 GLU A  35
ASP A  53
TRP A 109
VAL A 110
ALA A 111
 None
 0.73A 5dl9A-1di4A:
25.1		 5dl9A-1di4A:
60.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1di4 LYSOZYME C
(Homo
sapiens) 		5 / 8 SER A  36
THR A  40
GLY A  55
ALA A  42
GLU A  35
 None
 1.21A 5vw9A-1di4A:
undetectable		 5vw9A-1di4A:
20.34