SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dix'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 1dix EXTRACELLULAR
RIBONUCLEASE LE
(Solanum
lycopersicum) 		5 / 12 THR A  29
GLY A  84
ASP A  67
ILE A  65
MET A  72
 None
 1.09A 2b25B-1dixA:
undetectable		 2b25B-1dixA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1dix EXTRACELLULAR
RIBONUCLEASE LE
(Solanum
lycopersicum) 		3 / 3 ASP A   5
ASP A 179
ASP A   3
 None
 0.76A 2igtA-1dixA:
undetectable		 2igtA-1dixA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1dix EXTRACELLULAR
RIBONUCLEASE LE
(Solanum
lycopersicum) 		3 / 3 ASP A   5
ASP A 179
ASP A   3
 None
 0.74A 2igtB-1dixA:
undetectable		 2igtB-1dixA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 1dix EXTRACELLULAR
RIBONUCLEASE LE
(Solanum
lycopersicum) 		4 / 6 LEU A 105
TRP A  76
MET A  72
LEU A  68
 None
 1.45A 2oz7A-1dixA:
undetectable		 2oz7A-1dixA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 1dix EXTRACELLULAR
RIBONUCLEASE LE
(Solanum
lycopersicum) 		3 / 3 SER A  87
HIS A 109
ASP A 117
 None
 0.76A 2wa2B-1dixA:
undetectable		 2wa2B-1dixA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 1dix EXTRACELLULAR
RIBONUCLEASE LE
(Solanum
lycopersicum) 		6 / 11 ALA A 110
GLY A 182
ASN A 107
SER A 103
VAL A 104
ALA A 101
 None
 1.37A 3dcmX-1dixA:
undetectable		 3dcmX-1dixA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1dix EXTRACELLULAR
RIBONUCLEASE LE
(Solanum
lycopersicum) 		5 / 12 ILE A 145
GLN A  11
PRO A  14
LEU A 171
PHE A  36
 None
 1.21A 5xxiA-1dixA:
0.0		 5xxiA-1dixA:
18.24