SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		3 / 3 PHE A 161
ARG A 205
ASN A 206
 None
 0.70A 1xzxX-1dj0A:
0.0		 1xzxX-1dj0A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		4 / 7 TYR A 120
THR A 137
VAL A  63
GLY A  62
 None
 0.90A 2a1mA-1dj0A:
undetectable		 2a1mA-1dj0A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		4 / 8 TYR A 120
THR A 137
VAL A  63
GLY A  62
 None
 0.82A 2a1mB-1dj0A:
undetectable		 2a1mB-1dj0A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		3 / 3 GLY A  20
TYR A  23
SER A  21
 None
 0.75A 2xatA-1dj0A:
0.0		 2xatA-1dj0A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		3 / 3 LEU A  91
TRP A  99
TYR A  18
 None
 0.95A 3aicA-1dj0A:
undetectable		 3aicA-1dj0A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		3 / 3 LEU A  91
TRP A  99
TYR A  18
 None
 1.00A 3aicB-1dj0A:
undetectable		 3aicB-1dj0A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		3 / 3 LEU A  91
TRP A  99
TYR A  18
 None
 0.99A 3aicE-1dj0A:
undetectable		 3aicE-1dj0A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		3 / 3 LEU A  91
TRP A  99
TYR A  18
 None
 0.92A 3aicF-1dj0A:
undetectable		 3aicF-1dj0A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		3 / 3 LEU A  91
TRP A  99
TYR A  18
 None
 0.98A 3aicG-1dj0A:
undetectable		 3aicG-1dj0A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		3 / 3 LEU A  91
TRP A  99
TYR A  18
 None
 1.00A 3aicH-1dj0A:
undetectable		 3aicH-1dj0A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		3 / 3 ALA A 249
VAL A  69
TRP A  99
 None
 0.86A 3l8lC-1dj0A:
undetectable
3l8lD-1dj0A:
undetectable		 3l8lC-1dj0A:
17.54
3l8lD-1dj0A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		4 / 6 LEU A  43
PHE A  72
ILE A  12
THR A  84
 None
 0.86A 3mdrA-1dj0A:
undetectable		 3mdrA-1dj0A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		5 / 10 ALA A 237
LEU A 227
ILE A 224
ALA A 152
VAL A 178
 None
 0.87A 3r9cA-1dj0A:
0.0		 3r9cA-1dj0A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		4 / 7 PRO A 261
ARG A  98
GLY A  15
VAL A  69
 None
 0.87A 4a3uB-1dj0A:
undetectable		 4a3uB-1dj0A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		5 / 12 LEU A 211
VAL A 214
ALA A 152
LEU A 228
LEU A 227
 None
 1.10A 4i1rA-1dj0A:
undetectable		 4i1rA-1dj0A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		4 / 6 GLU A  40
THR A  52
GLN A  36
TRP A  26
 None
 1.37A 4qztA-1dj0A:
undetectable		 4qztA-1dj0A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		4 / 4 GLU A  40
THR A  52
GLN A  36
TRP A  26
 None
 1.40A 4qztC-1dj0A:
0.0		 4qztC-1dj0A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		4 / 6 GLU A  40
THR A  52
GLN A  36
TRP A  26
 None
 1.38A 4qzuC-1dj0A:
undetectable		 4qzuC-1dj0A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		5 / 10 GLY A 215
ALA A 240
ILE A 122
LEU A 143
TYR A 120
 None
 1.03A 4xj7A-1dj0A:
undetectable
4xj7B-1dj0A:
undetectable		 4xj7A-1dj0A:
23.02
4xj7B-1dj0A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		5 / 12 ILE A 207
ILE A 194
VAL A 192
VAL A 190
LEU A 143
 None
 1.22A 4y0pA-1dj0A:
0.5		 4y0pA-1dj0A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		4 / 6 THR A  84
ASN A  88
ILE A  16
GLU A  17
 None
 1.08A 5uigA-1dj0A:
undetectable		 5uigA-1dj0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 1dj0 PSEUDOURIDINE
SYNTHASE I
(Escherichia
coli) 		4 / 4 PHE A 164
ASP A 160
LEU A 227
LYS A 231
 None
 1.45A 6awvA-1dj0A:
1.9		 6awvA-1dj0A:
17.69