SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dj2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 9 LEU A 347
ILE A 428
LEU A 361
VAL A 424
LEU A 333
 None
 1.17A 1e7aB-1dj2A:
0.0		 1e7aB-1dj2A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 8 LEU A  18
PHE A  45
VAL A  24
LEU A  37
ALA A  42
 None
 1.03A 1fiqC-1dj2A:
0.0		 1fiqC-1dj2A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 9 LEU A  18
PHE A  45
VAL A  24
LEU A  37
ALA A  42
 None
 1.04A 1fo4A-1dj2A:
0.0		 1fo4A-1dj2A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 8 GLY A 240
GLY A  77
LEU A 237
SER A  76
ARG A  50
 None
 1.30A 1jhvA-1dj2A:
undetectable		 1jhvA-1dj2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 8 ILE A 431
LEU A 350
ILE A 433
VAL A 403
ILE A 441
 None
 0.94A 1linA-1dj2A:
undetectable		 1linA-1dj2A:
13.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MF1_A_ACTA458_0
(ADENYLOSUCCINATE
SYNTHETASE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 4 GLY A  33
LYS A  34
GLY A  35
HIS A  59
 GDP  A 500 (-2.7A)
GDP  A 500 (-2.5A)
GDP  A 500 (-4.0A)
GDP  A 500 (-3.2A)
 0.45A 1mf1A-1dj2A:
58.3		 1mf1A-1dj2A:
48.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 4 ILE A  40
LEU A  41
VAL A  24
ALA A 263
 None
 0.89A 1mz9A-1dj2A:
undetectable		 1mz9A-1dj2A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 5 ILE A  40
LEU A  41
VAL A  24
ALA A 263
 None
 0.83A 1mz9C-1dj2A:
0.0		 1mz9C-1dj2A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 4 SER A 158
VAL A  92
PHE A 128
VAL A 132
 None
 1.49A 1o86A-1dj2A:
0.0		 1o86A-1dj2A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 11 LEU A 270
GLY A 240
ARG A  50
HIS A  59
VAL A  91
 None
None
None
GDP  A 500 (-3.2A)
None
 1.31A 1tmxA-1dj2A:
undetectable		 1tmxA-1dj2A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 269
GLY A  90
GLY A  53
VAL A 223
ILE A 272
 None
 0.90A 2b25A-1dj2A:
2.3		 2b25A-1dj2A:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 11 ALA A 311
GLN A 360
LEU A 308
ASN A 300
LEU A 356
 None
 1.06A 2ceoA-1dj2A:
undetectable		 2ceoA-1dj2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 6 PHE A  45
VAL A  24
LEU A  37
ALA A  42
 None
 1.03A 2e1qA-1dj2A:
1.2		 2e1qA-1dj2A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 6 PHE A  45
VAL A  24
LEU A  37
ALA A  42
 None
 1.01A 2e1qC-1dj2A:
0.0		 2e1qC-1dj2A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 ILE A  87
GLY A 269
GLY A  54
ALA A 122
HIS A 123
 None
 0.86A 2fk8A-1dj2A:
undetectable		 2fk8A-1dj2A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 264
GLY A 271
GLY A 269
ILE A 230
VAL A 276
 None
 0.75A 2oxtB-1dj2A:
undetectable		 2oxtB-1dj2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 10 ALA A 311
GLN A 360
LEU A 308
ASN A 300
LEU A 356
 None
 0.97A 2riwA-1dj2A:
undetectable
2riwB-1dj2A:
0.0		 2riwA-1dj2A:
22.25
2riwB-1dj2A:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 GLY A  97
TYR A 208
LEU A 170
VAL A 167
SER A 119
 None
 1.50A 2vqyA-1dj2A:
0.0		 2vqyA-1dj2A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 10 ALA A 311
GLN A 360
LEU A 308
ASN A 300
LEU A 356
 None
 1.04A 2xn6A-1dj2A:
undetectable
2xn6B-1dj2A:
0.0		 2xn6A-1dj2A:
21.79
2xn6B-1dj2A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 10 ALA A 311
GLN A 360
LEU A 308
ASN A 300
LEU A 356
 None
 0.98A 2xn7A-1dj2A:
0.0
2xn7B-1dj2A:
0.0		 2xn7A-1dj2A:
21.79
2xn7B-1dj2A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 9 THR A 318
VAL A 291
ARG A 324
ILE A 145
GLY A  58
 None
 1.28A 3cv9A-1dj2A:
0.0		 3cv9A-1dj2A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 9 VAL A  91
LEU A  98
SER A 119
ILE A 116
GLY A 240
 None
 1.18A 3cv9A-1dj2A:
0.0		 3cv9A-1dj2A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		3 / 3 TYR A 287
TYR A 416
ILE A 359
 None
 0.66A 3eteA-1dj2A:
0.0
3eteB-1dj2A:
0.9		 3eteA-1dj2A:
21.70
3eteB-1dj2A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 241
GLY A  88
GLY A  90
GLY A  53
ASP A 221
 None
 1.04A 3gczA-1dj2A:
undetectable		 3gczA-1dj2A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 SER A 259
GLY A  88
GLY A  90
GLY A  53
ASP A 221
 None
 1.05A 3gczA-1dj2A:
undetectable		 3gczA-1dj2A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 GLU A 101
LEU A 105
ASP A 103
LEU A  71
CYH A 112
 None
 1.11A 3ko0M-1dj2A:
undetectable
3ko0N-1dj2A:
undetectable
3ko0O-1dj2A:
undetectable
3ko0P-1dj2A:
undetectable		 3ko0M-1dj2A:
11.74
3ko0N-1dj2A:
11.74
3ko0O-1dj2A:
11.74
3ko0P-1dj2A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 GLU A 101
LEU A 105
LEU A  71
ILE A  78
CYH A 112
 None
 1.11A 3ko0M-1dj2A:
undetectable
3ko0N-1dj2A:
undetectable
3ko0O-1dj2A:
undetectable
3ko0P-1dj2A:
undetectable		 3ko0M-1dj2A:
11.74
3ko0N-1dj2A:
11.74
3ko0O-1dj2A:
11.74
3ko0P-1dj2A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 HIS A 429
TYR A 430
LEU A  37
GLY A 278
LEU A 237
 None
 1.08A 3ln1D-1dj2A:
0.0		 3ln1D-1dj2A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 HIS A 429
TYR A 430
LEU A  37
GLY A 278
LEU A 237
 None
 1.02A 3n8xB-1dj2A:
0.0		 3n8xB-1dj2A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 8 ALA A 122
VAL A 167
ASP A 120
LEU A 117
 None
 0.83A 3roxA-1dj2A:
2.5		 3roxA-1dj2A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 9 LEU A  18
PHE A  45
VAL A  24
LEU A  37
ALA A  42
 None
 1.05A 3unaA-1dj2A:
0.0		 3unaA-1dj2A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 9 LEU A  18
PHE A  45
VAL A  24
LEU A  37
ALA A  42
 None
 1.04A 3unaB-1dj2A:
1.1		 3unaB-1dj2A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 9 LEU A  18
PHE A  45
VAL A  24
LEU A  37
ALA A  42
 None
 1.03A 3uncA-1dj2A:
0.0		 3uncA-1dj2A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 9 LEU A  18
PHE A  45
VAL A  24
LEU A  37
ALA A  42
 None
 1.04A 3uncB-1dj2A:
0.0		 3uncB-1dj2A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 SER A  22
ASP A  46
ILE A  47
ALA A  49
VAL A  86
 None
 1.07A 4dx5B-1dj2A:
undetectable		 4dx5B-1dj2A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 ASP A 127
TYR A 211
LEU A 124
LEU A 170
HIS A  94
 None
 1.16A 4j03A-1dj2A:
undetectable		 4j03A-1dj2A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 102
TYR A 208
PHE A 126
LEU A 180
LEU A 215
 None
 1.27A 4j03A-1dj2A:
undetectable		 4j03A-1dj2A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 SER A  22
ASP A  46
ILE A  47
ALA A  49
VAL A  86
 None
 1.06A 4u8vB-1dj2A:
0.0		 4u8vB-1dj2A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 SER A  22
ASP A  46
ILE A  47
ALA A  49
VAL A  86
 None
 1.05A 4u8yB-1dj2A:
0.0		 4u8yB-1dj2A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 SER A  22
ASP A  46
ILE A  47
ALA A  49
VAL A  86
 None
 1.09A 4u95B-1dj2A:
undetectable		 4u95B-1dj2A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 9 ALA A 311
GLN A 360
LEU A 308
ASN A 300
LEU A 356
 None
 1.03A 4x30A-1dj2A:
undetectable		 4x30A-1dj2A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		3 / 3 THR A 222
HIS A  94
LEU A  73
 None
 0.88A 5axdC-1dj2A:
1.3		 5axdC-1dj2A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 GLY A 241
GLY A  88
GLY A  90
GLY A  53
ASP A 221
 None
 1.01A 5ehiC-1dj2A:
undetectable		 5ehiC-1dj2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 12 SER A 259
GLY A  88
GLY A  90
GLY A  53
ASP A 221
 None
 0.96A 5ekxA-1dj2A:
undetectable		 5ekxA-1dj2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 8 SER A 119
GLY A  90
ALA A 122
GLY A 269
 None
 0.74A 5vw9A-1dj2A:
undetectable		 5vw9A-1dj2A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 5 VAL A  86
THR A  84
LEU A 270
VAL A 276
 None
 0.94A 6bqgA-1dj2A:
0.0		 6bqgA-1dj2A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 8 TYR A 416
THR A 348
TYR A 287
TRP A 396
 None
GDP  A 500 ( 4.9A)
None
None
 1.38A 6cnjD-1dj2A:
undetectable
6cnjE-1dj2A:
undetectable		 6cnjD-1dj2A:
11.42
6cnjE-1dj2A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 125
LEU A 183
ASP A 186
ILE A 152
SER A 157
 None
 1.48A 6dlzB-1dj2A:
undetectable
6dlzC-1dj2A:
undetectable		 6dlzB-1dj2A:
14.29
6dlzC-1dj2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 125
LEU A 183
ASP A 186
ILE A 152
SER A 157
 None
 1.48A 6dm1B-1dj2A:
undetectable
6dm1C-1dj2A:
undetectable		 6dm1B-1dj2A:
14.29
6dm1C-1dj2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 10 LEU A 125
LEU A 183
ASP A 186
ILE A 152
SER A 157
 None
 1.48A 6dm2B-1dj2A:
undetectable
6dm2C-1dj2A:
undetectable		 6dm2B-1dj2A:
14.29
6dm2C-1dj2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 10 ILE A 152
SER A 157
LEU A 125
LEU A 183
ASP A 186
 None
 1.49A 6dm2A-1dj2A:
undetectable
6dm2D-1dj2A:
undetectable		 6dm2A-1dj2A:
14.29
6dm2D-1dj2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		4 / 8 ASP A 181
TYR A 196
GLY A 193
VAL A 132
 None
 1.05A 6giqL-1dj2A:
0.0
6giqP-1dj2A:
0.0
6giqT-1dj2A:
0.0		 6giqL-1dj2A:
23.75
6giqP-1dj2A:
21.41
6giqT-1dj2A:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 1dj2 ADENYLOSUCCINATE
SYNTHETASE
(Arabidopsis
thaliana) 		5 / 11 ILE A  40
LEU A  41
THR A  83
ASN A  80
LEU A  79
 None
 1.37A 6hupA-1dj2A:
0.0
6hupB-1dj2A:
0.0		 6hupA-1dj2A:
11.75
6hupB-1dj2A:
11.08