SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1djp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 12 GLY A1168
GLY A1156
VAL A1159
GLN A1166
ASN A1284
 None
 1.23A 1n2xA-1djpA:
undetectable		 1n2xA-1djpA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 12 THR A1102
GLY A1099
VAL A1122
ALA A1037
ALA A1036
 None
DO2  A4000 (-3.5A)
None
None
DO2  A4000 ( 4.0A)
 1.06A 1nw5A-1djpA:
undetectable		 1nw5A-1djpA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 12 LEU A1112
PHE A1109
ILE A1218
LEU A1221
PRO A1222
 None
 1.25A 1re7B-1djpA:
undetectable		 1re7B-1djpA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 11 SER A1220
VAL A1113
LEU A1221
ILE A1315
MET A1318
 None
 1.24A 1uduA-1djpA:
undetectable		 1uduA-1djpA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		4 / 8 SER A1184
ASP A1307
LEU A1316
LEU A1112
 None
 1.01A 2bfpD-1djpA:
1.9		 2bfpD-1djpA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 12 ALA A1240
LEU A1241
ALA A1242
THR A1275
GLN A1295
 None
 1.17A 2jjpA-1djpA:
0.0		 2jjpA-1djpA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		4 / 7 VAL A1233
SER A1229
HIS A1251
LEU A1267
 None
 1.22A 3arrA-1djpA:
1.9		 3arrA-1djpA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		4 / 4 LEU A1330
ALA A1248
VAL A1224
PRO A1222
 None
 1.01A 3gv1B-1djpA:
undetectable		 3gv1B-1djpA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 10 LEU A1110
ILE A1014
VAL A1095
GLY A1124
VAL A1157
 None
 1.14A 3ogpB-1djpA:
undetectable		 3ogpB-1djpA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 12 GLY A1093
SER A1148
ASN A1149
ASP A1117
ASN A1011
 None
 1.15A 3q87B-1djpA:
undetectable		 3q87B-1djpA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		4 / 5 VAL A1013
VAL A1012
ARG A1058
LYS A1118
 None
 1.30A 3rv5A-1djpA:
0.0
3rv5B-1djpA:
0.0		 3rv5A-1djpA:
15.31
3rv5B-1djpA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		4 / 7 THR A1097
GLY A1124
GLY A1129
THR A1130
 None
 0.76A 3tajA-1djpA:
2.2		 3tajA-1djpA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		4 / 8 LEU A1075
LEU A1078
GLY A1079
VAL A1157
 None
 0.79A 4c9nA-1djpA:
0.0		 4c9nA-1djpA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 12 LEU A1110
LEU A1075
ILE A1094
THR A1102
VAL A1062
 None
 1.23A 4f4dB-1djpA:
4.4		 4f4dB-1djpA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		4 / 7 GLU A1104
THR A1020
ASN A1176
SER A1067
 None
DO2  A4000 (-2.1A)
None
DO2  A4000 (-2.4A)
 1.13A 4pfjA-1djpA:
2.9		 4pfjA-1djpA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 12 VAL A1192
ASP A1163
ALA A1145
GLY A1136
LEU A1140
 None
 1.22A 5m54E-1djpA:
2.6		 5m54E-1djpA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		5 / 12 LEU A1044
GLY A1136
GLY A1124
VAL A1123
THR A1097
 None
 1.00A 5o4yD-1djpA:
undetectable
5o4yE-1djpA:
0.0		 5o4yD-1djpA:
6.50
5o4yE-1djpA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 1djp GLUTAMINASE-ASPARAGI
NASE
(Pseudomonas
sp.
7A) 		4 / 5 LEU A1078
VAL A1062
GLU A1060
LEU A1015
 None
 1.08A 5xooB-1djpA:
undetectable		 5xooB-1djpA:
12.90