SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A 242
LEU A  94
GLY A  95
GLN A  98
THR A 234
 None
None
PLP  A 400 (-3.2A)
None
None
 1.43A 1p93A-1djuA:
undetectable		 1p93A-1djuA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 7 THR A 161
LEU A 194
VAL A 138
ILE A 116
 None
 0.81A 1t87B-1djuA:
0.0		 1t87B-1djuA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		5 / 9 LEU A 310
LEU A 383
VAL A 345
ALA A 346
PHE A 335
 None
 1.09A 1tbfA-1djuA:
undetectable		 1tbfA-1djuA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 6 MET A  91
VAL A  92
LEU A  93
MET A 102
 None
 1.19A 1x8vA-1djuA:
0.0		 1x8vA-1djuA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 7 ARG A 282
ALA A 273
ASP A 280
TYR A  47
 None
 1.26A 2e5dA-1djuA:
undetectable
2e5dB-1djuA:
0.0		 2e5dA-1djuA:
22.50
2e5dB-1djuA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 7 ASP A 280
TYR A  47
ARG A 282
ALA A 273
 None
 1.27A 2e5dA-1djuA:
undetectable
2e5dB-1djuA:
undetectable		 2e5dA-1djuA:
22.50
2e5dB-1djuA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 5 GLY A  95
GLY A 243
PHE A 121
PHE A 100
 PLP  A 400 (-3.2A)
PLP  A 400 ( 4.9A)
PLP  A 400 (-3.7A)
None
 1.03A 2qr2A-1djuA:
2.3
2qr2B-1djuA:
2.3		 2qr2A-1djuA:
19.18
2qr2B-1djuA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		3 / 3 GLY A  95
GLY A 230
GLY A 243
 PLP  A 400 (-3.2A)
None
PLP  A 400 ( 4.9A)
 0.42A 3bogC-1djuA:
0.0		 3bogC-1djuA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		3 / 3 GLY A  95
GLY A 230
GLY A 243
 PLP  A 400 (-3.2A)
None
PLP  A 400 ( 4.9A)
 0.34A 3bogD-1djuA:
0.0		 3bogD-1djuA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		5 / 11 PHE A 231
ILE A  90
ALA A 275
GLU A  70
PRO A 266
 None
 1.06A 3tmzA-1djuA:
0.0		 3tmzA-1djuA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 6 ILE A 215
THR A 225
VAL A 176
SER A 217
 None
 1.12A 4iaqA-1djuA:
undetectable		 4iaqA-1djuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 7 ALA A 352
SER A 351
VAL A 361
ARG A 362
 None
 1.16A 4ijiH-1djuA:
undetectable		 4ijiH-1djuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 6 LEU A 305
ASN A 306
MET A 339
LEU A 383
 None
 1.11A 4okbA-1djuA:
0.0		 4okbA-1djuA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 6 LEU A 305
ASN A 306
MET A 339
LEU A 383
 None
 1.13A 4okxA-1djuA:
0.0		 4okxA-1djuA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		5 / 12 PHE A 353
VAL A 361
GLY A 350
SER A 336
SER A  30
 None
 1.26A 4ot2A-1djuA:
undetectable		 4ot2A-1djuA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 8 GLU A  35
ASP A  37
SER A 364
ARG A 297
 None
 1.16A 4uhxA-1djuA:
undetectable		 4uhxA-1djuA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 8 GLU A  35
ASP A  37
SER A 364
ARG A 297
 None
 1.16A 4uhxA-1djuA:
undetectable		 4uhxA-1djuA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 7 ASN A 171
PRO A 172
PHE A 322
TYR A 365
 PLP  A 400 (-3.9A)
None
None
None
 1.50A 5amhA-1djuA:
undetectable		 5amhA-1djuA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		3 / 3 SER A 332
SER A 336
PHE A 322
 None
 0.87A 5mugA-1djuA:
undetectable		 5mugA-1djuA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		4 / 7 ARG A 326
ARG A 324
THR A 312
PRO A 323
 None
 1.28A 6a4iB-1djuA:
undetectable		 6a4iB-1djuA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 1dju AROMATIC
AMINOTRANSFERASE
(Pyrococcus
horikoshii) 		3 / 3 LEU A 330
SER A 332
PHE A 335
 None
 0.64A 6fgcA-1djuA:
0.8		 6fgcA-1djuA:
23.56