SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dk5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 8 ARG A 239
LEU A 225
VAL A 246
GLY A 244
 SO4  A 811 (-4.3A)
SO4  A 811 (-4.7A)
None
None
 1.03A 1hrkB-1dk5A:
undetectable		 1hrkB-1dk5A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_0
(PROTEIN (METHIONINE
REPRESSOR))		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 9 ARG A  58
ARG A  54
GLU A 279
ALA A 275
PRO A  92
 None
 1.20A 1mj2A-1dk5A:
undetectable		 1mj2A-1dk5A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_0
(PROTEIN (METHIONINE
REPRESSOR))		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 9 ARG A  58
ARG A  54
GLU A 279
ALA A 275
PRO A  92
 None
 1.19A 1mj2C-1dk5A:
undetectable		 1mj2C-1dk5A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_0
(METHIONINE REPRESSOR)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 9 ARG A  58
ARG A  54
GLU A 279
ALA A 275
PRO A  92
 None
 1.19A 1mjoA-1dk5A:
undetectable		 1mjoA-1dk5A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_1
(METHIONINE REPRESSOR)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 9 ARG A  58
ARG A  54
GLU A 279
ALA A 275
PRO A  92
 None
 1.21A 1mjoB-1dk5A:
undetectable		 1mjoB-1dk5A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_0
(METHIONINE REPRESSOR)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 9 ARG A  58
ARG A  54
GLU A 279
ALA A 275
PRO A  92
 None
 1.17A 1mjoC-1dk5A:
undetectable		 1mjoC-1dk5A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 12 LEU A 237
VAL A 161
ALA A 118
LEU A 117
LEU A 157
 None
 1.25A 2c12C-1dk5A:
0.0		 2c12C-1dk5A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 11 LEU A 237
VAL A 161
ALA A 118
LEU A 117
LEU A 157
 None
 1.24A 2c12F-1dk5A:
0.0		 2c12F-1dk5A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 7 ARG A  95
SER A  93
ARG A  54
GLU A 125
 None
 1.13A 2c8aA-1dk5A:
undetectable		 2c8aA-1dk5A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 6 ARG A  95
SER A  93
ARG A  54
GLU A 125
 None
 1.19A 2c8aC-1dk5A:
undetectable		 2c8aC-1dk5A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 6 LEU A 183
TYR A 216
ILE A 242
ILE A 187
 None
 1.00A 2q8hA-1dk5A:
0.0		 2q8hA-1dk5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 5 PRO A 248
ILE A 285
ARG A 277
ASP A 281
 SO4  A 806 (-3.8A)
None
None
None
 1.25A 2rhmB-1dk5A:
undetectable		 2rhmB-1dk5A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 5 PRO A 248
ILE A 285
ARG A 277
ASP A 281
 SO4  A 806 (-3.8A)
None
None
None
 1.39A 2rhmD-1dk5A:
undetectable		 2rhmD-1dk5A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 8 LEU A  28
ILE A  42
LEU A  46
LEU A  69
 None
 0.79A 2xfhA-1dk5A:
0.0		 2xfhA-1dk5A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 4 LEU A 317
ARG A 257
LEU A 256
ALA A 300
 None
 1.07A 3b9mA-1dk5A:
0.6		 3b9mA-1dk5A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 12 LEU A 238
ALA A 240
GLY A 231
ILE A 242
LEU A 225
 None
None
None
None
SO4  A 811 (-4.7A)
 1.23A 3gyqA-1dk5A:
undetectable
3gyqB-1dk5A:
undetectable		 3gyqA-1dk5A:
24.50
3gyqB-1dk5A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		3 / 3 ARG A  95
LEU A  99
THR A 120
 None
SO4  A 801 ( 4.9A)
None
 0.85A 3oxcA-1dk5A:
undetectable		 3oxcA-1dk5A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 12 LEU A 297
TYR A 289
ILE A 301
ASP A 258
ALA A 259
 None
 1.24A 3uj7A-1dk5A:
0.0		 3uj7A-1dk5A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 7 ASP A 189
SER A 188
TYR A 216
HIS A 184
 None
 1.34A 4arcA-1dk5A:
0.0		 4arcA-1dk5A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 11 ILE A 242
ALA A 202
LEU A 201
VAL A 197
LEU A 238
 None
 1.07A 4g1bB-1dk5A:
undetectable		 4g1bB-1dk5A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 12 ILE A 242
THR A 241
ALA A 202
LEU A 238
LEU A 156
 None
 1.12A 4pbhA-1dk5A:
0.0		 4pbhA-1dk5A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 6 LEU A 157
THR A 120
ALA A 118
SER A 162
 None
 1.05A 4pwjA-1dk5A:
undetectable		 4pwjA-1dk5A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		3 / 3 LYS A 190
ILE A 187
ILE A 224
 None
 0.62A 4y0qA-1dk5A:
undetectable		 4y0qA-1dk5A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 7 LEU A 256
THR A 265
THR A 305
LEU A 313
 None
 0.95A 4z91F-1dk5A:
0.2
4z91G-1dk5A:
0.2
4z91H-1dk5A:
0.3
4z91I-1dk5A:
0.0
4z91J-1dk5A:
0.3		 4z91F-1dk5A:
23.63
4z91G-1dk5A:
23.63
4z91H-1dk5A:
23.63
4z91I-1dk5A:
23.63
4z91J-1dk5A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 11 MET A 312
LEU A 316
LEU A  12
LEU A  86
LEU A  70
 None
 0.98A 4zowA-1dk5A:
0.2		 4zowA-1dk5A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 5 ILE A 285
LEU A 313
HIS A 269
VAL A 255
 None
None
SO4  A 809 (-3.9A)
None
 1.03A 5jmnB-1dk5A:
undetectable		 5jmnB-1dk5A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		4 / 5 VAL A  87
THR A 276
ASP A  96
LEU A  99
 None
None
None
SO4  A 801 ( 4.9A)
 1.21A 5m0iB-1dk5A:
undetectable		 5m0iB-1dk5A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		5 / 10 ALA A 236
VAL A 235
LYS A 190
ILE A 187
ILE A 224
 None
 1.19A 5nukA-1dk5A:
undetectable		 5nukA-1dk5A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		3 / 3 ARG A  95
ARG A  58
ARG A 136
 None
None
SO4  A 802 (-2.8A)
 1.00A 5vcgA-1dk5A:
0.0		 5vcgA-1dk5A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_1
(ALPHA-AMYLASE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		3 / 3 TYR A 309
ALA A 315
LEU A 316
 None
 0.56A 6ag0C-1dk5A:
undetectable		 6ag0C-1dk5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 1dk5 ANNEXIN 24(CA32)
(Capsicum
annuum) 		3 / 3 PHE A 252
ARG A 272
ALA A 240
 None
SO4  A 809 (-4.5A)
None
 0.93A 6ecfB-1dk5A:
undetectable		 6ecfB-1dk5A:
26.15