SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dkd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1dkd GROEL
(Escherichia
coli) 		4 / 4 SER A 217
VAL A 323
PHE A 219
VAL A 240
 None
 1.43A 1o86A-1dkdA:
undetectable		 1o86A-1dkdA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 1dkd GROEL
(Escherichia
coli) 		5 / 9 LEU A 222
VAL A 276
ILE A 325
PRO A 279
ILE A 250
 None
 1.01A 1ohrB-1dkdA:
undetectable		 1ohrB-1dkdA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 1dkd GROEL
(Escherichia
coli) 		5 / 12 LEU A 247
LEU A 248
VAL A 254
LEU A 262
THR A 266
 None
 1.25A 2q7kA-1dkdA:
undetectable		 2q7kA-1dkdA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1dkd GROEL
(Escherichia
coli) 		5 / 9 LEU A 221
LEU A 237
ALA A 275
LEU A 262
ALA A 258
 None
 1.18A 2vcvD-1dkdA:
0.5		 2vcvD-1dkdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1dkd GROEL
(Escherichia
coli) 		5 / 9 LEU A 221
LEU A 237
ALA A 275
LEU A 262
ALA A 258
 None
 1.15A 2vcvE-1dkdA:
undetectable		 2vcvE-1dkdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1dkd GROEL
(Escherichia
coli) 		4 / 7 LEU A 221
ALA A 275
LEU A 262
ALA A 258
 None
 1.00A 2vcvG-1dkdA:
0.0		 2vcvG-1dkdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1dkd GROEL
(Escherichia
coli) 		5 / 9 LEU A 221
LEU A 237
ALA A 275
LEU A 262
ALA A 258
 None
 1.16A 2vcvH-1dkdA:
undetectable		 2vcvH-1dkdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1dkd GROEL
(Escherichia
coli) 		5 / 9 LEU A 221
LEU A 237
ALA A 275
LEU A 262
ALA A 258
 None
 1.12A 2vcvI-1dkdA:
0.6		 2vcvI-1dkdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 1dkd GROEL
(Escherichia
coli) 		5 / 9 LEU A 222
VAL A 276
ILE A 325
PRO A 279
ILE A 250
 None
 1.03A 3ekqB-1dkdA:
undetectable		 3ekqB-1dkdA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 1dkd GROEL
(Escherichia
coli) 		5 / 12 ALA A 251
ILE A 301
VAL A 300
ILE A 292
ILE A 249
 None
 0.95A 3ekwB-1dkdA:
undetectable		 3ekwB-1dkdA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1dkd GROEL
(Escherichia
coli) 		5 / 12 LEU A 309
LEU A 237
ILE A 230
ALA A 258
ALA A 275
 None
 0.90A 3mdvB-1dkdA:
undetectable		 3mdvB-1dkdA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 1dkd GROEL
(Escherichia
coli) 		5 / 9 PHE A 195
LEU A 248
VAL A 323
THR A 296
ILE A 332
 None
 1.17A 3tbgD-1dkdA:
undetectable		 3tbgD-1dkdA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1dkd GROEL
(Escherichia
coli) 		5 / 12 ILE A 292
ALA A 278
LEU A 222
ALA A 223
VAL A 323
 None
 1.06A 4k6iA-1dkdA:
undetectable		 4k6iA-1dkdA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 1dkd GROEL
(Escherichia
coli) 		5 / 9 LEU A 222
VAL A 276
ILE A 325
PRO A 279
ILE A 250
 None
 1.10A 5kqxB-1dkdA:
undetectable		 5kqxB-1dkdA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 1dkd GROEL
(Escherichia
coli) 		4 / 5 LEU A 222
LEU A 221
MET A 307
GLN A 290
 None
 1.35A 5uc3A-1dkdA:
0.0		 5uc3A-1dkdA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1dkd GROEL
(Escherichia
coli) 		5 / 7 GLY A 298
LEU A 222
LEU A 215
ILE A 292
LEU A 295
 None
 1.36A 5vkqA-1dkdA:
0.0
5vkqB-1dkdA:
0.0		 5vkqA-1dkdA:
6.98
5vkqB-1dkdA:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 1dkd GROEL
(Escherichia
coli) 		5 / 12 ALA A 258
ALA A 251
ILE A 249
LYS A 277
ALA A 275
 None
 0.91A 5xiwD-1dkdA:
undetectable		 5xiwD-1dkdA:
15.97