SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dl3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		4 / 8 ASN A 164
LEU A 160
GLY A 158
TRP A 141
 None
None
SO4  A 300 ( 4.1A)
None
 0.87A 1rukH-1dl3A:
undetectable
1rukL-1dl3A:
undetectable		 1rukH-1dl3A:
19.83
1rukL-1dl3A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		4 / 8 LEU A 124
VAL A  57
TYR A  25
GLY A  27
 None
 0.93A 1s1xA-1dl3A:
undetectable		 1s1xA-1dl3A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		4 / 8 PHE A  17
SER A  18
ILE A 199
LYS A 200
 None
 0.84A 1sbrA-1dl3A:
undetectable		 1sbrA-1dl3A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		5 / 12 GLY A  22
ALA A  23
VAL A   2
VAL A 179
ILE A   6
 None
None
None
SO4  A 300 (-4.0A)
None
 0.99A 2f8gA-1dl3A:
undetectable		 2f8gA-1dl3A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		4 / 6 ILE A 144
ARG A 148
LEU A 145
LEU A 156
 None
 1.06A 2rlfA-1dl3A:
0.0
2rlfD-1dl3A:
0.0		 2rlfA-1dl3A:
13.93
2rlfD-1dl3A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		5 / 12 GLY A  22
ALA A  23
VAL A   2
VAL A 179
ILE A   6
 None
None
None
SO4  A 300 (-4.0A)
None
 0.86A 3cyxA-1dl3A:
undetectable		 3cyxA-1dl3A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		4 / 7 ILE A  46
GLY A   8
TYR A  37
LEU A  77
 None
 0.84A 3elzA-1dl3A:
0.0		 3elzA-1dl3A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		3 / 3 VAL A  75
SER A  47
LEU A  77
 None
 0.74A 3n8xA-1dl3A:
0.0		 3n8xA-1dl3A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		5 / 12 GLY A  22
ALA A  23
VAL A   2
VAL A 179
ILE A   6
 None
None
None
SO4  A 300 (-4.0A)
None
 0.95A 3oxxC-1dl3A:
undetectable		 3oxxC-1dl3A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		5 / 8 VAL A   4
ASP A  24
SER A  18
GLY A  22
ALA A 202
 None
 1.17A 4m48A-1dl3A:
0.0		 4m48A-1dl3A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		3 / 3 LYS A 190
ILE A 195
ILE A 199
 None
 0.68A 4y0qA-1dl3A:
0.0		 4y0qA-1dl3A:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)
(Thermotoga
maritima) 		4 / 9 PHE A 121
LEU A 154
VAL A 177
ASP A 178
 None
 0.84A 6c2mD-1dl3A:
0.0		 6c2mD-1dl3A:
16.67