SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dlj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		4 / 6 PRO A 350
ASP A 383
ASN A 384
TYR A 348
 None
 1.03A 1hpkA-1dljA:
0.0		 1hpkA-1dljA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		5 / 12 SER A 232
LEU A 221
HIS A 248
PHE A 218
ILE A 245
 None
 1.49A 1uobA-1dljA:
undetectable		 1uobA-1dljA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		5 / 12 ALA A 216
PRO A 262
GLY A 257
GLY A 255
TYR A  85
 None
None
UGA  A 404 (-3.2A)
None
None
 1.09A 2igtB-1dljA:
4.9		 2igtB-1dljA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		4 / 8 PHE A 254
ILE A 331
ALA A 295
VAL A 312
 None
 0.91A 3me6B-1dljA:
0.0		 3me6B-1dljA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		4 / 8 PHE A  92
ASN A 271
GLU A 126
LEU A 205
 None
 1.11A 3rqwC-1dljA:
0.0
3rqwD-1dljA:
0.0		 3rqwC-1dljA:
20.95
3rqwD-1dljA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		4 / 8 GLU A 126
LEU A 205
PHE A  92
ASN A 271
 None
 1.13A 3rqwF-1dljA:
0.0
3rqwJ-1dljA:
0.0		 3rqwF-1dljA:
20.95
3rqwJ-1dljA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		5 / 12 GLY A 255
GLY A 257
ILE A 331
ILE A 294
SER A 253
 None
UGA  A 404 (-3.2A)
None
None
UGA  A 404 (-2.7A)
 1.12A 4iv0B-1dljA:
5.4		 4iv0B-1dljA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		5 / 12 ARG A 157
PRO A 155
ALA A 184
ILE A 194
GLY A 196
 None
 1.07A 4l9qA-1dljA:
undetectable		 4l9qA-1dljA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		5 / 12 GLY A 255
GLY A 257
ILE A 331
ILE A 294
SER A 253
 None
UGA  A 404 (-3.2A)
None
None
UGA  A 404 (-2.7A)
 1.12A 4mwzA-1dljA:
5.4		 4mwzA-1dljA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		3 / 3 VAL A 389
LEU A 386
VAL A 393
 None
 0.55A 4wq4A-1dljA:
0.0		 4wq4A-1dljA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		4 / 7 ILE A 346
ILE A 343
ILE A 376
LEU A 338
 None
 0.82A 5fukA-1dljA:
0.0
5fukB-1dljA:
0.0		 5fukA-1dljA:
20.25
5fukB-1dljA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		3 / 3 VAL A  28
LYS A   2
MET A   1
 None
 1.07A 5nknA-1dljA:
0.0		 5nknA-1dljA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1dlj UDP-GLUCOSE
DEHYDROGENASE
(Streptococcus
pyogenes) 		3 / 3 LEU A 213
ILE A 283
TYR A 272
 None
 0.47A 5uunB-1dljA:
undetectable		 5uunB-1dljA:
21.14