SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dlk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		6 / 8 HIS B  57
SER B 190
SER B 195
VAL B 213
GLY B 216
GLY B 226
 None
 0.77A 1aq7A-1dlkB:
36.2		 1aq7A-1dlkB:
43.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		5 / 9 SER B 195
VAL B 213
TRP B 215
GLY B 216
GLY B 226
 None
 0.26A 1bcuH-1dlkB:
35.3		 1bcuH-1dlkB:
35.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		6 / 12 HIS B  57
SER B 195
VAL B 213
TRP B 215
GLY B 216
GLY B 226
 None
 0.60A 1etrH-1dlkB:
34.6		 1etrH-1dlkB:
36.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 8 SER B 190
SER B 195
VAL B 213
GLY B 226
 None
 0.63A 1f5lA-1dlkB:
35.1		 1f5lA-1dlkB:
33.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 8 SER B 195
VAL B 213
GLY B 216
GLY B 226
 None
 0.23A 1f5lA-1dlkB:
35.1		 1f5lA-1dlkB:
33.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		5 / 10 SER B 195
SER B 214
ILE B 212
GLY B 211
GLY B 226
 None
 1.29A 1mehA-1dlkB:
undetectable		 1mehA-1dlkB:
19.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		5 / 6 SER B 190
SER B 195
VAL B 213
GLY B 216
GLY B 226
 None
 0.57A 1tnlA-1dlkB:
36.5		 1tnlA-1dlkB:
43.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		5 / 6 SER B 190
SER B 195
VAL B 213
GLY B 216
GLY B 226
 None
 0.50A 2otvA-1dlkB:
36.7		 2otvA-1dlkB:
43.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		6 / 12 SER B 195
VAL B 213
TRP B 215
GLY B 216
GLY B 226
TYR B 228
 None
 0.30A 2p16A-1dlkB:
35.6		 2p16A-1dlkB:
30.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 8 ILE B 181
GLY B 211
LEU B 209
LEU B 123
 None
 0.86A 2vctA-1dlkB:
undetectable		 2vctA-1dlkB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 8 ILE B 181
GLY B 211
LEU B 209
LEU B 123
 None
 0.87A 2vctB-1dlkB:
0.0		 2vctB-1dlkB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 8 ILE B 181
GLY B 211
LEU B 209
LEU B 123
 None
 0.89A 2vctC-1dlkB:
0.0		 2vctC-1dlkB:
18.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		5 / 8 SER B 190
SER B 195
VAL B 213
GLY B 216
GLY B 226
 None
 0.58A 2vinA-1dlkB:
35.7		 2vinA-1dlkB:
33.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		6 / 12 SER B 195
VAL B 213
TRP B 215
GLY B 216
GLY B 226
TYR B 228
 None
 0.29A 2w26A-1dlkB:
35.5		 2w26A-1dlkB:
30.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		6 / 11 HIS B  57
SER B 190
SER B 195
TRP B 215
GLY B 216
GLY B 226
 None
 0.67A 3gy3A-1dlkB:
35.8		 3gy3A-1dlkB:
43.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 4 SER B 217
SER B 223
THR B 222
SER B 221
 None
 1.43A 3loqA-1dlkB:
0.0		 3loqA-1dlkB:
19.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		5 / 6 SER B 190
SER B 195
VAL B 213
TRP B 215
GLY B 226
 None
 0.69A 3rxfA-1dlkB:
14.0		 3rxfA-1dlkB:
43.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		5 / 6 SER B 195
VAL B 213
TRP B 215
GLY B 216
GLY B 226
 None
 0.26A 3rxfA-1dlkB:
14.0		 3rxfA-1dlkB:
43.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 5 SER B 190
SER B 195
VAL B 213
GLY B 226
 None
 0.70A 3rxhA-1dlkB:
14.2		 3rxhA-1dlkB:
43.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 8 ILE B 212
GLY B 211
VAL B  52
GLN B  30
 None
 0.90A 4acbB-1dlkB:
2.2
4acbC-1dlkB:
2.8		 4acbB-1dlkB:
19.04
4acbC-1dlkB:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 5 SER B 223
GLY B 187
THR B 219
VAL B  17
 None
 1.11A 4eohA-1dlkB:
undetectable		 4eohA-1dlkB:
20.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		5 / 12 HIS B  57
VAL B 213
TRP B 215
GLY B 216
GLY B 226
 None
 0.24A 4rn6B-1dlkB:
29.3		 4rn6B-1dlkB:
35.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		6 / 12 VAL B 238
LEU B 105
VAL B 231
ILE B 212
GLY B 196
VAL B  31
 None
 1.44A 4y8wC-1dlkB:
undetectable		 4y8wC-1dlkB:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1dlk THROMBIN HEAVY CHAIN
(Bos
taurus) 		4 / 4 LEU B 160
GLY B 184
SER B 189
SER B 190
 None
 0.93A 5uunA-1dlkB:
0.0		 5uunA-1dlkB:
19.61