SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dll'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I1E_A_DM2A3001_1
(BOTULINUM NEUROTOXIN
TYPE B)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		5 / 9 GLY A1269
HIS A1271
SER A1287
TRP A1289
TYR A1290
 None
LAT  A2000 ( 4.9A)
GOL  A3000 ( 2.6A)
GOL  A3000 ( 3.3A)
GOL  A3000 ( 4.0A)
 0.44A 1i1eA-1dllA:
0.0		 1i1eA-1dllA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		5 / 11 LEU A1198
PHE A1175
GLY A1210
LEU A1257
LEU A1255
 None
 1.03A 1mx1A-1dllA:
undetectable		 1mx1A-1dllA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		4 / 4 LEU A 889
PRO A 910
ILE A 934
LEU A1072
 None
 1.04A 1ya4B-1dllA:
undetectable		 1ya4B-1dllA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		4 / 4 LEU A 889
PRO A 910
ILE A 934
LEU A1072
 None
 1.02A 1ya4C-1dllA:
undetectable		 1ya4C-1dllA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		4 / 6 GLY A1172
TYR A1202
ASP A1139
ASN A1171
 None
 1.29A 2g72A-1dllA:
undetectable		 2g72A-1dllA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 ILE A 896
ILE A 891
VAL A 915
GLY A 917
 None
 0.78A 4ac9C-1dllA:
undetectable		 4ac9C-1dllA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		5 / 12 GLN A1082
ASN A1078
LEU A1074
ILE A 976
LEU A1000
 None
 1.19A 4k36B-1dllA:
undetectable		 4k36B-1dllA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 GLU A 973
GLN A1013
ILE A1014
LEU A1004
 None
 0.86A 4mj8A-1dllA:
undetectable		 4mj8A-1dllA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 LEU A1130
ASP A1139
ILE A1176
 None
 0.67A 4xi3D-1dllA:
0.0		 4xi3D-1dllA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		4 / 7 ILE A 918
GLY A 917
ASP A1116
PHE A1305
 None
 1.12A 5hieA-1dllA:
undetectable		 5hieA-1dllA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		4 / 6 ASN A1045
THR A1037
ILE A1058
GLU A1057
 None
 1.33A 5uigA-1dllA:
undetectable		 5uigA-1dllA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 VAL A 933
GLU A 932
ILE A 923
 None
 0.59A 6f7lB-1dllA:
undetectable		 6f7lB-1dllA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 1dll TETANUS TOXIN
(Clostridium
tetani) 		4 / 6 ARG A 957
LYS A1030
VAL A1306
PRO A1307
 None
 1.49A 6fgdA-1dllA:
undetectable		 6fgdA-1dllA:
20.37