SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dlm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 8 LEU A 290
ALA A 151
GLY A 119
ILE A 140
 None
 0.68A 1d4yB-1dlmA:
0.0		 1d4yB-1dlmA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		3 / 3 GLU A 106
TYR A 110
PHE A 228
 None
 0.79A 1eqbB-1dlmA:
undetectable		 1eqbB-1dlmA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		3 / 3 GLU A 106
TYR A 110
PHE A 228
 None
 0.79A 1eqbA-1dlmA:
undetectable		 1eqbA-1dlmA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		3 / 3 GLU A 106
TYR A 110
PHE A 228
 None
 0.78A 1eqbD-1dlmA:
undetectable		 1eqbD-1dlmA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		3 / 3 GLU A 106
TYR A 110
PHE A 228
 None
 0.79A 1eqbC-1dlmA:
undetectable		 1eqbC-1dlmA:
23.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		8 / 11 ILE A 105
GLY A 107
PRO A 108
TYR A 164
TYR A 200
ARG A 221
HIS A 224
HIS A 226
 None
None
None
FE  A 400 (-4.1A)
FE  A 400 (-4.4A)
FE  A 400 ( 4.7A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
 0.56A 1s9aA-1dlmA:
27.6		 1s9aA-1dlmA:
30.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		8 / 11 LEU A  73
ILE A 105
GLY A 107
PRO A 108
TYR A 164
TYR A 200
HIS A 224
HIS A 226
 None
None
None
None
FE  A 400 (-4.1A)
FE  A 400 (-4.4A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
 0.58A 1s9aA-1dlmA:
27.6		 1s9aA-1dlmA:
30.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		6 / 12 ASP A  81
TYR A 200
ARG A 221
HIS A 224
HIS A 226
GLN A 240
 None
FE  A 400 (-4.4A)
FE  A 400 ( 4.7A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
None
 1.07A 1s9aB-1dlmA:
27.4		 1s9aB-1dlmA:
30.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		10 / 12 LEU A  73
ILE A 105
GLY A 107
PRO A 108
TYR A 164
TYR A 200
ARG A 221
HIS A 224
HIS A 226
GLN A 240
 None
None
None
None
FE  A 400 (-4.1A)
FE  A 400 (-4.4A)
FE  A 400 ( 4.7A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
None
 0.80A 1s9aB-1dlmA:
27.4		 1s9aB-1dlmA:
30.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		7 / 11 ASP A  81
GLY A 107
PRO A 108
TYR A 164
TYR A 200
HIS A 224
HIS A 226
 None
None
None
FE  A 400 (-4.1A)
FE  A 400 (-4.4A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
 0.97A 1tmxA-1dlmA:
27.8		 1tmxA-1dlmA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		5 / 11 ASP A  81
GLY A 107
PRO A 108
TYR A 200
HIS A 224
 None
None
None
FE  A 400 (-4.4A)
FE  A 400 (-3.4A)
 1.43A 1tmxA-1dlmA:
27.8		 1tmxA-1dlmA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		7 / 11 GLY A 107
PRO A 108
TYR A 164
TYR A 200
ARG A 221
HIS A 224
HIS A 226
 None
None
FE  A 400 (-4.1A)
FE  A 400 (-4.4A)
FE  A 400 ( 4.7A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
 0.55A 1tmxA-1dlmA:
27.8		 1tmxA-1dlmA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		5 / 11 LEU A  73
GLY A 107
ARG A 221
HIS A 224
HIS A 226
 None
None
FE  A 400 ( 4.7A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
 0.99A 1tmxA-1dlmA:
27.8		 1tmxA-1dlmA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		8 / 12 ASP A  81
GLY A 107
PRO A 108
TYR A 164
TYR A 200
ARG A 221
HIS A 224
HIS A 226
 None
None
None
FE  A 400 (-4.1A)
FE  A 400 (-4.4A)
FE  A 400 ( 4.7A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
 0.89A 1tmxB-1dlmA:
27.1		 1tmxB-1dlmA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		5 / 12 LEU A  73
GLY A 107
ARG A 221
HIS A 224
HIS A 226
 None
None
FE  A 400 ( 4.7A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
 0.93A 1tmxB-1dlmA:
27.1		 1tmxB-1dlmA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 8 TYR A 164
TYR A 200
PHE A 253
CYH A 202
 FE  A 400 (-4.1A)
FE  A 400 (-4.4A)
None
None
 1.42A 1xqlA-1dlmA:
undetectable
1xqlB-1dlmA:
undetectable		 1xqlA-1dlmA:
21.14
1xqlB-1dlmA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		5 / 12 PHE A 228
ALA A 254
PRO A 108
GLY A  77
TYR A 110
 None
 1.20A 2igtC-1dlmA:
undetectable		 2igtC-1dlmA:
22.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		8 / 12 ILE A 105
GLY A 107
PRO A 108
TYR A 164
TYR A 200
ARG A 221
HIS A 224
HIS A 226
 None
None
None
FE  A 400 (-4.1A)
FE  A 400 (-4.4A)
FE  A 400 ( 4.7A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
 0.61A 3hgiA-1dlmA:
27.8		 3hgiA-1dlmA:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		7 / 12 LEU A  73
ILE A 105
GLY A 107
PRO A 108
TYR A 164
HIS A 224
HIS A 226
 None
None
None
None
FE  A 400 (-4.1A)
FE  A 400 (-3.4A)
FE  A 400 (-3.1A)
 0.40A 3hgiA-1dlmA:
27.8		 3hgiA-1dlmA:
30.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 6 ARG A 103
HIS A  82
MET A  88
ASP A  89
 None
 1.35A 4cevA-1dlmA:
undetectable
4cevB-1dlmA:
undetectable		 4cevA-1dlmA:
23.37
4cevB-1dlmA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_B_GAIB408_0
(PROTEIN (ARGINASE))		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 5 ARG A 103
HIS A  82
MET A  88
ASP A  89
 None
 1.36A 4cevB-1dlmA:
0.0
4cevC-1dlmA:
0.0		 4cevB-1dlmA:
23.37
4cevC-1dlmA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 6 MET A  88
ASP A  89
ARG A 103
HIS A  82
 None
 1.36A 4cevA-1dlmA:
undetectable
4cevC-1dlmA:
undetectable		 4cevA-1dlmA:
23.37
4cevC-1dlmA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 6 ARG A 103
HIS A  82
MET A  88
ASP A  89
 None
 1.34A 4cevD-1dlmA:
undetectable
4cevE-1dlmA:
undetectable		 4cevD-1dlmA:
23.37
4cevE-1dlmA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 6 ARG A 103
HIS A  82
MET A  88
ASP A  89
 None
 1.37A 4cevE-1dlmA:
undetectable
4cevF-1dlmA:
undetectable		 4cevE-1dlmA:
23.37
4cevF-1dlmA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF412_0
(PROTEIN (ARGINASE))		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 5 MET A  88
ASP A  89
ARG A 103
HIS A  82
 None
 1.37A 4cevD-1dlmA:
0.0
4cevF-1dlmA:
0.0		 4cevD-1dlmA:
23.37
4cevF-1dlmA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 8 ASN A  99
ASP A  89
ASP A  92
LEU A 237
 None
 1.01A 4f8hA-1dlmA:
0.0
4f8hB-1dlmA:
0.0		 4f8hA-1dlmA:
21.45
4f8hB-1dlmA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 8 ASN A  99
ASP A  89
ASP A  92
LEU A 237
 None
 1.05A 4f8hB-1dlmA:
undetectable
4f8hC-1dlmA:
undetectable		 4f8hB-1dlmA:
21.45
4f8hC-1dlmA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 8 ASN A  99
ASP A  89
ASP A  92
LEU A 237
 None
 1.02A 4f8hC-1dlmA:
0.0
4f8hD-1dlmA:
0.0		 4f8hC-1dlmA:
21.45
4f8hD-1dlmA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 8 ASN A  99
ASP A  89
ASP A  92
LEU A 237
 None
 1.01A 4f8hD-1dlmA:
0.0
4f8hE-1dlmA:
0.0		 4f8hD-1dlmA:
21.45
4f8hE-1dlmA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 8 LEU A 237
ASN A  99
ASP A  89
ASP A  92
 None
 1.03A 4f8hA-1dlmA:
0.0
4f8hE-1dlmA:
0.0		 4f8hA-1dlmA:
21.45
4f8hE-1dlmA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		5 / 12 ALA A 158
GLN A 240
ILE A 105
GLY A 219
ASP A 252
 None
 1.33A 4iilA-1dlmA:
undetectable		 4iilA-1dlmA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 8 GLY A  79
ARG A 221
ASP A 252
ASP A  85
 None
FE  A 400 ( 4.7A)
None
None
 0.98A 5vlmB-1dlmA:
undetectable		 5vlmB-1dlmA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		3 / 3 TYR A 190
HIS A 137
MET A 286
 None
 1.22A 6af6A-1dlmA:
0.0		 6af6A-1dlmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		5 / 12 ASP A 185
ASP A 278
ALA A 121
SER A 117
GLY A 138
 None
 1.06A 6b0iB-1dlmA:
undetectable		 6b0iB-1dlmA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 1dlm CATECHOL
1,2-DIOXYGENASE
(Acinetobacter
sp.
ADP1) 		4 / 5 VAL A 153
THR A 184
VAL A 263
LEU A 134
 None
 0.87A 6bqgA-1dlmA:
0.8		 6bqgA-1dlmA:
14.52