SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		4 / 4 THR A 140
VAL A 195
GLY A 182
THR A 181
 None
 0.82A 3cflA-1dlpA:
0.0		 3cflA-1dlpA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		4 / 4 PRO A  14
THR A  16
GLY A  57
THR A  56
 None
 1.10A 3ib1A-1dlpA:
undetectable		 3ib1A-1dlpA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		3 / 3 TRP A  48
TRP A 233
THR A 234
 None
 1.38A 4bboB-1dlpA:
0.2		 4bboB-1dlpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		3 / 3 TRP A 108
TRP A 204
THR A 205
 None
 1.45A 4bboB-1dlpA:
0.2		 4bboB-1dlpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		4 / 7 LEU A  62
LEU A  68
SER A  81
THR A  83
 None
 0.99A 4ikjA-1dlpA:
undetectable
4ikjB-1dlpA:
undetectable		 4ikjA-1dlpA:
18.78
4ikjB-1dlpA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		4 / 7 LEU A  62
LEU A  68
SER A  81
THR A  83
 None
 1.01A 4ikkA-1dlpA:
undetectable
4ikkB-1dlpA:
undetectable		 4ikkA-1dlpA:
18.78
4ikkB-1dlpA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		5 / 12 LEU A 225
PHE A 217
TYR A 228
ASP A 194
GLY A 207
 None
 1.39A 4j7xA-1dlpA:
undetectable		 4j7xA-1dlpA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		5 / 12 LEU A 225
PHE A 217
TYR A 228
ASP A 194
GLY A 207
 None
 1.35A 4j7xF-1dlpA:
undetectable		 4j7xF-1dlpA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		5 / 11 SER A  81
GLY A  82
TRP A 233
GLY A  66
LEU A 147
 None
 1.06A 4kt0A-1dlpA:
undetectable
4kt0J-1dlpA:
undetectable		 4kt0A-1dlpA:
15.85
4kt0J-1dlpA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		4 / 5 ASN A 190
PRO A 189
GLY A 191
ASP A 194
 None
 1.13A 4n48B-1dlpA:
undetectable		 4n48B-1dlpA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		5 / 9 ILE A   3
LEU A  62
GLY A   6
PHE A   5
ALA A  60
 None
 1.38A 5x66C-1dlpA:
undetectable		 5x66C-1dlpA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		5 / 10 SER A  81
GLY A  82
TRP A 233
GLY A  66
LEU A 147
 None
 0.99A 6hqbA-1dlpA:
undetectable
6hqbJ-1dlpA:
undetectable		 6hqbA-1dlpA:
15.52
6hqbJ-1dlpA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1dlp LECTIN SCAFET
PRECURSOR
(Hyacinthoides
hispanica) 		5 / 10 SER A  81
GLY A  82
TRP A 233
GLY A  66
LEU A 149
 None
 1.35A 6hqbA-1dlpA:
undetectable
6hqbJ-1dlpA:
undetectable		 6hqbA-1dlpA:
15.52
6hqbJ-1dlpA:
11.71