SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dly'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		4 / 8 SER A 110
VAL A 108
LEU A  53
VAL A  12
 None
 1.05A 1fduB-1dlyA:
undetectable		 1fduB-1dlyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		5 / 8 PHE A  19
TYR A  20
ILE A  23
PHE A  33
VAL A  83
 None
CYN  A 122 (-4.3A)
None
HEM  A 144 ( 4.4A)
HEM  A 144 (-4.3A)
 0.94A 1fslA-1dlyA:
8.2		 1fslA-1dlyA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		4 / 8 PHE A  19
TYR A  20
ILE A  23
VAL A  83
 None
CYN  A 122 (-4.3A)
None
HEM  A 144 (-4.3A)
 0.58A 1fslB-1dlyA:
8.6		 1fslB-1dlyA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_A_T44A128_1
(TRANSTHYRETIN)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		4 / 4 LYS A   5
LEU A   2
ALA A   4
LEU A  53
 SO4  A 123 ( 4.0A)
SO4  A 123 (-4.5A)
None
None
 1.30A 2roxA-1dlyA:
undetectable		 2roxA-1dlyA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		5 / 12 PHE A  19
TYR A  20
PHE A  33
VAL A  83
LEU A  87
 None
CYN  A 122 (-4.3A)
HEM  A 144 ( 4.4A)
HEM  A 144 (-4.3A)
None
 0.88A 4g1bA-1dlyA:
10.2		 4g1bA-1dlyA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		5 / 9 PHE A  19
TYR A  20
LEU A  49
VAL A  83
LEU A  87
 None
CYN  A 122 (-4.3A)
None
HEM  A 144 (-4.3A)
None
 1.11A 4g1bC-1dlyA:
3.7		 4g1bC-1dlyA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		5 / 12 PHE A  19
TYR A  20
PHE A  33
LEU A  49
LEU A  87
 None
CYN  A 122 (-4.3A)
HEM  A 144 ( 4.4A)
None
None
 1.15A 4g1bD-1dlyA:
10.0		 4g1bD-1dlyA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		4 / 8 ALA A  15
THR A 111
VAL A 115
PHE A  80
 None
HEM  A 144 ( 4.1A)
None
HEM  A 144 (-4.4A)
 0.77A 4ltwA-1dlyA:
undetectable		 4ltwA-1dlyA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		4 / 8 LEU A  91
ASP A 100
ALA A 104
VAL A 107
 None
 0.71A 4zbqA-1dlyA:
1.7		 4zbqA-1dlyA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		4 / 4 LYS A   5
LEU A   2
ALA A   4
LEU A  53
 SO4  A 123 ( 4.0A)
SO4  A 123 (-4.5A)
None
None
 1.40A 6gnrA-1dlyA:
undetectable		 6gnrA-1dlyA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 1dly HEMOGLOBIN
(Chlamydomonas
moewusii) 		4 / 4 LYS A   5
LEU A   2
ALA A   4
LEU A  53
 SO4  A 123 ( 4.0A)
SO4  A 123 (-4.5A)
None
None
 1.41A 6gnrB-1dlyA:
undetectable		 6gnrB-1dlyA:
22.64