SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dm1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		5 / 11 ALA A 143
LEU A  71
LEU A 136
GLY A 135
ALA A  78
 None
HEM  A 148 ( 4.4A)
None
None
None
 1.00A 1b02A-1dm1A:
undetectable		 1b02A-1dm1A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		5 / 12 ILE A 138
ILE A 137
ALA A 140
MET A  84
LEU A   2
 None
 1.21A 1xzxX-1dm1A:
undetectable		 1xzxX-1dm1A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		3 / 3 PHE A  91
PHE A 105
PHE A 134
 HEM  A 148 (-4.6A)
HEM  A 148 (-4.4A)
None
 0.88A 2od9A-1dm1A:
undetectable		 2od9A-1dm1A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		5 / 12 LEU A  29
LEU A  32
PHE A  33
ILE A  67
VAL A 100
 None
None
None
HEM  A 148 (-4.2A)
HEM  A 148 (-4.5A)
 1.08A 2pnjA-1dm1A:
undetectable		 2pnjA-1dm1A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		5 / 12 LEU A 133
ILE A 137
ALA A  10
PHE A  91
MET A  84
 None
None
None
HEM  A 148 (-4.6A)
None
 1.08A 2qo4A-1dm1A:
undetectable		 2qo4A-1dm1A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		3 / 3 PHE A  91
PHE A 105
PHE A 134
 HEM  A 148 (-4.6A)
HEM  A 148 (-4.4A)
None
 0.88A 2qqgA-1dm1A:
undetectable		 2qqgA-1dm1A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		5 / 12 HIS A  95
SER A  39
ALA A  40
ILE A  67
MET A 111
 HEM  A 148 (-3.3A)
HEM  A 148 (-4.0A)
None
HEM  A 148 (-4.2A)
None
 1.10A 2xkwB-1dm1A:
undetectable		 2xkwB-1dm1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		5 / 7 PRO A 123
GLY A 125
ALA A 126
ALA A   5
ASP A   8
 None
 1.13A 3ur0B-1dm1A:
undetectable		 3ur0B-1dm1A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		5 / 12 LEU A  88
ALA A  10
LYS A 132
ILE A 138
GLY A 101
 None
 1.25A 4l9qA-1dm1A:
2.4		 4l9qA-1dm1A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 1dm1 MYOGLOBIN
(Aplysia
limacina) 		3 / 3 THR A  66
THR A  69
PHE A  74
 HEM  A 148 (-4.5A)
None
None
 0.91A 5cxvA-1dm1A:
0.0		 5cxvA-1dm1A:
14.96