SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dmg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_G_ACTG3009_0 (BETA-CARBONIC ANHYDRASE)	1dmg	RIBOSOMAL PROTEIN L4 (Thermotoga maritima)	4 / 5	GLY A 171 LEU A 139 THR A 136 VAL A 177	None	1.13A	1ekjF-1dmgA: undetectable 1ekjG-1dmgA: undetectable	1ekjF-1dmgA: 20.16 1ekjG-1dmgA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1101_1 (STRUCTURAL PROTEIN VP3)	1dmg	RIBOSOMAL PROTEIN L4 (Thermotoga maritima)	3 / 3	GLU A 161 ASP A 183 ASP A 216	None CIT A 510 (-2.9A) None	0.63A	3jb2A-1dmgA: undetectable	3jb2A-1dmgA: 12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TIY_A_OAQA302_0 (SULFOTRANSFERASE)	1dmg	RIBOSOMAL PROTEIN L4 (Thermotoga maritima)	5 / 11	PRO A 185 ILE A 180 MET A 217 LEU A 213 THR A 214	CIT A 510 (-3.5A) None None None None	1.20A	5tiyA-1dmgA: 0.0	5tiyA-1dmgA: 18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UHB_C_RFPC1201_2 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA)	1dmg	RIBOSOMAL PROTEIN L4 (Thermotoga maritima)	3 / 3	PHE A 203 ASP A 38 LEU A 108	None	0.65A	5uhbC-1dmgA: 0.0	5uhbC-1dmgA: 11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UHC_C_RFPC1201_2 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA)	1dmg	RIBOSOMAL PROTEIN L4 (Thermotoga maritima)	3 / 3	PHE A 203 ASP A 38 LEU A 108	None	0.66A	5uhcC-1dmgA: 0.0	5uhcC-1dmgA: 11.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EKJ_G_ACTG3009_0","BETA-CARBONIC ANHYDRASE","1dmg","RIBOSOMAL PROTEIN L4","Thermotoga maritima",4,"GLY A 171;LEU A 139;THR A 136;VAL A 177","None","1.13A","1ekjF-1dmgA:undetectable;1ekjG-1dmgA:undetectable","1ekjF-1dmgA:20.16;1ekjG-1dmgA:20.16"],["3JB2_A_SAMA1101_1","STRUCTURAL PROTEIN VP3","1dmg","RIBOSOMAL PROTEIN L4","Thermotoga maritima",3,"GLU A 161;ASP A 183;ASP A 216","None;CIT A 510 (-2.9A);None","0.63A","3jb2A-1dmgA:undetectable","3jb2A-1dmgA:12.25"],["5TIY_A_OAQA302_0","SULFOTRANSFERASE","1dmg","RIBOSOMAL PROTEIN L4","Thermotoga maritima",5,"PRO A 185;ILE A 180;MET A 217;LEU A 213;THR A 214","CIT A 510 (-3.5A);None;None;None;None","1.20A","5tiyA-1dmgA:0.0","5tiyA-1dmgA:18.29"],["5UHB_C_RFPC1201_2","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA","1dmg","RIBOSOMAL PROTEIN L4","Thermotoga maritima",3,"PHE A 203;ASP A  38;LEU A 108","None","0.65A","5uhbC-1dmgA:0.0","5uhbC-1dmgA:11.23"],["5UHC_C_RFPC1201_2","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA","1dmg","RIBOSOMAL PROTEIN L4","Thermotoga maritima",3,"PHE A 203;ASP A  38;LEU A 108","None","0.66A","5uhcC-1dmgA:0.0","5uhcC-1dmgA:11.23"]]