SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dms'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 8 GLY A 364
TRP A 171
GLY A 363
TYR A 358
 None
 0.91A 1dbbH-1dmsA:
0.3
1dbbL-1dmsA:
undetectable		 1dbbH-1dmsA:
13.06
1dbbL-1dmsA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 4 ARG A 309
ALA A 308
ALA A 290
GLU A 302
 None
 1.23A 1e7bA-1dmsA:
undetectable		 1e7bA-1dmsA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 7 VAL A 164
VAL A 338
TYR A 603
ARG A 326
 None
None
None
PGD  A 783 ( 2.6A)
 1.30A 1t46A-1dmsA:
undetectable		 1t46A-1dmsA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 ASP A 613
TYR A 612
GLU A 331
 None
 0.83A 1vm1A-1dmsA:
0.0		 1vm1A-1dmsA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 ASP A 629
GLU A 760
ARG A 693
 None
 0.88A 1wopA-1dmsA:
0.0		 1wopA-1dmsA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_B_ROFB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 5 THR A  39
MET A  41
GLN A 193
PHE A 645
 None
None
PGD  A 783 (-4.1A)
None
 1.26A 1xmuB-1dmsA:
undetectable		 1xmuB-1dmsA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 7 GLY A  11
PRO A 199
ASP A  35
THR A  39
 None
 1.09A 2aouB-1dmsA:
undetectable		 2aouB-1dmsA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 12 GLY A 754
ASP A 441
GLY A 744
PRO A 398
VAL A 399
 PGD  A 782 (-3.8A)
None
None
None
None
 0.87A 2q5kB-1dmsA:
undetectable		 2q5kB-1dmsA:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 11 ASN A 416
VAL A 153
PHE A 413
TYR A 612
GLU A 331
 None
 1.44A 3bgrA-1dmsA:
0.0
3bgrB-1dmsA:
0.4		 3bgrA-1dmsA:
21.80
3bgrB-1dmsA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 8 GLY A 321
ALA A 185
ASP A 221
LEU A 318
VAL A 244
 PGD  A 783 (-3.6A)
PGD  A 783 (-3.3A)
PGD  A 783 (-2.9A)
None
None
 1.29A 3em6A-1dmsA:
undetectable		 3em6A-1dmsA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 10 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.17A 3fhjA-1dmsA:
undetectable		 3fhjA-1dmsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 10 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.17A 3fhjB-1dmsA:
undetectable		 3fhjB-1dmsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 10 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fhjC-1dmsA:
undetectable		 3fhjC-1dmsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.17A 3fhjD-1dmsA:
undetectable		 3fhjD-1dmsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 10 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fhjE-1dmsA:
undetectable		 3fhjE-1dmsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fhjF-1dmsA:
undetectable		 3fhjF-1dmsA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.23A 3fi0A-1dmsA:
undetectable		 3fi0A-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.23A 3fi0C-1dmsA:
undetectable		 3fi0C-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.22A 3fi0D-1dmsA:
undetectable		 3fi0D-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.21A 3fi0F-1dmsA:
0.8		 3fi0F-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fi0H-1dmsA:
undetectable		 3fi0H-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 8 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.24A 3fi0I-1dmsA:
undetectable		 3fi0I-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.23A 3fi0J-1dmsA:
1.3		 3fi0J-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.20A 3fi0K-1dmsA:
undetectable		 3fi0K-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.18A 3fi0L-1dmsA:
undetectable		 3fi0L-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.20A 3fi0M-1dmsA:
undetectable		 3fi0M-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.22A 3fi0N-1dmsA:
undetectable		 3fi0N-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.20A 3fi0O-1dmsA:
undetectable		 3fi0O-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 GLY A 699
VAL A 663
ILE A 713
VAL A 689
VAL A 761
 None
 1.21A 3fi0R-1dmsA:
undetectable		 3fi0R-1dmsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 12 GLY A 364
GLY A 363
PRO A 366
PHE A 578
PRO A 172
 None
 0.92A 3jayA-1dmsA:
2.7		 3jayA-1dmsA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 6 ILE A 484
PRO A 119
ASP A  35
GLY A  11
 None
 0.95A 3n3iA-1dmsA:
0.0		 3n3iA-1dmsA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 12 TYR A 114
GLY A 115
GLY A 142
ALA A 400
PHE A 110
 MM4  A 784 ( 4.3A)
PGD  A 782 (-3.4A)
None
None
None
 1.24A 3qowA-1dmsA:
undetectable		 3qowA-1dmsA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 7 VAL A 158
LEU A 748
ASN A 416
MET A 610
ILE A 607
 None
 1.34A 3rfmA-1dmsA:
undetectable		 3rfmA-1dmsA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 LEU A 279
HIS A 252
MET A 280
 None
 0.84A 3thrD-1dmsA:
undetectable		 3thrD-1dmsA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 ARG A 401
PRO A 423
PHE A 413
 None
 0.74A 3thrC-1dmsA:
0.0		 3thrC-1dmsA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 6 ILE A 154
ILE A 220
TRP A 184
MET A 324
 None
PGD  A 783 (-4.7A)
None
None
 1.49A 3welA-1dmsA:
undetectable		 3welA-1dmsA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 7 GLY A 716
GLY A 717
TYR A 733
GLU A 715
 None
None
None
PGD  A 782 (-3.9A)
 1.03A 4fgkB-1dmsA:
undetectable		 4fgkB-1dmsA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 12 LEU A 340
THR A 339
VAL A 255
TYR A 260
ILE A 265
 None
 1.12A 4g1bA-1dmsA:
2.1		 4g1bA-1dmsA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 10 ALA A 448
LEU A 406
VAL A 425
ARG A 442
ILE A 397
 None
 0.99A 4j14A-1dmsA:
0.0		 4j14A-1dmsA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 8 ASP A 731
VAL A 689
GLY A 699
VAL A 736
ILE A 696
 None
 1.44A 4ll3A-1dmsA:
1.8		 4ll3A-1dmsA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 ALA A 448
GLN A 440
GLY A 754
 None
PGD  A 782 (-4.4A)
PGD  A 782 (-3.8A)
 0.62A 4odoC-1dmsA:
0.0		 4odoC-1dmsA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 7 GLU A 530
HIS A 123
LEU A 128
SER A 540
 None
 0.94A 4pfjA-1dmsA:
2.8		 4pfjA-1dmsA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 PRO A  58
MET A  59
TYR A  57
 None
 1.09A 4qa0A-1dmsA:
undetectable		 4qa0A-1dmsA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 PRO A  58
MET A  59
TYR A  57
 None
 1.05A 4qa2B-1dmsA:
undetectable		 4qa2B-1dmsA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 4 SER A 323
ASP A 221
ASP A 234
ASP A 243
 PGD  A 783 (-2.6A)
PGD  A 783 (-2.9A)
None
PGD  A 783 (-2.8A)
 1.35A 4uciA-1dmsA:
2.5		 4uciA-1dmsA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		4 / 4 SER A 323
ASP A 221
ASP A 234
ASP A 243
 PGD  A 783 (-2.6A)
PGD  A 783 (-2.9A)
None
PGD  A 783 (-2.8A)
 1.34A 4uciB-1dmsA:
0.0		 4uciB-1dmsA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 12 LEU A 174
VAL A 217
VAL A 219
PHE A 183
MET A 181
 None
 1.15A 4y0pA-1dmsA:
0.0		 4y0pA-1dmsA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 ILE A 198
PRO A 199
ILE A 487
 None
 0.41A 5hw8F-1dmsA:
0.0		 5hw8F-1dmsA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 9 LEU A 307
ALA A 308
PHE A 311
VAL A 182
ILE A 220
 None
None
None
None
PGD  A 783 (-4.7A)
 1.20A 5om2A-1dmsA:
undetectable
5om2B-1dmsA:
undetectable		 5om2A-1dmsA:
7.22
5om2B-1dmsA:
4.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 12 ASP A 459
LEU A 657
ASP A  47
SER A 118
ARG A 658
 PGD  A 782 (-3.0A)
None
None
PGD  A 782 (-2.6A)
None
 1.28A 5syfB-1dmsA:
2.2		 5syfB-1dmsA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		5 / 12 GLY A 751
VAL A 425
VAL A 140
GLY A 142
ILE A 397
 None
 1.05A 5vopA-1dmsA:
undetectable		 5vopA-1dmsA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1dms DMSO REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 GLY A 206
VAL A 217
MET A 181
 None
 0.46A 5ycpA-1dmsA:
undetectable		 5ycpA-1dmsA:
6.92