SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dmu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		4 / 7 ASN A 249
GLY A 251
ASP A 255
TYR A 258
 None
 0.95A 1bu5A-1dmuA:
undetectable		 1bu5A-1dmuA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 10 LEU A 121
VAL A 106
ILE A 104
LEU A  38
VAL A 141
 None
 1.13A 1cqpA-1dmuA:
undetectable
1cqpB-1dmuA:
undetectable		 1cqpA-1dmuA:
20.78
1cqpB-1dmuA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		4 / 7 VAL A 141
LEU A 121
VAL A 106
LEU A  38
 None
 0.78A 1cqpA-1dmuA:
undetectable
1cqpB-1dmuA:
undetectable		 1cqpA-1dmuA:
20.78
1cqpB-1dmuA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 12 PRO A 290
LEU A 285
SER A 239
LEU A  35
ILE A 288
 None
 1.30A 1lbcA-1dmuA:
undetectable
1lbcC-1dmuA:
undetectable		 1lbcA-1dmuA:
23.81
1lbcC-1dmuA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 12 ILE A 288
PRO A 290
LEU A 285
SER A 239
LEU A  35
 None
 1.37A 1lbcA-1dmuA:
undetectable
1lbcC-1dmuA:
undetectable		 1lbcA-1dmuA:
23.81
1lbcC-1dmuA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 8 ILE A 214
LEU A 237
ILE A  42
GLU A  40
VAL A  41
 None
 1.39A 1linA-1dmuA:
undetectable		 1linA-1dmuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		3 / 3 THR A 113
LEU A 111
LEU A 120
 None
 0.54A 1mz9C-1dmuA:
undetectable		 1mz9C-1dmuA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		4 / 6 PHE A 262
VAL A 278
LEU A 157
PHE A 247
 None
 1.07A 1wrlB-1dmuA:
undetectable		 1wrlB-1dmuA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 12 GLY A 243
LEU A 198
PRO A 208
ILE A 206
PHE A 140
 None
 0.92A 1zq9B-1dmuA:
undetectable		 1zq9B-1dmuA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		3 / 3 PRO A 216
GLY A  86
TYR A  53
 None
 0.72A 2vouA-1dmuA:
undetectable		 2vouA-1dmuA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		3 / 3 PRO A 216
GLY A  86
TYR A  53
 None
 0.71A 2vouB-1dmuA:
undetectable		 2vouB-1dmuA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		3 / 3 PRO A 216
GLY A  86
TYR A  53
 None
 0.72A 2vouC-1dmuA:
undetectable		 2vouC-1dmuA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 11 PRO A 290
LEU A 285
SER A 239
LEU A  35
ILE A 288
 None
 1.35A 3h6tA-1dmuA:
undetectable
3h6tC-1dmuA:
undetectable		 3h6tA-1dmuA:
23.81
3h6tC-1dmuA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 11 ILE A 288
PRO A 290
LEU A 285
SER A 239
LEU A  35
 None
 1.41A 3h6tA-1dmuA:
undetectable
3h6tC-1dmuA:
undetectable		 3h6tA-1dmuA:
23.81
3h6tC-1dmuA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 12 PRO A 290
LEU A 285
SER A 239
LEU A  35
ILE A 288
 None
 1.35A 3iltB-1dmuA:
undetectable
3iltE-1dmuA:
undetectable		 3iltB-1dmuA:
22.44
3iltE-1dmuA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 10 ILE A 288
PRO A 290
LEU A 285
SER A 239
LEU A  35
 None
 1.39A 3iltB-1dmuA:
undetectable
3iltE-1dmuA:
undetectable		 3iltB-1dmuA:
22.44
3iltE-1dmuA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		3 / 3 TYR A 258
MET A 293
LEU A  32
 None
 0.98A 3vw1D-1dmuA:
0.0		 3vw1D-1dmuA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		4 / 8 ILE A 200
PRO A 208
PHE A 133
LEU A  20
 None
 0.92A 4qopC-1dmuA:
undetectable		 4qopC-1dmuA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 12 LEU A 155
LEU A 261
VAL A 292
ALA A 238
ILE A 288
 None
 1.01A 4x20B-1dmuA:
undetectable		 4x20B-1dmuA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		3 / 3 ILE A 206
MET A 139
ASP A 135
 None
 0.81A 5h2uA-1dmuA:
undetectable		 5h2uA-1dmuA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 10 GLY A 245
GLY A 251
LEU A 246
LEU A 261
TYR A 258
 None
 1.22A 5hwkA-1dmuA:
undetectable		 5hwkA-1dmuA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 10 GLY A 245
GLY A 251
LEU A 246
LEU A 261
TYR A 258
 None
 1.21A 5hwkB-1dmuA:
undetectable		 5hwkB-1dmuA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		4 / 5 PRO A 216
VAL A  90
GLY A  34
VAL A 141
 None
 1.09A 6ak3B-1dmuA:
0.3		 6ak3B-1dmuA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 12 PRO A 197
ILE A  30
LEU A 244
LEU A 121
THR A 122
 None
 1.03A 6b52A-1dmuA:
undetectable		 6b52A-1dmuA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 1dmu BGLI RESTRICTION
ENDONUCLEASE
(Bacillus
subtilis) 		5 / 12 ASN A  36
ILE A 126
VAL A 210
ILE A 137
PRO A 250
 None
 1.10A 6hlpA-1dmuA:
undetectable		 6hlpA-1dmuA:
20.12