SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dnl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1dnl PYRIDOXINE
5'-PHOSPHATE OXIDASE
(Escherichia
coli) 		3 / 3 GLN A 146
LYS A 145
VAL A 143
 FMN  A 250 (-3.1A)
None
None
 0.90A 2jfaB-1dnlA:
0.0		 2jfaB-1dnlA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 1dnl PYRIDOXINE
5'-PHOSPHATE OXIDASE
(Escherichia
coli) 		4 / 6 LEU A 174
HIS A 131
MET A 127
THR A 123
 None
 1.35A 3thrB-1dnlA:
0.0		 3thrB-1dnlA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 1dnl PYRIDOXINE
5'-PHOSPHATE OXIDASE
(Escherichia
coli) 		5 / 12 PHE A  35
LEU A  34
GLN A  41
THR A  51
VAL A 112
 None
 1.17A 4wnwA-1dnlA:
0.0		 4wnwA-1dnlA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1dnl PYRIDOXINE
5'-PHOSPHATE OXIDASE
(Escherichia
coli) 		5 / 10 PRO A  28
LEU A  32
PHE A  35
PHE A 103
VAL A 112
 None
 1.41A 5m0oA-1dnlA:
0.0		 5m0oA-1dnlA:
19.39