SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1do6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		3 / 3 GLU A  14
HIS A  41
HIS A  16
 FE  A 200 (-2.9A)
FE  A 200 (-3.3A)
FE  A 200 (-3.3A)
 0.50A 1oe2A-1do6A:
undetectable		 1oe2A-1do6A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  16
HIS A  41
HIS A  47
HIS A 114
 FE  A 200 (-3.3A)
FE  A 200 (-3.3A)
FE  A 200 (-3.4A)
FE  A 200 (-3.2A)
 1.35A 2fqgA-1do6A:
undetectable		 2fqgA-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		3 / 3 LYS A 101
TYR A  65
PRO A  58
 None
 1.30A 2j9cC-1do6A:
undetectable		 2j9cC-1do6A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB601_0
(LACCASE-1)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.38A 3qpkB-1do6A:
undetectable		 3qpkB-1do6A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 5 LEU A 123
GLY A 103
PHE A  56
ARG A  24
 None
 0.92A 3smtA-1do6A:
undetectable		 3smtA-1do6A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  16
HIS A  41
HIS A  47
HIS A 114
 FE  A 200 (-3.3A)
FE  A 200 (-3.3A)
FE  A 200 (-3.4A)
FE  A 200 (-3.2A)
 1.36A 4ef3A-1do6A:
undetectable		 4ef3A-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA504_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.19A 5mejA-1do6A:
undetectable		 5mejA-1do6A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA504_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.21A 5mewA-1do6A:
undetectable		 5mewA-1do6A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA504_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.22A 5mhuA-1do6A:
undetectable		 5mhuA-1do6A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA504_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.23A 5mhvA-1do6A:
undetectable		 5mhvA-1do6A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.22A 5mhwA-1do6A:
undetectable		 5mhwA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.22A 5mhxA-1do6A:
undetectable		 5mhxA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.23A 5mhyA-1do6A:
undetectable		 5mhyA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.23A 5mhzA-1do6A:
undetectable		 5mhzA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.23A 5mi1A-1do6A:
undetectable		 5mi1A-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.23A 5mi2A-1do6A:
undetectable		 5mi2A-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.23A 5miaA-1do6A:
undetectable		 5miaA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.23A 5mibA-1do6A:
undetectable		 5mibA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.23A 5micA-1do6A:
undetectable		 5micA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.24A 5midA-1do6A:
undetectable		 5midA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.23A 5mieA-1do6A:
undetectable		 5mieA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA604_0
(LACCASE 2)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
ILE A 113
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
None
FE  A 200 (-3.2A)
 1.24A 5migA-1do6A:
undetectable		 5migA-1do6A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  16
CYH A 111
HIS A  47
HIS A  41
 FE  A 200 (-3.3A)
FE  A 200 (-2.4A)
FE  A 200 (-3.4A)
FE  A 200 (-3.3A)
 1.15A 5zrdA-1do6A:
undetectable		 5zrdA-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A  47
CYH A 111
HIS A  16
HIS A 114
 FE  A 200 (-3.4A)
FE  A 200 (-2.4A)
FE  A 200 (-3.3A)
FE  A 200 (-3.2A)
 1.49A 5zrdA-1do6A:
undetectable		 5zrdA-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A 114
CYH A 111
HIS A  47
HIS A  16
 FE  A 200 (-3.2A)
FE  A 200 (-2.4A)
FE  A 200 (-3.4A)
FE  A 200 (-3.3A)
 1.48A 5zrdA-1do6A:
undetectable		 5zrdA-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 4 HIS A 114
CYH A 111
HIS A  47
HIS A  41
 FE  A 200 (-3.2A)
FE  A 200 (-2.4A)
FE  A 200 (-3.4A)
FE  A 200 (-3.3A)
 1.24A 5zrdA-1do6A:
undetectable		 5zrdA-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 5 HIS A  16
CYH A 111
HIS A  47
HIS A  41
 FE  A 200 (-3.3A)
FE  A 200 (-2.4A)
FE  A 200 (-3.4A)
FE  A 200 (-3.3A)
 1.17A 5zrdB-1do6A:
2.8		 5zrdB-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 5 HIS A 114
CYH A 111
HIS A  47
HIS A  41
 FE  A 200 (-3.2A)
FE  A 200 (-2.4A)
FE  A 200 (-3.4A)
FE  A 200 (-3.3A)
 1.17A 5zrdB-1do6A:
2.8		 5zrdB-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 5 HIS A  16
CYH A 111
HIS A  47
HIS A  41
 FE  A 200 (-3.3A)
FE  A 200 (-2.4A)
FE  A 200 (-3.4A)
FE  A 200 (-3.3A)
 1.20A 5zrdC-1do6A:
3.6		 5zrdC-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 5 HIS A 114
CYH A 111
HIS A  47
HIS A  41
 FE  A 200 (-3.2A)
FE  A 200 (-2.4A)
FE  A 200 (-3.4A)
FE  A 200 (-3.3A)
 1.26A 5zrdC-1do6A:
3.6		 5zrdC-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 5 HIS A  16
CYH A 111
HIS A  47
HIS A  41
 FE  A 200 (-3.3A)
FE  A 200 (-2.4A)
FE  A 200 (-3.4A)
FE  A 200 (-3.3A)
 1.14A 5zrdD-1do6A:
3.5		 5zrdD-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		4 / 5 HIS A 114
CYH A 111
HIS A  47
HIS A  41
 FE  A 200 (-3.2A)
FE  A 200 (-2.4A)
FE  A 200 (-3.4A)
FE  A 200 (-3.3A)
 1.18A 5zrdD-1do6A:
3.5		 5zrdD-1do6A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 1do6 SUPEROXIDE REDUCTASE
(Pyrococcus
furiosus) 		3 / 3 ILE A  92
ASN A  43
CYH A 111
 None
None
FE  A 200 (-2.4A)
 0.89A 6bp4A-1do6A:
0.0		 6bp4A-1do6A:
17.38