SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1dov ALPHA-CATENIN
(Mus
musculus) 		5 / 11 LEU A 221
VAL A 218
ARG A 241
ILE A 161
ALA A 179
 None
 1.03A 2zbzA-1dovA:
undetectable		 2zbzA-1dovA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_B_017B203_1
(PROTEASE)		 1dov ALPHA-CATENIN
(Mus
musculus) 		4 / 5 PRO A 115
LYS A 120
ARG A 121
GLY A 122
 None
 1.49A 3s53B-1dovA:
undetectable		 3s53B-1dovA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 1dov ALPHA-CATENIN
(Mus
musculus) 		4 / 7 LEU A 214
ALA A 191
VAL A 147
ILE A 255
 None
 0.87A 3wsjB-1dovA:
undetectable		 3wsjB-1dovA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1dov ALPHA-CATENIN
(Mus
musculus) 		4 / 6 VAL A  91
LEU A 141
LEU A 138
ARG A 137
 None
 0.96A 6e43A-1dovA:
1.3		 6e43A-1dovA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1dov ALPHA-CATENIN
(Mus
musculus) 		4 / 6 VAL A  91
LEU A 141
LEU A 138
ARG A 137
 None
 0.95A 6e43B-1dovA:
2.2		 6e43B-1dovA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1dov ALPHA-CATENIN
(Mus
musculus) 		4 / 6 VAL A  91
LEU A 141
LEU A 138
ARG A 137
 None
 0.96A 6e43C-1dovA:
0.7		 6e43C-1dovA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1dov ALPHA-CATENIN
(Mus
musculus) 		4 / 6 VAL A  91
LEU A 141
LEU A 138
ARG A 137
 None
 0.97A 6e43D-1dovA:
1.4		 6e43D-1dovA:
19.89