SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1dp2 RHODANESE
(Bos
taurus) 		5 / 9 ASP A  99
ALA A 108
VAL A 125
GLY A 104
GLY A 129
 None
 1.19A 1bcuH-1dp2A:
undetectable		 1bcuH-1dp2A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 1dp2 RHODANESE
(Bos
taurus) 		4 / 6 PHE A 130
LEU A  15
VAL A  19
VAL A 140
 None
 1.09A 1e7aB-1dp2A:
0.0		 1e7aB-1dp2A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_B_DVAB6_0
(GRAMICIDIN A)		 1dp2 RHODANESE
(Bos
taurus) 		4 / 4 VAL A  96
TRP A 112
ALA A   8
VAL A 123
 None
 1.30A 1gmkA-1dp2A:
undetectable
1gmkB-1dp2A:
undetectable		 1gmkA-1dp2A:
4.86
1gmkB-1dp2A:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 1dp2 RHODANESE
(Bos
taurus) 		6 / 12 GLY A 273
GLY A 250
ASP A 272
THR A 163
GLU A 165
ARG A 248
 None
 1.47A 2gluA-1dp2A:
undetectable		 2gluA-1dp2A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 1dp2 RHODANESE
(Bos
taurus) 		4 / 6 LEU A 239
ILE A 256
VAL A 268
ALA A 260
 None
 0.82A 2j5mA-1dp2A:
0.0		 2j5mA-1dp2A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 1dp2 RHODANESE
(Bos
taurus) 		5 / 12 ALA A 245
LEU A 161
LEU A 243
SER A 207
GLY A 250
 None
 1.01A 3g2oA-1dp2A:
undetectable		 3g2oA-1dp2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1dp2 RHODANESE
(Bos
taurus) 		3 / 3 SER A  76
ASP A  65
ASP A  82
 None
 0.78A 3iv6A-1dp2A:
undetectable		 3iv6A-1dp2A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1dp2 RHODANESE
(Bos
taurus) 		3 / 3 SER A  76
ASP A  65
ASP A  82
 None
 0.73A 3iv6C-1dp2A:
undetectable		 3iv6C-1dp2A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 1dp2 RHODANESE
(Bos
taurus) 		4 / 6 LEU A 199
GLU A 193
PRO A 192
ARG A 248
 None
 1.42A 3ltwA-1dp2A:
undetectable		 3ltwA-1dp2A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1dp2 RHODANESE
(Bos
taurus) 		5 / 12 TYR A  98
GLU A 136
GLY A 104
SER A 105
ASP A 102
 None
 1.17A 3ou6D-1dp2A:
undetectable		 3ou6D-1dp2A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1dp2 RHODANESE
(Bos
taurus) 		5 / 10 THR A 141
TYR A  47
LEU A  15
VAL A  96
VAL A  19
 None
 1.46A 3u9fE-1dp2A:
0.0		 3u9fE-1dp2A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 1dp2 RHODANESE
(Bos
taurus) 		4 / 6 ASP A  99
ASP A 102
ARG A  41
GLU A  46
 None
 1.20A 4eysA-1dp2A:
undetectable		 4eysA-1dp2A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 1dp2 RHODANESE
(Bos
taurus) 		3 / 3 THR A  93
HIS A 120
ASN A  91
 None
 0.64A 5n4tA-1dp2A:
0.0		 5n4tA-1dp2A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1dp2 RHODANESE
(Bos
taurus) 		5 / 11 LEU A 126
GLY A 104
SER A  11
LEU A  15
ARG A  50
 None
 1.07A 5o96A-1dp2A:
undetectable
5o96B-1dp2A:
undetectable		 5o96A-1dp2A:
24.49
5o96B-1dp2A:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1dp2 RHODANESE
(Bos
taurus) 		5 / 12 ALA A 257
PRO A 266
GLY A 264
ALA A 253
ARG A 110
 None
 1.28A 5zvgA-1dp2A:
undetectable		 5zvgA-1dp2A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1dp2 RHODANESE
(Bos
taurus) 		5 / 12 ALA A 257
PRO A 266
GLY A 264
ALA A 253
ARG A 110
 None
 1.28A 5zvgB-1dp2A:
undetectable		 5zvgB-1dp2A:
22.28