SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dpy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		3 / 3 ASP A  94
PHE A  89
ASN A  64
 None
 0.88A 1sg9B-1dpyA:
undetectable		 1sg9B-1dpyA:
15.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD7_A_NFLA2001_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		6 / 9 LEU A   2
LYS A   6
ILE A   9
TRP A  19
GLY A  30
PHE A 101
 None
None
None
None
NA  A 150 (-4.5A)
None
 0.92A 1td7A-1dpyA:
20.0		 1td7A-1dpyA:
61.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  63
 NA  A 150 (-4.5A)
None
NA  A 150 (-2.5A)
None
None
 0.70A 1th6A-1dpyA:
17.3		 1th6A-1dpyA:
39.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  63
 NA  A 150 (-4.5A)
None
NA  A 150 (-2.5A)
None
None
 0.71A 2armA-1dpyA:
17.3		 2armA-1dpyA:
39.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		6 / 11 ILE A   9
TYR A  25
GLY A  30
LEU A  41
PHE A 101
TYR A 106
 None
None
NA  A 150 (-4.5A)
None
None
None
 0.58A 2azyA-1dpyA:
17.4		 2azyA-1dpyA:
48.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 6 LEU A   2
HIS A  48
ASP A  49
TYR A  52
 None
None
NA  A 150 (-2.5A)
None
 0.48A 2dpzA-1dpyA:
17.5		 2dpzA-1dpyA:
39.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 8 LYS A   1
HIS A  48
ASP A  94
ALA A  55
 None
 1.39A 2rk8A-1dpyA:
2.1		 2rk8A-1dpyA:
11.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
NA  A 150 (-2.5A)
None
None
 0.64A 3fo7A-1dpyA:
17.3		 3fo7A-1dpyA:
39.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 5 HIS A  50
ASP A  49
TYR A  46
PRO A  37
 None
NA  A 150 (-2.5A)
None
None
 1.35A 3fo7A-1dpyA:
17.3		 3fo7A-1dpyA:
39.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
NA  A 150 (-2.5A)
None
None
 0.60A 3h1xA-1dpyA:
17.3		 3h1xA-1dpyA:
39.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		4 / 5 HIS A  50
ASP A  49
TYR A  46
PRO A  37
 None
NA  A 150 (-2.5A)
None
None
 1.30A 3h1xA-1dpyA:
17.3		 3h1xA-1dpyA:
39.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		6 / 9 LEU A   2
PHE A   5
ILE A   9
TRP A  19
GLY A  30
HIS A  48
 None
None
None
None
NA  A 150 (-4.5A)
None
 0.73A 3oshA-1dpyA:
20.2		 3oshA-1dpyA:
62.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 1dpy PHOSPHOLIPASE A2
(Bungarus
caeruleus) 		5 / 12 GLY A  30
GLY A  32
TYR A  52
ASN A  62
PRO A  63
 NA  A 150 (-4.5A)
NA  A 150 (-4.5A)
None
None
None
 1.03A 6ce2B-1dpyA:
16.8		 6ce2B-1dpyA:
36.07