SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dqs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 8 LEU A 320
MET A 295
GLU A 298
ALA A 299
 None
 0.78A 1a29A-1dqsA:
undetectable		 1a29A-1dqsA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		3 / 3 ALA A 302
VAL A 366
TRP A 269
 None
 0.91A 1bdwA-1dqsA:
undetectable
1bdwB-1dqsA:
undetectable		 1bdwA-1dqsA:
3.51
1bdwB-1dqsA:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 5 GLY A 191
LEU A 141
THR A 140
VAL A 195
 None
None
NAD  A 400 (-2.7A)
None
 1.10A 1ekjF-1dqsA:
undetectable
1ekjG-1dqsA:
2.1		 1ekjF-1dqsA:
21.09
1ekjG-1dqsA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 7 ASP A 119
GLU A 278
GLU A  81
GLU A 289
 NAD  A 400 (-3.1A)
NAD  A 400 ( 4.8A)
NAD  A 400 (-2.8A)
None
 1.15A 1knyA-1dqsA:
0.0
1knyB-1dqsA:
0.0		 1knyA-1dqsA:
20.05
1knyB-1dqsA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 12 HIS A 275
ALA A 279
GLY A 160
ASN A 268
GLU A 260
 CRB  A 401 (-4.2A)
None
None
CRB  A 401 (-3.0A)
None
 1.11A 1kxhA-1dqsA:
undetectable		 1kxhA-1dqsA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 7 GLU A 187
ARG A 333
LEU A 286
LEU A 325
GLY A 324
 NAD  A 400 (-3.4A)
None
None
None
None
 1.32A 1n13D-1dqsA:
0.0
1n13E-1dqsA:
undetectable		 1n13D-1dqsA:
16.53
1n13E-1dqsA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 8 LEU A 286
LEU A 325
GLY A 324
GLU A 187
ARG A 333
 None
None
None
NAD  A 400 (-3.4A)
None
 1.30A 1n13A-1dqsA:
undetectable
1n13F-1dqsA:
0.0		 1n13A-1dqsA:
11.59
1n13F-1dqsA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 6 GLU A 187
ARG A 333
LEU A 286
LEU A 325
GLY A 324
 NAD  A 400 (-3.4A)
None
None
None
None
 1.32A 1n13H-1dqsA:
0.0
1n13K-1dqsA:
undetectable		 1n13H-1dqsA:
16.53
1n13K-1dqsA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 7 LEU A 286
LEU A 325
GLY A 324
GLU A 187
ARG A 333
 None
None
None
NAD  A 400 (-3.4A)
None
 1.30A 1n13G-1dqsA:
undetectable
1n13J-1dqsA:
0.0		 1n13G-1dqsA:
11.59
1n13J-1dqsA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 8 ILE A 167
GLY A 151
GLY A 150
ILE A 149
ALA A 256
 None
 0.84A 1sguA-1dqsA:
undetectable		 1sguA-1dqsA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 10 GLU A  81
VAL A 116
GLY A 115
ASN A 162
HIS A 271
 NAD  A 400 (-2.8A)
NAD  A 400 (-3.9A)
NAD  A 400 (-3.3A)
NAD  A 400 (-3.7A)
ZN  A 402 ( 3.1A)
 1.28A 1v3qE-1dqsA:
2.1		 1v3qE-1dqsA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 12 TYR A 323
ILE A 196
PHE A 188
LEU A 180
MET A 144
 None
 1.14A 1xozA-1dqsA:
undetectable		 1xozA-1dqsA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		3 / 3 LYS A 341
ASP A 156
ASP A 119
 None
None
NAD  A 400 (-3.1A)
 1.11A 2br4A-1dqsA:
3.2		 2br4A-1dqsA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 10 LEU A 367
LEU A 301
ALA A 302
LEU A 391
VAL A 390
 None
 1.05A 2bxgB-1dqsA:
0.0		 2bxgB-1dqsA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 12 GLY A 114
GLY A 113
THR A 182
PHE A 179
ASP A  44
 NAD  A 400 (-3.0A)
None
NAD  A 400 (-3.7A)
None
NAD  A 400 (-2.6A)
 1.03A 2c49A-1dqsA:
3.1		 2c49A-1dqsA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 11 LEU A 263
ILE A 167
GLY A 150
ILE A 149
ALA A 256
 None
 0.93A 2idwA-1dqsA:
undetectable		 2idwA-1dqsA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 9 LEU A 286
HIS A 287
GLU A 278
HIS A 275
HIS A 271
 None
ZN  A 402 (-3.3A)
NAD  A 400 ( 4.8A)
CRB  A 401 (-4.2A)
ZN  A 402 ( 3.1A)
 1.47A 2jihA-1dqsA:
undetectable		 2jihA-1dqsA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_1
(PROTEASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 12 LEU A 263
ILE A 167
GLY A 151
GLY A 150
ILE A 149
 None
 0.92A 2o4kA-1dqsA:
0.0		 2o4kA-1dqsA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 4 HIS A 287
GLU A 278
HIS A 275
HIS A 271
 ZN  A 402 (-3.3A)
NAD  A 400 ( 4.8A)
CRB  A 401 (-4.2A)
ZN  A 402 ( 3.1A)
 1.32A 2ozrE-1dqsA:
undetectable		 2ozrE-1dqsA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 5 LEU A  10
GLY A 151
PRO A 170
ILE A 173
ILE A   9
 None
 1.35A 2q9rA-1dqsA:
0.5		 2q9rA-1dqsA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 7 SER A  14
ILE A  15
THR A 140
GLY A 118
 None
None
NAD  A 400 (-2.7A)
None
 0.97A 2v0mB-1dqsA:
0.0		 2v0mB-1dqsA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 12 GLY A 114
GLU A 278
VAL A 291
ASP A 146
ASP A 119
 NAD  A 400 (-3.0A)
NAD  A 400 ( 4.8A)
None
CRB  A 401 ( 2.9A)
NAD  A 400 (-3.1A)
 1.17A 2vqyA-1dqsA:
undetectable		 2vqyA-1dqsA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 5 HIS A 275
HIS A 271
VAL A 291
HIS A 287
 CRB  A 401 (-4.2A)
ZN  A 402 ( 3.1A)
None
ZN  A 402 (-3.3A)
 0.98A 2wkoF-1dqsA:
undetectable		 2wkoF-1dqsA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 9 LEU A 263
ILE A 167
GLY A 150
ILE A 149
ALA A 256
 None
 0.75A 3el0B-1dqsA:
undetectable		 3el0B-1dqsA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		6 / 12 GLY A 118
GLY A 150
GLY A 122
LEU A 267
VAL A 254
ILE A 149
 None
None
None
CRB  A 401 (-4.1A)
None
None
 1.47A 3elwA-1dqsA:
undetectable		 3elwA-1dqsA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		3 / 3 GLU A 278
VAL A 291
CYH A 290
 NAD  A 400 ( 4.8A)
None
None
 1.07A 3fbxA-1dqsA:
0.0		 3fbxA-1dqsA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		3 / 4 SER A 246
GLY A 288
GLU A  81
 None
None
NAD  A 400 (-2.8A)
 0.49A 3raeA-1dqsA:
0.0
3raeC-1dqsA:
3.7		 3raeA-1dqsA:
25.83
3raeC-1dqsA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_H_LFXH101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 5 SER A 246
GLY A 288
GLU A  81
GLU A 278
 None
None
NAD  A 400 (-2.8A)
NAD  A 400 ( 4.8A)
 1.26A 3raeB-1dqsA:
0.0
3raeD-1dqsA:
2.2		 3raeB-1dqsA:
25.83
3raeD-1dqsA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 9 ARG A 186
ALA A 193
GLY A 294
ILE A 293
LEU A 286
 None
 1.04A 3u7sB-1dqsA:
undetectable		 3u7sB-1dqsA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 8 ASP A 119
ASP A 355
ASN A 162
GLU A 278
 NAD  A 400 (-3.1A)
None
NAD  A 400 (-3.7A)
NAD  A 400 ( 4.8A)
 1.04A 4gkiE-1dqsA:
0.0
4gkiG-1dqsA:
0.0		 4gkiE-1dqsA:
19.70
4gkiG-1dqsA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		3 / 4 SER A 246
GLY A 288
GLU A  81
 None
None
NAD  A 400 (-2.8A)
 0.47A 4juoA-1dqsA:
0.0
4juoC-1dqsA:
3.5		 4juoA-1dqsA:
25.83
4juoC-1dqsA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 5 LEU A 325
PRO A 326
LEU A 320
ILE A 196
 None
 0.93A 4klrA-1dqsA:
3.9		 4klrA-1dqsA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 10 LEU A  21
PRO A 138
MET A 144
ALA A 247
LEU A 180
 None
 1.20A 4la0A-1dqsA:
1.1		 4la0A-1dqsA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 5 GLY A 372
SER A 202
PHE A 207
GLU A 206
 None
 0.99A 4m93B-1dqsA:
undetectable
4m93C-1dqsA:
undetectable		 4m93B-1dqsA:
18.54
4m93C-1dqsA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 12 LEU A 142
ASP A 146
GLU A 194
ASN A 162
HIS A 275
 NAD  A 400 (-3.7A)
CRB  A 401 ( 2.9A)
ZN  A 402 (-2.4A)
NAD  A 400 (-3.7A)
CRB  A 401 (-4.2A)
 1.36A 4pgfA-1dqsA:
3.7		 4pgfA-1dqsA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 6 LYS A 357
GLY A 262
GLY A 261
ASP A 257
 None
 1.03A 5a06D-1dqsA:
4.3		 5a06D-1dqsA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 7 ILE A 293
GLY A 294
LEU A 141
PHE A 188
 None
 0.82A 5hieB-1dqsA:
undetectable		 5hieB-1dqsA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 7 ASP A 355
GLY A 270
GLY A 274
HIS A 275
 None
None
None
CRB  A 401 (-4.2A)
 1.00A 5n9xA-1dqsA:
undetectable		 5n9xA-1dqsA:
24.60