SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dr9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 1dr9 T LYMPHOCYTE
ACTIVATION ANTIGEN
(Homo
sapiens) 		3 / 3 ASP A  76
LEU A  70
LEU A  72
 None
 0.59A 1ikeA-1dr9A:
0.3		 1ikeA-1dr9A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 1dr9 T LYMPHOCYTE
ACTIVATION ANTIGEN
(Homo
sapiens) 		3 / 3 ASP A  76
LEU A  70
LEU A  72
 None
 0.63A 1np1B-1dr9A:
undetectable		 1np1B-1dr9A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1dr9 T LYMPHOCYTE
ACTIVATION ANTIGEN
(Homo
sapiens) 		3 / 3 ASP A 107
THR A  13
GLU A  10
 None
 0.83A 2zifB-1dr9A:
undetectable		 2zifB-1dr9A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 1dr9 T LYMPHOCYTE
ACTIVATION ANTIGEN
(Homo
sapiens) 		4 / 5 ILE A 184
PRO A 137
PHE A 134
PRO A 135
 None
 1.23A 3bjwC-1dr9A:
0.0		 3bjwC-1dr9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1dr9 T LYMPHOCYTE
ACTIVATION ANTIGEN
(Homo
sapiens) 		4 / 5 TYR A  80
LEU A  14
LEU A  72
ARG A  56
 None
 1.50A 4em2A-1dr9A:
undetectable		 4em2A-1dr9A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1dr9 T LYMPHOCYTE
ACTIVATION ANTIGEN
(Homo
sapiens) 		4 / 6 VAL A 100
LEU A  65
SER A  66
ILE A  61
 None
 0.95A 5jw1A-1dr9A:
0.0		 5jw1A-1dr9A:
15.87