SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ds6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ds6 RHO GDP-DISSOCIATION
INHIBITOR 2
(Homo
sapiens) 		5 / 12 PHE B 141
VAL B  69
PHE B 178
VAL B 143
HIS B 112
 None
 1.29A 3u9fJ-1ds6B:
0.0
3u9fK-1ds6B:
0.0		 3u9fJ-1ds6B:
19.09
3u9fK-1ds6B:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1ds6 RHO GDP-DISSOCIATION
INHIBITOR 2
(Homo
sapiens) 		5 / 12 VAL B 126
LEU B 123
VAL B  69
LEU B  87
PHE B 113
 None
 1.20A 3w68A-1ds6B:
undetectable		 3w68A-1ds6B:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 1ds6 RHO GDP-DISSOCIATION
INHIBITOR 2
(Homo
sapiens) 		5 / 12 TYR B 107
SER B 105
ILE B 195
LEU B 193
LEU B  74
 None
 1.20A 5zwrB-1ds6B:
undetectable		 5zwrB-1ds6B:
18.45