SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ds9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		5 / 10 ALA A 137
LEU A 120
LEU A  88
ALA A  92
ILE A 111
 None
 1.23A 1g5yC-1ds9A:
undetectable		 1g5yC-1ds9A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		5 / 11 MET A  69
SER A  65
ILE A  34
ALA A   4
ALA A  42
 None
 1.36A 1jb0B-1ds9A:
undetectable		 1jb0B-1ds9A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		4 / 8 ILE A 111
ILE A  82
ASN A 116
VAL A 115
 None
 0.66A 2nniA-1ds9A:
0.0		 2nniA-1ds9A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		4 / 8 LEU A  53
LEU A  55
ALA A  22
ALA A  10
 None
 0.84A 2vcvF-1ds9A:
undetectable		 2vcvF-1ds9A:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		5 / 11 MET A  69
SER A  65
ILE A  34
ALA A   4
ALA A  42
 None
 1.36A 3pcqB-1ds9A:
undetectable		 3pcqB-1ds9A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		5 / 9 VAL A 115
LEU A 145
LEU A 147
ASN A 103
ILE A 100
 None
 1.41A 4c66A-1ds9A:
undetectable		 4c66A-1ds9A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		5 / 9 MET A  69
SER A  65
ILE A  34
ALA A   4
ALA A  42
 None
 1.33A 4fe1B-1ds9A:
undetectable		 4fe1B-1ds9A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		5 / 10 MET A  69
SER A  65
ILE A  34
ALA A   4
ALA A  42
 None
 1.23A 4xk8B-1ds9A:
undetectable		 4xk8B-1ds9A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		4 / 7 GLU A  61
ILE A  63
LEU A  98
ILE A  82
 None
 0.91A 4xumA-1ds9A:
0.0		 4xumA-1ds9A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 149
LEU A  81
ILE A  37
GLY A  32
LEU A  77
 None
 1.15A 4ze2A-1ds9A:
0.0		 4ze2A-1ds9A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		5 / 10 MET A  69
SER A  65
ILE A  34
ALA A   4
ALA A  42
 None
 1.39A 5oy0b-1ds9A:
undetectable		 5oy0b-1ds9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		4 / 8 MET A  33
ILE A  34
VAL A  21
GLU A  15
 None
 1.08A 6fbvC-1ds9A:
0.0		 6fbvC-1ds9A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ds9 OUTER ARM DYNEIN
(Chlamydomonas
reinhardtii) 		5 / 9 MET A  69
SER A  65
ILE A  34
ALA A   4
ALA A  42
 None
 1.40A 6hqbB-1ds9A:
undetectable		 6hqbB-1ds9A:
17.68