SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dts'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 1dts DETHIOBIOTIN
SYNTHETASE
(Escherichia
coli) 		4 / 6 ASN A 175
HIS A 184
ALA A 174
GLY A 201
 None
 1.12A 1gfzA-1dtsA:
undetectable		 1gfzA-1dtsA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1dts DETHIOBIOTIN
SYNTHETASE
(Escherichia
coli) 		5 / 10 ILE A 219
ILE A 203
GLY A 146
VAL A   6
LEU A 199
 None
 1.23A 3elzC-1dtsA:
0.0		 3elzC-1dtsA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 1dts DETHIOBIOTIN
SYNTHETASE
(Escherichia
coli) 		5 / 12 VAL A  39
ALA A  40
PHE A 128
PHE A 130
SER A  81
 None
 1.34A 4mm4A-1dtsA:
undetectable		 4mm4A-1dtsA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1dts DETHIOBIOTIN
SYNTHETASE
(Escherichia
coli) 		5 / 9 VAL A 173
LEU A  22
ALA A  21
VAL A   6
ILE A 142
 None
 1.17A 5om2A-1dtsA:
0.0
5om2B-1dtsA:
undetectable		 5om2A-1dtsA:
14.22
5om2B-1dtsA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 1dts DETHIOBIOTIN
SYNTHETASE
(Escherichia
coli) 		5 / 11 GLY A  35
ASP A 110
ALA A 109
SER A  62
LEU A  64
 None
 0.85A 5x6yA-1dtsA:
3.0		 5x6yA-1dtsA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 1dts DETHIOBIOTIN
SYNTHETASE
(Escherichia
coli) 		5 / 10 GLY A  35
ASP A 110
ALA A 109
SER A  62
LEU A  64
 None
 0.88A 5x6yB-1dtsA:
3.3		 5x6yB-1dtsA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 1dts DETHIOBIOTIN
SYNTHETASE
(Escherichia
coli) 		5 / 11 GLY A  35
ASP A 110
ALA A 109
SER A  62
LEU A  64
 None
 1.08A 5x6yC-1dtsA:
2.6		 5x6yC-1dtsA:
13.61