SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1du5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1du5 ZEAMATIN
(Zea
mays) 		4 / 8 THR A  35
SER A  31
THR A   4
VAL A   2
 None
 0.86A 4ik7B-1du5A:
1.3		 4ik7B-1du5A:
24.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 1du5 ZEAMATIN
(Zea
mays) 		4 / 7 LEU A  82
GLU A  84
SER A  99
ILE A 101
 None
 0.24A 4tvtA-1du5A:
32.9		 4tvtA-1du5A:
54.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 1du5 ZEAMATIN
(Zea
mays) 		4 / 8 THR A  81
ALA A 180
ASP A 186
SER A 190
 None
 1.13A 5l5fY-1du5A:
undetectable
5l5fZ-1du5A:
0.0		 5l5fY-1du5A:
20.94
5l5fZ-1du5A:
23.32