SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZVM_A_DM2A303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1dun	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (Equine infectious anemia virus)	5 / 12	GLY A 69 GLY A 68 ILE A 66 GLN A 80 ILE A 36	None	1.22A	4zvmA-1dunA: undetectable 4zvmB-1dunA: undetectable	4zvmA-1dunA: 19.91 4zvmB-1dunA: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGY_A_ERYA403_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	1dun	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (Equine infectious anemia virus)	5 / 12	ILE A 82 GLY A 68 PHE A 99 ALA A 100 ILE A 86	None	1.19A	5igyA-1dunA: 0.0	5igyA-1dunA: 18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	1dun	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (Equine infectious anemia virus)	4 / 8	GLN A 101 ALA A 60 GLN A 62 SER A 58	None	1.17A	5km8A-1dunA: undetectable 5km8B-1dunA: undetectable	5km8A-1dunA: 24.38 5km8B-1dunA: 24.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4ZVM_A_DM2A303_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1dun","DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE","Equine infectious anemia virus",5,"GLY A  69;GLY A  68;ILE A  66;GLN A  80;ILE A  36","None","1.22A","4zvmA-1dunA:undetectable;4zvmB-1dunA:undetectable","4zvmA-1dunA:19.91;4zvmB-1dunA:19.91"],["5IGY_A_ERYA403_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","1dun","DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE","Equine infectious anemia virus",5,"ILE A  82;GLY A  68;PHE A  99;ALA A 100;ILE A  86","None","1.19A","5igyA-1dunA:0.0","5igyA-1dunA:18.73"],["5KM8_B_L8PB201_1","HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL;HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL","1dun","DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE","Equine infectious anemia virus",4,"GLN A 101;ALA A  60;GLN A  62;SER A  58","None","1.17A","5km8A-1dunA:undetectable;5km8B-1dunA:undetectable","5km8A-1dunA:24.38;5km8B-1dunA:24.38"]]