SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1dus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 PHE A  35
THR A  44
GLY A  63
GLY A  65
ASN A 129
PRO A 131
 None
 0.78A 1nv8A-1dusA:
18.7		 1nv8A-1dusA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 PHE A  35
THR A  44
GLY A  63
GLY A  65
ILE A  69
PRO A 131
 None
 0.72A 1nv8B-1dusA:
18.7		 1nv8B-1dusA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAO_A_SAMA245_0
(ERMC'
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 GLY A  63
GLY A  65
ILE A  85
ASP A 113
ASN A 129
PRO A 131
 None
 0.61A 1qaoA-1dusA:
12.5		 1qaoA-1dusA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 PHE A  35
GLY A  65
ILE A  69
ASN A 129
PRO A 131
 None
 0.46A 1sg9A-1dusA:
18.9		 1sg9A-1dusA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 PHE A  35
THR A  44
GLY A  63
GLY A  65
ILE A  69
PRO A 131
 None
 0.73A 1sg9B-1dusA:
18.7		 1sg9B-1dusA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		3 / 3 GLY A  63
ASP A  84
ASN A 129
 None
 0.18A 1vq1A-1dusA:
18.9		 1vq1A-1dusA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 PHE A  35
THR A  44
GLY A  63
GLY A  65
ILE A  69
PRO A 131
 None
 0.68A 1vq1B-1dusA:
18.9		 1vq1B-1dusA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE A  90
ASN A  86
ILE A  85
ASP A  84
 None
 0.90A 1yc2E-1dusA:
4.2		 1yc2E-1dusA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		4 / 7 ASP A  31
ASN A  86
ILE A  90
ASP A  84
 None
 1.01A 1yc5A-1dusA:
3.3		 1yc5A-1dusA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		7 / 12 PHE A  35
ASP A  61
LEU A  62
GLY A  63
GLY A  65
ILE A  85
ASN A 129
 None
 0.60A 2nxeA-1dusA:
18.4		 2nxeA-1dusA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 PHE A  35
ASP A  61
GLY A  63
GLY A  65
ILE A  85
 None
 0.54A 2nxeB-1dusA:
18.5		 2nxeB-1dusA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 PHE A  35
ASP A  61
LEU A  62
GLY A  63
GLY A  65
ASN A 129
 None
 0.42A 2nxeB-1dusA:
18.5		 2nxeB-1dusA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 PHE A  35
GLY A  63
GLY A  65
ILE A  85
ASN A 129
 None
 0.72A 2zbpA-1dusA:
18.5		 2zbpA-1dusA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 PHE A  35
LEU A  62
GLY A  63
GLY A  65
ASN A 129
 None
 0.47A 2zbpA-1dusA:
18.5		 2zbpA-1dusA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 PHE A  35
GLY A  63
GLY A  65
ASN A 129
PRO A 131
 None
 0.30A 2zulA-1dusA:
20.4		 2zulA-1dusA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 10 ASP A  84
ILE A  85
ALA A  89
ASP A 113
LEU A  62
 None
 1.20A 3ay0A-1dusA:
20.5		 3ay0A-1dusA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 10 ASP A  84
ILE A  85
ASN A  86
ALA A  89
ASP A 113
 None
 0.37A 3ay0A-1dusA:
20.5		 3ay0A-1dusA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 10 GLY A  65
ASP A  84
ILE A  85
ASN A  86
ASP A 113
 None
 0.41A 3ay0B-1dusA:
20.5		 3ay0B-1dusA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 ASP A  61
GLY A  63
VAL A  68
ASP A  84
ILE A  85
 None
 0.59A 3cjtC-1dusA:
19.2		 3cjtC-1dusA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 ASP A  61
LEU A  62
GLY A  63
VAL A  68
ASP A  84
 None
 0.28A 3cjtC-1dusA:
19.2		 3cjtC-1dusA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  63
GLY A  65
VAL A  68
ILE A  85
ASN A 129
 None
 0.59A 3cjtG-1dusA:
19.2		 3cjtG-1dusA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A  62
GLY A  63
GLY A  65
VAL A  68
ASN A 129
 None
 0.35A 3cjtG-1dusA:
19.2		 3cjtG-1dusA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 LEU A  62
GLY A  63
GLY A  65
VAL A  68
ILE A  85
ASN A 129
 None
 0.61A 3cjtO-1dusA:
19.2		 3cjtO-1dusA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 PHE A  35
GLY A  63
GLY A  65
ASP A 113
ASN A 129
PRO A 131
 None
 0.33A 3dmfA-1dusA:
20.4		 3dmfA-1dusA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 PHE A  35
GLY A  63
GLY A  65
ASN A 129
PRO A 131
 None
 0.39A 3dmhA-1dusA:
20.4		 3dmhA-1dusA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRY_A_SAMA300_0
(DIMETHYLADENOSINE
TRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 GLY A  63
GLY A  65
ILE A  85
ASP A 113
ASN A 129
PRO A 131
 None
 1.03A 3gryA-1dusA:
13.8		 3gryA-1dusA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		3 / 3 GLY A  65
ASP A  84
ASP A 113
 None
 0.25A 3ou7C-1dusA:
13.2		 3ou7C-1dusA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		9 / 12 THR A  44
GLY A  63
ILE A  69
ASP A  84
ASN A  86
ASP A 113
LEU A 114
ASN A 129
PRO A 131
 None
 0.74A 3q87B-1dusA:
17.6		 3q87B-1dusA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A  37
ILE A  46
LEU A  47
LYS A  45
 None
 1.13A 3sueC-1dusA:
undetectable		 3sueC-1dusA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 11 GLY A  65
ASP A  84
ASP A 113
ASN A 129
PRO A 131
 None
 0.74A 3v8vB-1dusA:
11.9		 3v8vB-1dusA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		8 / 11 PHE A  35
ASP A  61
GLY A  63
GLY A  65
ILE A  69
ASP A  84
ASN A 129
PRO A 131
 None
 0.57A 4dcmA-1dusA:
14.5		 4dcmA-1dusA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  63
GLY A  65
ILE A  69
ASN A 129
PRO A 131
 None
 0.73A 4gc9A-1dusA:
10.3		 4gc9A-1dusA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  63
GLY A  65
ASP A  84
ILE A  85
ASP A 113
 None
 0.32A 4iv8A-1dusA:
14.8		 4iv8A-1dusA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV8_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  63
GLY A  65
ASP A  84
ILE A  85
ASP A 113
 None
 0.31A 4iv8B-1dusA:
15.0		 4iv8B-1dusA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  65
ASP A  84
ILE A  85
ASN A  86
PRO A 131
 None
 0.70A 4rtsA-1dusA:
13.2		 4rtsA-1dusA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  63
GLY A  65
ILE A  69
ILE A  85
ASN A  86
 None
 0.39A 5fa8A-1dusA:
5.6		 5fa8A-1dusA:
27.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 11 GLY A  65
ILE A  85
ASN A  86
ASP A 113
PRO A 131
 None
 0.51A 5hjiA-1dusA:
18.9		 5hjiA-1dusA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		6 / 12 GLY A  63
GLY A  65
ASP A  84
ILE A  85
ASN A  86
ILE A  69
 None
 1.29A 5wy0A-1dusA:
11.5		 5wy0A-1dusA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  63
GLY A  65
ASN A  86
ALA A  89
ASP A 113
 None
 0.79A 6b3aA-1dusA:
10.2		 6b3aA-1dusA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1dus MJ0882
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  63
GLY A  65
ASN A  86
ALA A  89
ASP A 113
 None
 0.81A 6b3bA-1dusA:
9.9		 6b3bA-1dusA:
14.58